ChemicalBook >> CAS DataBase List >>(-)-6-8-DIFLUORO-2,3,4,9-TETRAHYDRO-9-[[4-(METHYLSULFONYL)PHENYL]METHYL]-1H-CARBAZOLE-1-ACETIC ACID

(-)-6-8-DIFLUORO-2,3,4,9-TETRAHYDRO-9-[[4-(METHYLSULFONYL)PHENYL]METHYL]-1H-CARBAZOLE-1-ACETIC ACID

(-)-6-8-DIFLUORO-2,3,4,9-TETRAHYDRO-9-[[4-(METHYLSULFONYL)PHENYL]METHYL]-1H-CARBAZOLE-1-ACETIC ACID structure

CAS No.: 121083-05-4

Chemical Name:: (-)-6-8-DIFLUORO-2,3,4,9-TETRAHYDRO-9-[[4-(METHYLSULFONYL)PHENYL]METHYL]-1H-CARBAZOLE-1-ACETIC ACID

Synonyms: L-670,596;L670,596,L 670,596;2-(6,8-Difluoro-9-(4-(methylsulfonyl)benzyl)-2,3,4,9-tetrahydro-1H-carbazol-1-yl)acetic acid;(-)-6-8-DIFLUORO-2,3,4,9-TETRAHYDRO-9-[[4-(METHYLSULFONYL)PHENYL]METHYL]-1H-CARBAZOLE-1-ACETIC ACID

CBNumber:: CB3118579

Molecular Formula:: C22H21F2NO4S

Molecular Weight:: 433.47

MDL Number:: MFCD00880316

MOL File:: 121083-05-4.mol

Last updated:2023-05-18 11:31:02

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(-)-6-8-DIFLUORO-2,3,4,9-TETRAHYDRO-9-[[4-(METHYLSULFONYL)PHENYL]METHYL]-1H-CARBAZOLE-1-ACETIC ACID Properties

Boiling point	693.4±55.0 °C(Predicted)
Density	1.43±0.1 g/cm3(Predicted)
storage temp.	Store at RT
solubility	Soluble to 100 mM in 1.1eq. NaOH
form	Powder
pka	4.56±0.10(Predicted)

(-)-6-8-DIFLUORO-2,3,4,9-TETRAHYDRO-9-[[4-(METHYLSULFONYL)PHENYL]METHYL]-1H-CARBAZOLE-1-ACETIC ACID price More Price(6)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Tocris	1949	L-670,596 ≥98%(HPLC)	121083-05-4	10	$144	2021-12-16	Buy
TRC	L676020	L-670,596	121083-05-4	2.5mg	$275	2021-12-16	Buy
Usbiological	453155	L-670,596	121083-05-4	1mg	$410	2021-12-16	Buy
Usbiological	255636	L-670,596	121083-05-4	10mg	$466	2021-12-16	Buy
American Custom Chemicals Corporation	HCH0135731	(-)-6-8-DIFLUORO-2,3,4,9-TETRAHYDRO-9-[[4-(METHYLSULFONYL)PHENYL]METHYL]-1H-CARBAZOLE-1-ACETIC ACID 95.00%	121083-05-4	1G	$1004.85	2021-12-16	Buy

Product number	Packaging	Price	Buy
1949	10	$144	Buy
L676020	2.5mg	$275	Buy
453155	1mg	$410	Buy
255636	10mg	$466	Buy
HCH0135731	1G	$1004.85	Buy

(-)-6-8-DIFLUORO-2,3,4,9-TETRAHYDRO-9-[[4-(METHYLSULFONYL)PHENYL]METHYL]-1H-CARBAZOLE-1-ACETIC ACID Chemical Properties,Uses,Production

Uses

L-670,596 is a potent and selective thromboxane/prostaglandin endoperoxide receptor antagonist.

Definition

ChEBI: 2-[6,8-difluoro-9-[(4-methylsulfonylphenyl)methyl]-1,2,3,4-tetrahydrocarbazol-1-yl]acetic acid is a member of carbazoles.

Biological Activity

Potent and selective thromboxane A 2 /prostaglandin endoperoxide receptor antagonist (IC 50 = 5.5 nM). Inhibits U-44069-induced contractions of guinea pig trachea (pA 2 = 9.0) and human platelet aggregation in vitro (IC 50 = 6.5 nM). Also prevents thromboxane-mediated endothelial cell death. Orally active in vivo .

(-)-6-8-DIFLUORO-2,3,4,9-TETRAHYDRO-9-[[4-(METHYLSULFONYL)PHENYL]METHYL]-1H-CARBAZOLE-1-ACETIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

(-)-6-8-DIFLUORO-2,3,4,9-TETRAHYDRO-9-[[4-(METHYLSULFONYL)PHENYL]METHYL]-1H-CARBAZOLE-1-ACETIC ACID Suppliers

Global( 19)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63711	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Aceschem Inc.	+1-817863-6948 +1-（817）863-6948	sales@aceschem.com	United States	19639	58
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8449	60
BOC Sciences	--	info@bocsci.com	USA	0	65
Changzhou Bojia Biomedical Technology Co., Ltd.	2122619822	czbjpharma@126.com	China	18488	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24131	58
Nantong QuanYi Biotechnology Co., Ltd	0513-66337626 18051384581	sales@chemhifuture.com	China	4028	58
ApexBio Technology	--	sales@apexbt.com	United States	6254	58

Supplier	Advantage
Alchem Pharmtech,Inc.	58
TargetMol Chemicals Inc.	58
Aceschem Inc.	58
3B Pharmachem (Wuhan) International Co.,Ltd.	69
EMMX Biotechnology LLC	60
BOC Sciences	65
Changzhou Bojia Biomedical Technology Co., Ltd.	58
TargetMol Chemicals Inc.	58
Nantong QuanYi Biotechnology Co., Ltd	58
ApexBio Technology	58

121083-05-4((-)-6-8-DIFLUORO-2,3,4,9-TETRAHYDRO-9-[[4-(METHYLSULFONYL)PHENYL]METHYL]-1H-CARBAZOLE-1-ACETIC ACID)Related Search:

N-BENZYL-1,2,3,4-TETRAHYDROCARBAZOLE 7-Fluoroindole 5,7-Difluoroindole 4-METHYLSULFONYLBENZYLAMINE HYDROCHLORIDE 5-Fluoro-2-methylindole

6-(1H-INDOL-3-YL)HEXANOIC ACID 3-(1H-Pyrrol-2-yl)propanoic acid 5-Fluoro-2,3-dimethyl-1H-indole (-)-6-8-DIFLUORO-2,3,4,9-TETRAHYDRO-9-[[4-(METHYLSULFONYL)PHENYL]METHYL]-1H-CARBAZOLE-1-ACETIC ACID

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L-670,596 (-)-6-8-DIFLUORO-2,3,4,9-TETRAHYDRO-9-[[4-(METHYLSULFONYL)PHENYL]METHYL]-1H-CARBAZOLE-1-ACETIC ACID 2-(6,8-Difluoro-9-(4-(methylsulfonyl)benzyl)-2,3,4,9-tetrahydro-1H-carbazol-1-yl)acetic acid L670,596,L 670,596 121083-05-4 C22H21F2NO4S Prostanoid receptor and related