DOTAP
- CAS No.
- 144189-73-1
- Chemical Name:
- DOTAP
- Synonyms
- DOTAP;DOTAP MS;DOTAP METHOSULFATE;DOTAP methyl sulfate;TRANSFECTION REAGENT;18:1 TAP (DOTAP, MS Salt);DOTAP Transfection Reagent;TRANSFAST(TM) TRANSFECTION REAGENT;TFX(TM) REAGENTS TRANSFECTION TRIO;DOTAP Liposomal Transfection Reagent
- CBNumber:
- CB3122792
- Molecular Formula:
- C42H80NO4.CH3O4S
- Molecular Weight:
- 774.19
- MDL Number:
- MFCD16660441
- MOL File:
- 144189-73-1.mol
- MSDS File:
- SDS
| Density | 1.11 g/cm3 |
|---|---|
| storage temp. | 2-8°C |
| form | buffered aqueous suspension |
| color | clear to hazy colorless to faint yellow |
| FDA UNII | MR86K0XRQP |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS06,GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H302-H315-H319-H331-H336-H351-H361d-H372 |
| Precautionary statements | P202-P301+P312-P302+P352-P304+P340+P311-P305+P351+P338-P308+P313 |
| WGK Germany | 3 |
DOTAP price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 11202375001 | DOTAP Liposomal Transfection Reagent N-[1-(2,3-Dioleoyloxy)propyl]-N,N,N-trimethylammonium methyl-sulfate | 144189-73-1 | 5x400μL | $598 | 2024-03-01 | Buy |
| Usbiological | T8198-02 | Transfection Reagent | 144189-73-1 | 120ul | $1042 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD157467 | N-[1-(2,3-Dioleoyloxy)propyl]-n,n,n-trimethylammonium methyl-sulfate | 144189-73-1 | 250mg | $325 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD157467 | N-[1-(2,3-Dioleoyloxy)propyl]-n,n,n-trimethylammonium methyl-sulfate | 144189-73-1 | 500mg | $500 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CBL0000340 | DOTAP METHOSULFATE 95.00% | 144189-73-1 | 1G | $605.15 | 2021-12-16 | Buy |
DOTAP Chemical Properties,Uses,Production
Description
18:1 TAP (DOTAP, MS Salt) is a cationic derivative of trimethylammonium linked with two 18-carbon fatty acid tails with single alkene groups in each tail. 18:1 TAP is a cationic liposome-forming compound that may be used for transfection of DNA, RNA, and other negatively charged molecules into eukaryotic cells.
Uses
The DOTAP (N-[1-(2,3-Dioleoyloxy)propyl]-N,N,N-trimethylammonium methyl-sulfate) Liposomal Transfection Reagent is a liposome formulation of the cationic lipid DOTAP. DOTAP can be used for the highly efficient transfection of DNA including yeast artificial chromosomes (YACs) into eukaryotic cells for transient or stable gene expression, and is also suitable for the efficient transfer of other negatively charged molecules, such as RNA, oligonucleotides, nucleotides, ribonucleo-protein (RNP) complexes, and proteins into research samples of mammalian cells.
General Description
DOTAP Liposomal Transfection Reagent is a liposome formulation of the cationic lipid DOTAP. Unlike other liposomal reagents, it produces highly efficient transfections both in the presence and absence of serum. It can also be successfully used for in vivo applications. Mixing DOTAP with DNA results in spontaneously formed stable complexes. These complexes can be added directly to the cell culture medium. This method of DNA transfer is very gentle, avoiding the cytotoxic effects commonly encountered with lipofection or other transfection methods.
Biochem/physiol Actions
DOTAP (1,2-dioleoyl-3-trimethylammonium-propane) is a cationic lipid, used for in vitro and in vivo nucleic acid and protein delivery. The lipid composition and cell type affects the transfection potential of DOTAP. DOTAP mediates gene knockdown technique in hematopoietic stem cells (HSCs).
DOTAP Preparation Products And Raw materials
Raw materials
Preparation Products
DOTAP Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shochem(Shanghai) Co.,Ltd | 86-21-50800795 | info@shochem.com | CHINA | 288 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 12468 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| XIAMEN SINOPEG BIOTECH CO., LTD. | +86-0592-7761068 +8617350879715 | changaiwei@sinopeg.com | China | 59 | 58 |
| Baoji Guokang Bio-Technology Co., Ltd. | 0917-3909592 13892490616 | gksales1@gk-bio.com | China | 9339 | 58 |
| BOC Sciences | +16314854226 | inquiry@bocsci.com | United States | 19743 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42057 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Guangzhou Weihua Biotechnology Co., Ltd | 020-020-37239396 18922492046 | weihuasw@foxmail.com | China | 2052 | 58 |
View Lastest Price from DOTAP manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-07-13 | DOTAP
144189-73-1
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
 |
2021-07-09 | DOTAP
144189-73-1
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
 |
2021-07-07 | 1,2-dioleoyl-3-trimethylammonium propane (methyl sulfate salt)
144189-73-1
|
US $0.00-0.00 / g | 1g | 98% | 1 | XIAMEN SINOPEG BIOTECH CO., LTD. |
-
- DOTAP
144189-73-1
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- DOTAP
144189-73-1
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 1,2-dioleoyl-3-trimethylammonium propane (methyl sulfate salt)
144189-73-1
- US $0.00-0.00 / g
- 98%
- XIAMEN SINOPEG BIOTECH CO., LTD.