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4-METHYLPYRAZOLE HYDROCHLORIDE

4-METHYLPYRAZOLE HYDROCHLORIDE Structure
4-METHYLPYRAZOLE HYDROCHLORIDE structure
CAS No.
56010-88-9
Chemical Name:
4-METHYLPYRAZOLE HYDROCHLORIDE
Synonyms
FOMEPIZOLE HYDROCHLORIDE;4-METHYLPYRAZOLE HYDROCHLORIDE;Fomepizole/FomepizolechlorideHCl;4-Methyl-1H-pyrazole hydrochloride;4-Methylpyrazole hydrochloride alcohol dehydrogenase inhibitor
CBNumber:
CB3106840
Molecular Formula:
C4H7ClN2
Molecular Weight:
118.56
MDL Number:
MFCD00012707
MOL File:
56010-88-9.mol
Last updated:2025-10-28 16:00:23
Product description Number Pack Size Price
4-Methylpyrazole hydrochloride alcohol dehydrogenase inhibitor M1387 100mg $150
4-Methylpyrazole hydrochloride alcohol dehydrogenase inhibitor M1387 1g $884
4-Methylpyrazole hydrochloride alcohol dehydrogenase inhibitor M1387 500mg $518
4-METHYLPYRAZOLE HYDROCHLORIDE 95.00% CHM0115061 100MG $634.02
4-METHYLPYRAZOLE HYDROCHLORIDE 95.00% CHM0115061 500MG $838.02
Request For Quotation

4-METHYLPYRAZOLE HYDROCHLORIDE Properties

Melting point 157-159 °C
storage temp. 2-8°C
solubility methanol: 100mg/mL, clear, colorless to yellow
form powder
color Purple to purplish red
biological source synthetic (organic)
UNSPSC Code 12352202
NACRES NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3

4-METHYLPYRAZOLE HYDROCHLORIDE price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich M1387 4-Methylpyrazole hydrochloride alcohol dehydrogenase inhibitor 56010-88-9 100mg $150 2025-07-31 Buy
Sigma-Aldrich M1387 4-Methylpyrazole hydrochloride alcohol dehydrogenase inhibitor 56010-88-9 1g $884 2025-07-31 Buy
Sigma-Aldrich M1387 4-Methylpyrazole hydrochloride alcohol dehydrogenase inhibitor 56010-88-9 500mg $518 2025-07-31 Buy
American Custom Chemicals Corporation CHM0115061 4-METHYLPYRAZOLE HYDROCHLORIDE 95.00% 56010-88-9 100MG $634.02 2021-12-16 Buy
American Custom Chemicals Corporation CHM0115061 4-METHYLPYRAZOLE HYDROCHLORIDE 95.00% 56010-88-9 500MG $838.02 2021-12-16 Buy
Product number Packaging Price Buy
M1387 100mg $150 Buy
M1387 1g $884 Buy
M1387 500mg $518 Buy
CHM0115061 100MG $634.02 Buy
CHM0115061 500MG $838.02 Buy

4-METHYLPYRAZOLE HYDROCHLORIDE Chemical Properties,Uses,Production

Uses

4-Methylpyrazole hydrochloride has been used:

  • as a cytochrome P450 2E1 inhibitor
  • as cytochrome P450 2E1 and alcohol dehydrogenase inhibitor in 1C11 neural progenitor cells
  • to inhibit ethanol oxidation in VL-17A cells expressing alcohol dehydrogenase and HepG2 cells

Biochem/physiol Actions

4-Methylpyrazole (4MP) inhibits ethanol oxidation in liver microsomes. It also blocks the c-Jun N-terminal kinase (JNK) activation in in vitro liver injury models.

in vivo

Pretreatment with Fomepizole (4-Methylpyrazole; 25 mg/kg; IP) prolongs ethanol neurobehavioral toxicity in CD-1 mice[4]

Animal Model:Male CD-1 mice weighing 18-25 g[4]
Dosage:25 mg/kg
Administration:IP; single dose
Result:Decreased the dose of ethanol (1-5 g/kg; IP) at which 50% of the animals failed a particular outcome test (toxic dose 50; TD50).

IC 50

CYP2E1

4-METHYLPYRAZOLE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

4-METHYLPYRAZOLE HYDROCHLORIDE Suppliers

Global( 30)Suppliers
Supplier Tel Email Country ProdList Advantage
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
TargetMol Chemicals Inc. 		+17819995354 marketing@targetmol.com United States 19961 58
Tianjin heowns Biochemical Technology Co., Ltd. 400 638 7771 sales@heowns.com China 14435 57
Spectrum Chemical Manufacturing Corp. 021-021-021-67601398-809-809-809 15221380277 marketing_china@spectrumchemical.com China 9658 60
SynAsst Chemical. 021-60343070 China 12740 55
Guangzhou Isun Pharmaceutical Co., Ltd 020-39119399 18927568969 isunpharm@qq.com China 4720 55
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51395 80
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44918 58
ChengDu SinoStandards Bio-Tech Co.,Ltd. ， 028-83243028 19136088901 sinostandards@163.com China 4976 58
Bide Pharmatech Ltd. 400-1647117 13681763483 product02@bidepharm.com China 59936 58
Supplier Advantage
Alchem Pharmtech,Inc. 		58
TargetMol Chemicals Inc. 		58
Tianjin heowns Biochemical Technology Co., Ltd. 57
Spectrum Chemical Manufacturing Corp. 60
SynAsst Chemical. 55
Guangzhou Isun Pharmaceutical Co., Ltd 55
Sigma-Aldrich 80
Energy Chemical 58
ChengDu SinoStandards Bio-Tech Co.,Ltd. ， 58
Bide Pharmatech Ltd. 58

View Lastest Price from 4-METHYLPYRAZOLE HYDROCHLORIDE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Fomepizole hydrochloride pictures 2025-10-27 Fomepizole hydrochloride
56010-88-9
 US $1980.00-2500.00 / mg 10g TargetMol Chemicals Inc.

4-METHYLPYRAZOLE HYDROCHLORIDE Spectrum

4-METHYLPYRAZOLE HYDROCHLORIDE(56010-88-9)Raman

56010-88-9(4-METHYLPYRAZOLE HYDROCHLORIDE)Related Search:

5-AMINO-1-(4-CHLOROPHENYL)-1H-PYRAZOLE-4-CARBONITRILE 2-(4-CHLOROPHENYL)-3-(TRIFLUOROMETHYL)PYRAZOLE-4-CARBONYL CHLORIDE 5-CHLORO-3-METHYL-1-PHENYL-1H-PYRAZOLE-4-CARBALDEHYDE 5-CHLORO-1-METHYL-3-(TRIFLUOROMETHYL)PYRAZOLE-4-CARBOXALDEHYDE (-)-QUINPIROLE HYDROCHLORIDE
1-PHENYL-5-(TRIFLUOROMETHYL)PYRAZOLE-4-CARBONYL CHLORIDE Dichlorosulfophenyl-3-methylpyrazolone 5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde 1-(4-CHLOROPHENYL)-5-PROPYL-1H-PYRAZOLE-4-CARBOXYLIC ACID 4-Methylpyrazole
ETHYL 1-(4-CHLOROPHENYL)-5-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLATE 2-(4-CHLOROPHENYL)-3-(TRIFLUOROMETHYL)PYRAZOLE-4-CARBOXYLIC ACID 1-(3-CHLOROPHENYL)-5-(1H-PYRROL-1-YL)-1H-PYRAZOLE-4-CARBONITRILE 5-AMINO-1-(3-CHLORO-4-FLUOROPHENYL)-4-CYANOPYRAZOLE 2-(4-CHLOROPHENYL)-3-(TRIFLUOROMETHYL)PYRAZOLE-4-CARBOXYLIC ACID HYDRAZIDE
4-METHYLPYRAZOLE HYDROCHLORIDE 5-AMINO-1-(2,4-DICHLOROPHENYL)-1H-PYRAZOLE-4-CARBONITRILE 5-CHLORO-3-[2-(DIMETHYLAMINO)-1-FORMYLVINYL]-1-PHENYL-1H-PYRAZOLE-4-CARBOXALDEHYDE

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FOMEPIZOLE HYDROCHLORIDE 4-METHYLPYRAZOLE HYDROCHLORIDE Fomepizole/FomepizolechlorideHCl 4-Methyl-1H-pyrazole hydrochloride 4-Methylpyrazole hydrochloride alcohol dehydrogenase inhibitor 56010-88-9 A to C Biochemicals and Reagents BioChemical Alcohol dehydrogenase human Enzyme Inhibitors Enzymes, Inhibitors, and Substrates Enzyme Inhibitors by Enzyme