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ChemicalBook >> CAS DataBase List >>[1R-[1(2S*,5R*),2beta,5alpha]]-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid 5-methyl-2-(1-methylethyl)cyclohexyl ester

[1R-[1(2S*,5R*),2beta,5alpha]]-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid 5-methyl-2-(1-methylethyl)cyclohexyl ester

[1R-[1(2S*,5R*),2beta,5alpha]]-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid 5-methyl-2-(1-methylethyl)cyclohexyl ester Structure
[1R-[1(2S*,5R*),2beta,5alpha]]-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid 5-methyl-2-(1-methylethyl)cyclohexyl ester structure
CAS No.
147126-75-8
Chemical Name:
[1R-[1(2S*,5R*),2beta,5alpha]]-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid 5-methyl-2-(1-methylethyl)cyclohexyl ester
Synonyms
FCME;Emtricitabine Impurity 23;Emtricitabine Impurity 38;The intermediate of his bin;Emtricitabine Menthyl Ester;EMtricitabine InterMediate- FCME;(2S,5R)-5-Fluoro cytosine-1-yl-[1,3]-oxathiolane-2-;[1R-[1(2S*,5R*),2beta,5alpha]]-5-(4-AMino-5-fluoro-2-oxo-1(2H)-;(2S,5R)-5-Fluoro cytosine-1-yl-[1,3]-oxathiolane-2-carboxyli...;(1R,2S,5R)-Methyl-5(S)-Flurorcytocine-1-Yl-[1,3]-Oxatholane-2Rcarboxylate
CBNumber:
CB2855107
Molecular Formula:
C18H26FN3O4S
Molecular Weight:
399.48
MDL Number:
MFCD22374171
MOL File:
147126-75-8.mol
MSDS File:
SDS
Last updated:2023-07-17 17:40:23
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[1R-[1(2S*,5R*),2beta,5alpha]]-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid 5-methyl-2-(1-methylethyl)cyclohexyl ester Properties

Melting point 180 - 183°C (dec.)
Boiling point 508.5±60.0 °C(Predicted)
Density 1.47
storage temp. Hygroscopic, Refrigerator, under inert atmosphere
solubility Chloroform (Slightly), Methanol (Slightly)
pka 2.40±0.10(Predicted)
form Solid
color White to Off-White
Stability Hygroscopic

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS03,GHS07,GHS09
Signal word  Warning
Hazard statements  H272-H302-H315-H319-H410
Precautionary statements  P221-P264b-P270-P280-P301+P312-P302+P352-P305+P351+P338-P330-P332+P313-P337+P313-P362+P364-P370+P378r-P403-P501c

[1R-[1(2S*,5R*),2beta,5alpha]]-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid 5-methyl-2-(1-methylethyl)cyclohexyl ester price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
AK Scientific J51430 (2S,5R)-(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylate 147126-75-8 100mg $49 2021-12-16 Buy
Matrix Scientific 099215 (2S,5R)-(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl 5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylate 95+% 147126-75-8 250mg $439 2021-12-16 Buy
Matrix Scientific 099215 (2S,5R)-(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl 5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylate 95+% 147126-75-8 1g $975 2021-12-16 Buy
American Custom Chemicals Corporation HCH0314401 5-METHYL-2-(1-METHYLETHYL)CYCLOHEXYL-5-(4-AMINO-5-FLUORO-2-OXO-1(2H)-PYRIMIDINYL)-1,3-OXATHIOLANE-2-CARBOXYLATE 98.00% 147126-75-8 5KG $6545 2021-12-16 Buy
Chemenu CM167355 (2S,5R)-(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylate 95% 147126-75-8 25g $184 2021-12-16 Buy
Product number Packaging Price Buy
J51430 100mg $49 Buy
099215 250mg $439 Buy
099215 1g $975 Buy
HCH0314401 5KG $6545 Buy
CM167355 25g $184 Buy

[1R-[1(2S*,5R*),2beta,5alpha]]-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid 5-methyl-2-(1-methylethyl)cyclohexyl ester Chemical Properties,Uses,Production

Uses

Emtricitabine Menthyl Ester is an impurity of Emtricitabine (E525000). Emtricitabine is a reverse transcriptase inhibitor. It is an effective antiviral agent against HIV, HBV, and other viruses replicating in a similar manner. A nucleoside analog structurally related to Lamivudine (L172500).

[1R-[1(2S*,5R*),2beta,5alpha]]-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid 5-methyl-2-(1-methylethyl)cyclohexyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

[1R-[1(2S*,5R*),2beta,5alpha]]-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid 5-methyl-2-(1-methylethyl)cyclohexyl ester Suppliers

Global( 149)Suppliers
Supplier Tel Email Country ProdList Advantage
Hangzhou ICH Biofarm Co., Ltd 		+undefined8613073685410 sales@ichemie.com China 985 58
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886 info@dakenam.com China 15928 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29914 58
Standardpharm Co. Ltd. 		86-714-3992388 overseasales1@yongstandards.com United States 14336 58
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19553 58
Chongqing Chemdad Co., Ltd 		+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63711 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 47465 58
Hubei Ipure Biology Co., Ltd 		+8613367258412 ada@ipurechemical.com China 10326 58
Supplier Advantage
Hangzhou ICH Biofarm Co., Ltd 		58
Shanghai Daken Advanced Materials Co.,Ltd 		58
Henan Tianfu Chemical Co.,Ltd. 		55
career henan chemical co 		58
Standardpharm Co. Ltd. 		58
BOC Sciences 		58
Chongqing Chemdad Co., Ltd 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
Hubei Ipure Biology Co., Ltd 		58

View Lastest Price from [1R-[1(2S*,5R*),2beta,5alpha]]-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid 5-methyl-2-(1-methylethyl)cyclohexyl ester manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
[1R-[1(2S*,5R*),2beta,5alpha]]-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid 5-methyl-2-(1-methylethyl)cyclohexyl ester pictures 2023-11-01 [1R-[1(2S*,5R*),2beta,5alpha]]-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid 5-methyl-2-(1-methylethyl)cyclohexyl ester
147126-75-8
 US $0.00-0.00 / kg 1kg 99% 500kg Hangzhou ICH Biofarm Co., Ltd
Emtricitabine Menthyl Ester pictures 2022-09-21 Emtricitabine Menthyl Ester
147126-75-8
 US $0.00-0.00 / kg 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
[1R-[1(2S*,5R*),2beta,5alpha]]-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid 5-methyl-2-(1-methylethyl)cyclohexyl ester pictures 2019-07-06 [1R-[1(2S*,5R*),2beta,5alpha]]-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid 5-methyl-2-(1-methylethyl)cyclohexyl ester
147126-75-8
 US $1.00 / kg 1kg 95%-99% 100kg Career Henan Chemical Co

147126-75-8([1R-[1(2S*,5R*),2beta,5alpha]]-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid 5-methyl-2-(1-methylethyl)cyclohexyl ester)Related Search:

(-)-EMtricitabine S-Oxide (Mixture of DiastereoMers) Aids005680 5-epi EMtricitabine Emtricitabine (+)-NEOMENTHOL
Emtricitabine Impurity 22 2-epi-(-)-EMtricitabine Emtricitabine Impurity 25 (2R,5S)-5-(5-Fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester (2S)-2-[[[(1,1-Dimethylethyl)diphenylsilyl]oxy]methyl]-1,3-oxathiolan-5-ol 5-Acetate
Emtricitabine Impurity 18 Emtricitabine Impurity 5-fluoro-1-(2-(hydroxymethyl)-1,3-dioxolan-4-yl)cytosine Ursodeoxycholic acid 2,4(1H,3H)-Pyrimidinedione,5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-, (2S-cis)- (9CI)
Emtricitabine Emtricitabine Impurity 8 ISOPULEGOL, TECH.

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[1R-[1(2S*,5R*),2beta,5alpha]]-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid 5-methyl-2-(1-methylethyl)cyclohexyl ester 5-(4-amino-5-fluoro-2-oxo-1(2h)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid 5-methyl-2-(1-methylethyl)cyclohexyl ester (2S,5R)-5-Fluoro cytosine-1-yl-[1,3]-oxathiolane-2-carboxylic acid menthyl ester (FCME) (2S,5R)-5-Fluoro cytosine-1-yl-[1,3]-oxathiolane-2-carboxylic acid menthyl ester (1''R,2''S,5''R)-MENTHYL-(2R-5R)-(4-AMINO-2-OXO-2H-5-FLUORO-PYRIMIDIN-1-YL)-[1,3]OXATHIOLANE (1R,2S,5R)-MENTHYL-5(S)-FLUOROCYTOSINE-1-YL-[1,3]-OXATHIOLANE-2R-CARBOXYLATE EMtricitabine InterMediate- FCME [1R-[1(2S*,5R*),2beta,5alpha]]-5-(4-AMino-5-fluoro-2-oxo-1(2H)- (2S,5R)-(1R,2S,5R)-2-Isopropyl-5-Methylcyclohexyl 5-(4-aMino-5-fluoro-2-oxopyriMidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylate (2S,5R)5(4AMINO-5-FLUORO2-OXO2H-PYRIMIDIN1YL)(1,3)OXATHIOLANE2CARBOXYLIC ACID2S-ISOPROPYL-5R-METHYL-1R-CYCLOHEYL ESTER (2R,5S)-5-(4-AMino-5-fluoro-2-oxo-2H-pyriMidin-1-yl)-[1,3]oxathiolane-2-carboxylic Acid,(2S)-Isopropyl-(5R)-Methyl-(1R)-cyclohexyl Ester FCME (2S,5R)-(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl 5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1, The intermediate of his bin 2R,5S-5-(4-AMINO-5-FLUORO-2-OXO-2H-PYRIMIDIN-1YL)-[1,3]-OXATHIOLANE-2-CARBOXYLIC ACID, 2S-ISOPROPYL-5R-METHYL-1R-CYCLOHXYL ESTER (1R, 2S, 5R)-MENTHYL-(2R, 5S)-5-(4-AMINO-5-FLUORO-2-OXO-2H-PYRIMIDIN-1-YL)-[1, 3]-OXATHIOLANE-2-CARBOXYLATE (2S,5R)-5-Fluoro cytosine-1-yl-[1,3]-oxathiolane-2-carboxylic acid methyl ester (2S,5R)-(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl 5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl) (2S,5R)-5-Fluoro cytosine-1-yl-[1,3]-oxathiolane-2- (5-methyl-2-propan-2-ylcyclohexyl) 5-(4-amino-5-fluoro-2-oxopyrimidin-1-yl)-1,3-oxathiolane-2-carboxylate Emtricitabine Impurity 23 Emtricitabine Menthyl Ester 1,3-Oxathiolane-2-carboxylic acid, 5-(4-amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-, (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester, (2S,5R)- Emtricitabine Impurity 38 (2S,5R)-5-Fluoro cytosine-1-yl-[1,3]-oxathiolane-2-carboxyli... [1R-[1(2S*,5R*),2beta,5alpha]]-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid 5-methyl-2-(1-methylethyl)cyclohexyl ester 5-(4-amino-5-fluoro-2-oxo-1(2h)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid 5-methyl-2-(1-methylethyl)cyclohexyl ester 5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid 5-methyl-2-(1-methylethyl)cyclohexyl ester CAS NO.147126-75-8 (1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl (2S,5R)-5-(4-amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylate (1R,2S,5R)-Methyl-5(S)-Flurorcytocine-1-Yl-[1,3]-Oxatholane-2Rcarboxylate Emtricitabine SM 5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2 carboxylic acid 5-methyl-2-(1-methylethyl)cyclohexyl ester 147126-75-8 (intermediate of emtricitabine)