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JP1302
- CAS No.
- 80259-18-3
- Chemical Name:
- JP1302
- Synonyms
- JP1302;MMV006172;Brn 5117597;JP 1302 dihydrochloride;N-(4-(4-Methylpiperazin-1-yl)phenyl)acridin-9-amine;N-(4-(4-Methyl-1-piperazinyl)phenyl)-9-acridinamine;9-Acridinamine, N-(4-(4-methyl-1-piperazinyl)phenyl)-;JP1302(9-Acridinamine, N-[4-(4-methyl-1-piperazinyl)phenyl]-);N-[4-(4-Methyl-1-piperazinyl)phenyl]-9-acridinaminedihydrochloride
- CBNumber:
- CB31075143
- Molecular Formula:
- C24H24N4
- Molecular Weight:
- 368.47
- MDL Number:
- MFCD10565599
- MOL File:
- 80259-18-3.mol
Last updated:2023-07-02 08:28:07
| Boiling point | 550.9±50.0 °C(Predicted) |
|---|---|
| Density | 1.227±0.06 g/cm3(Predicted) |
| storage temp. | Desiccate at -20°C |
| pka | 9.03±0.10(Predicted) |
| Water Solubility | <44.14mg/ml in Water |
| EWG's Food Scores | 1 |
JP1302 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Tocris | 2666 | JP1302dihydrochloride ≥99%(HPLC) | 80259-18-3 | 10 | $233 | 2021-12-16 | Buy |
| Tocris | 2666 | JP1302dihydrochloride ≥99%(HPLC) | 80259-18-3 | 50 | $980 | 2021-12-16 | Buy |
| Usbiological | 255566 | JP 1302 dihydrochloride | 80259-18-3 | 10mg | $480 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0008021 | JP 1302 DIHYDROCHLORIDE 95.00% | 80259-18-3 | 10MG | $727.65 | 2021-12-16 | Buy |
| ApexBio Technology | B7147 | JP1302dihydrochloride | 80259-18-3 | 10mg | $338 | 2021-12-16 | Buy |
JP1302 Chemical Properties,Uses,Production
Uses
JP 1302 Dihydrochloride is an α2-adrenoceptor blocker and can be used for the treatment or prevention of nephropathy.
Biological Activity
α 2C -adrenoceptor antagonist that displays ~ 50-fold selectivity over other α 2 -adrenoceptor subtypes (K i values are 28, 1470, 1700 and 3150 nM for human α 2C , α 2B , α 2D and α 2A subtypes respectively). Potently antagonizes adrenalin-stimulated 35 GTP γ S binding in vitro (K B = 16 nM) and produces antidepressant and antipsychotic-like effects in vivo .
JP1302 Preparation Products And Raw materials
Raw materials
Preparation Products
JP1302 Suppliers
Global( 29)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| VDM Biochemicals | 0330-2528181 | sales@vdmbio.com | United States | 510 | 64 |
| Shanghaizehan biopharma technology co., Ltd. | 021-61350663 13052117465 | sales@zehanbiopharma.com | China | 996 | 55 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 3413 | 55 |
| Shanghai Chaolan Chemical Technology Center | QQ:65489617 15618227136 | info@SuperLan-chem.com | China | 9364 | 58 |
| Chengdu Saint - Kay Biotechnology Co., Ltd. | 028-85157043 15882256948 | 676046971@qq.com | China | 4391 | 58 |
| Hefei Mokai Pharmaceutical Technology Co., Ltd | 18130062233 | 3362556465@qq.com | China | 8000 | 58 |
80259-18-3(JP1302)Related Search:
JP1302
9-Acridinamine, N-(4-(4-methyl-1-piperazinyl)phenyl)-
Brn 5117597
N-(4-(4-Methyl-1-piperazinyl)phenyl)-9-acridinamine
JP 1302 dihydrochloride
N-[4-(4-Methyl-1-piperazinyl)phenyl]-9-acridinaminedihydrochloride
JP1302(9-Acridinamine, N-[4-(4-methyl-1-piperazinyl)phenyl]-)
MMV006172
N-(4-(4-Methylpiperazin-1-yl)phenyl)acridin-9-amine
80259-18-3
C24H24N42HCl
Potently antagonizes adrenalin-stimulated 35GTPγS binding in vitro (KB = 16 nM) and produces antidepressant and antipsychotic-like effects in vivo.