ChemicalBook >> CAS DataBase List >>Nestoron
Nestoron
- CAS No.
- 7759-35-5
- Chemical Name:
- Nestoron
- Synonyms
- ST 1435;NESTORON;NESTORONE;Elcometrine;Nestorone Acetate;Nestoron (ST-1435);Norgestone acetate;Segesterone Acetate;ELCOMETRINE;NESTORONE;ST-1435;ST1435;ELCOMETRINE; NESTORONE; ST-1435; ST 1435; ST1435
- CBNumber:
- CB31011778
- Molecular Formula:
- C23H30O4
- Molecular Weight:
- 370.48
- MDL Number:
- MFCD01711303
- MOL File:
- 7759-35-5.mol
Last updated:2024-01-04 15:13:51
| Melting point | 178-179° |
|---|---|
| alpha | D21 -105° (c = 1.2 in chloroform) |
| Boiling point | 420.37°C (rough estimate) |
| Density | 1.0550 (rough estimate) |
| refractive index | 1.4433 (estimate) |
| storage temp. | 2-8°C |
| solubility | DMSO: soluble5mg/mL, clear |
| form | powder |
| color | white to beige |
| InChIKey | CKFBRGLGTWAVLG-GOMYTPFNSA-N |
| EWG's Food Scores | 1 |
| FDA UNII | 9AMX4Q13CC |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|---|---|
| Signal word | Warning |
| Hazard statements | H351-H361 |
| Precautionary statements | P201-P202-P281-P308+P313-P405-P501-P201-P202-P281-P308+P313-P405-P501 |
| WGK Germany | 3 |
Nestoron price More Price(18)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML0550 | Nestorone ≥97% (HPLC) | 7759-35-5 | 10mg | $96.1 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML0550 | Nestorone ≥97% (HPLC) | 7759-35-5 | 50mg | $372 | 2024-03-01 | Buy |
| Cayman Chemical | 26441 | Segesterone Acetate | 7759-35-5 | 10mg | $78 | 2024-03-01 | Buy |
| Cayman Chemical | 26441 | Segesterone Acetate | 7759-35-5 | 25mg | $183 | 2024-03-01 | Buy |
| Cayman Chemical | 26441 | Segesterone Acetate | 7759-35-5 | 5mg | $44 | 2024-03-01 | Buy |
Nestoron Chemical Properties,Uses,Production
Uses
Segesterone Acetate has been used to study the: comparison of androgenic and estrogenic properties of progestins used in contraception and hormone therapy; impact on hepatic estrogen-sensitive proteins by 1-yr contraceptive vaginal ring delivering Nestorone and ethinyl estradiol.
Definition
ChEBI: Elcometrine is a corticosteroid hormone.
Pharmacokinetics
Elcometrine is a member of the 19-norprogesterone class of pr ogestins. when administered subcuta neously (implant), intravaginally (vaginal ring), or transdermally, elcometrine is an exceptionally potent progestin. It is 100-fold more potent when administered subcutaneously than when delivered orally. Its oral bioavaiability is only 10%，with a half life of just 1 to 2 hours because of rapid metabolism. The C16 methylene functionality substantially increases its affinity for the progesterone receptor.
Clinical Use
Because of its antiestrogenic action, elcometrine also can be administered transdermally along with estradiol as a treatment for menopausal symptoms .
Nestoron Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 78)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Yingrui Biopharma Co., Ltd. | +86-21-33585366 - 03@ | sales03@shyrchem.com | CHINA | 738 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 47465 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
| Alfa Chemistry | +1-5166625404 | Info@alfa-chemistry.com | United States | 21317 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
Related articles
- What is Segesterone acetate (Nestoron)?
- Segesterone acetate (SA; Nestoron) is a potent non-androgenic progestin that was developed for contraception and it is the pro....
- Jan 4，2024
7759-35-5(Nestoron)Related Search:
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1of4
ST 1435
NESTORONE
NESTORON
17-Hydroxy-16-methylene-19-norpregn-4-ene-3,20-dione acetate
Elcometrine
17-(ACETYLOXY)-16-METHYLENE-19-NORPREGN-4-ENE-20-DIONE
16-Methylene-17-hydroxy-19-norpregn-4-ene-3,20-dione acetate
16-Methylene-17-alpha-acetoxy-19-nor-4-pregnene-3,20-dione
19-Norpregn-4-ene-3,20-dione, 17-(acetyloxy)-16-methylene- (9ci)
19-Norpregn-4-ene-3,20-dione, 17-hydroxy-16-methylene-, acetate
Nestoron (ST-1435)
17-(Acetyloxy)-16-methylene-19-norpregn-4-ene-3,20-dione
ELCOMETRINE;NESTORONE;ST-1435;ST1435
Segesterone Acetate
(8R,9S,10R,13S,14S,17R)-17-acetyl-13-methyl-16-methylene-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate
ELCOMETRINE; NESTORONE; ST-1435; ST 1435; ST1435
19-Norpregn-4-ene-3,20-dione, 17-(acetyloxy)-16-methylene-
Estr-4-en-3-one,17-acetyl-17-(acetyloxy)-16-methylene-,(17α)-
Norgestone acetate
ST 1435,Inhibitor,Nestoron,ST1435,inhibit,Progesterone Receptor,NR3C3
Nestorone Acetate
7759-35-5
API