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Cetilistat

Cetilistat
Cetilistat structure
CAS No.
282526-98-1
Chemical Name:
Cetilistat
Synonyms
Cetilstat;cetilistat;New alistat;Xinli orlistat;Cetilistat(Alt-962);Cetilistat (ATL-962);Cetilistat (282526-98-1);2-hexadecoxy-6-methyl-3,1-benzoxazin-4-one;2-(Hexadecyloxy)-6-methyl-4H-3,1-benzoxazin-4-one;2-(Hexadecycloxy)-6-methyl-4H-3,1-benzoxazin-4-one
CBNumber:
CB31012078
Molecular Formula:
C25H39NO3
Formula Weight:
401.58
MOL File:
282526-98-1.mol

Cetilistat Properties

Melting point:
72.0 to 76.0 °C
Boiling point:
509.7±43.0 °C(Predicted)
Density 
1.02
pka
2.96±0.20(Predicted)
InChIKey
MVCQKIKWYUURMU-UHFFFAOYSA-N
CAS DataBase Reference
282526-98-1(CAS DataBase Reference)
FDA UNII
LC5G1JUA39

Cetilistat price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical C2745 Cetilistat >98.0%(HPLC) 282526-98-1 1g $81 2020-06-24 Buy
TCI Chemical C2745 Cetilistat >98.0%(HPLC) 282526-98-1 5g $264 2020-06-24 Buy

Cetilistat Chemical Properties,Uses,Production

Description

Cetilistat (also known as ATL-962) was approved in September 2013 by the Japanese Ministry of Health, Labor and Welfare for the treatment of obesity, limited to patients with both type 2 diabetes mellitus (T2DM) and dyslipidemia, and with a body mass index (BMI)25 kg/m2 in spite of dietary treatment and/or exercise therapy. As with orlistat, cetilistat works via inhibition of pancreatic lipases in the gut to inhibit fat absorption and thereby reduce caloric uptake from diet. The medicinal chemistry program has not been described in the scientific literature, but the patent describing cetilistat also describes the synthesis of analogs with varied aryl substituents and lipophilic tails. The synthesis of cetilistat involves condensation of a hexadecylcarbonochloridate with 2-amino-5-methylbenzoic acid; other analogs were synthesized by varying the carbonochloridate and 2-aminobenzoic acid components. Cetilistat is a potent inhibitor of human and rat pancreatic lipase with IC50s of 15 and 136 nM, respectively, with little inhibition of trypsin or chymotrypsin.

Chemical Properties

Off-white Cryst

Originator

Alizyme PLC (United Kingdom)

Uses

A novel pancreatic lipase inhibitor for the treatment of obesity in both diabetic and non-diabetic patients.

brand name

Oblean

Cetilistat Preparation Products And Raw materials

Raw materials

Preparation Products


Cetilistat Suppliers

Global( 245)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Honestpharm Co., Ltd
+86-15318812076
sale@jnhonestpharm.com; honestpharm@163.com; CHINA 292 58
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21837 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22625 55
Nanjing Finetech Chemical Co., Ltd.
025-85710122 17714198479
025-85710122 sales@fine-chemtech.com CHINA 890 55
ATK CHEMICAL COMPANY LIMITED
+86 21 5161 9050/ 5187 7795
+86 21 5161 9052/ 5187 7796 ivan@atkchemical.com CHINA 24754 60
Hebei Chishuo Biotechnology Co., Ltd.
13292891350 +86 311 66567340
luna@speedgainpharma.com CHINA 1009 58
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3623 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 30043 58
Zhejiang ZETian Fine Chemicals Co. LTD
+86-18957127338
QQ:800182836 stella@zetchem.com CHINA 2886 58
TianYuan Pharmaceutical CO.,LTD
+86-755-23284190 13684996853
+86-755-23284190 sales@tianpharm.com CHINA 305 58

View Lastest Price from Cetilistat manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2019-08-15 Cetilistat
282526-98-1
US $0.00-0.00 / g 1g 99 200kg/m Beijing Yibai Biotechnology Co., Ltd
2020-07-22 2-Hexadecyloxy-6-methyl-4H-3,1-benzoxazin-4-one
282526-98-1
US $10.00 / KG 1KG 98% 500 Ton/Tons per Month Hebei Xibaijie Biotechnology Co., Ltd.
2020-01-03 Cetilistat
282526-98-1
US $1.00 / KG 1KG 99% 2000kgs Yunbio Tech Co.,Ltd.

282526-98-1(Cetilistat)Related Search:


  • 4H-3,1-Benzoxazin-4-one,2-(hexadecyloxy)-6-Methyl-
  • Xinli orlistat
  • Cetilistat (282526-98-1)
  • cetilistat
  • Cetilistat(Alt-962)
  • Cetilstat
  • 2-(Hexadecycloxy)-6-methyl-4H-3,1-benzoxazin-4-one
  • 2-hexadecoxy-6-methyl-3,1-benzoxazin-4-one
  • New alistat
  • Cetilistat (ATL-962)
  • 2-(Hexadecyloxy)-6-methyl-4H-3,1-benzoxazin-4-one
  • 282526-98-1
  • Other series
  • Cetilistat
  • Aromatics
  • Heterocycles
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • API
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