tigloidine
- CAS No.
- 495-83-0
- Chemical Name:
- tigloidine
- Synonyms
- Tigloidin;Tiglyssin;tigloidine;Tigloyltropine;Tigloyltropeine;Tiglylpseudotropine;3α-Tigloyloxytropane;Tigloyl pseudotropine;2-Methylcrotonic acid (1R,5S)-tropan-3β-yl ester;2-Butenoic acid, 2-methyl-, (3-exo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, (2E)-
- CBNumber:
- CB2898322
- Molecular Formula:
- C13H21NO2
- Molecular Weight:
- 223.314
- MDL Number:
- MFCD00867194
- MOL File:
- 495-83-0.mol
| Boiling point | 290.2±33.0 °C(Predicted) |
|---|---|
| Density | 1.06±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| form | Oil |
| pka | 10.03±0.40(Predicted) |
| FDA UNII | 75GK1SV4EI |
tigloidine Chemical Properties,Uses,Production
Description
A tropine alkaloid isolated from Duboisia rnyoporoides, this base is a colourless syrup which yields crystalline salts. The hydrobromide forms colourless, tabular crystals m.p. 234-5°C and is optically inactive; the aurichloride crystallizes as yellow plates, m.p. 213.5- 2140 C; the picrate as yellow rectangular plates, m.p. 239°C and the methiodide as square plates, m.p. 244-5°C. The alkaloid is unsaturated and the hydro bromide, on hydrogenation, furnishes dihydrotigloidine, giving a picrate, m.p. l34-5°C. When treated with bromine in CHC13 it forms dibromodihydrotigloidine, m.p. 187°C (dec.). The free base may be hydrolyzed by boiling with H20 when it furnishes pseudotropine and tiglic acid. The base is therefore the tiglyl ester of pseudotropine. By comparison, tiglyltropine gives a hydrobromide with m.p. 207°C and a picrate, m.p. 200°C.
References
Barger, Martin, Mitchel1.,J. Chern. Soc., 1820 (1937)
tigloidine Preparation Products And Raw materials
Raw materials
Preparation Products
tigloidine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Shaanxi Didu New Materials Co. Ltd | +86-89586680 +86-13289823923 | 1026@dideu.com | China | 9116 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7892 | 56 |
| Wuhan ChemFaces Biochemical Co., Ltd. | 18607101326 15172504745 | aileen@chemfaces.com | China | 7059 | 55 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
| Sichuan BioCrick Biotech Co., Ltd | 28-85433893 | info@biocrick.com | CHINA | 4988 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223 | psaitong@jm-bio.com | China | 29834 | 58 |
| Beijing PUXI Standard Technology Co., Ltd. | 400-808-7372 13161114455; | info@rmuu.com | China | 4987 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24131 | 58 |