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1,2-O-Isopropylidene-a-L-xylofuranose

1,2-O-Isopropylidene-a-L-xylofuranose structure

CAS No.: 114861-22-2

Chemical Name:: 1,2-O-Isopropylidene-a-L-xylofuranose

Synonyms: SOTA-002;1,2-O-Isopropylidene-α-L-xylofuranose;1,2-O-Isopropylidene-L-D-xylofuranose;1,2-O-isopropylidene-α-L-xylofuranose;1,2-O-Isopropylidene-a-L-xylofuranose;1,2-O-Isopropylidene-alpha-L-xylofuranose;a-L-Xylofuranose,1,2-O-(1-methylethylidene)-;α-L-Xylofuranose, 1,2-O-(1-Methylethylidene)-;2,3,5-Tri-O-benzoyl-α-D-arabinofuranosyl Bromide;(3AS,5S,6R,6AS)-5-(HYDROXYMETHYL)-2,2-DIMETHYL-3A,5,6,6A-TETRAHYDROFURO[2,3-D][1,3]DIOXOL-6-OL

CBNumber:: CB31231282

Molecular Formula:: C8H14O5

Molecular Weight:: 190.19

MDL Number:: MFCD00010529

MOL File:: 114861-22-2.mol

MSDS File:: SDS

Last updated:2025-09-25 17:15:13

Product description	Number	Pack Size	Price
1,2-O-Isopropylidene-a-L-xylofuranose	293718	1g	$375
1-2-O-Isopropylidene-α-L-xylofuranose	O106876	1g	$390
1,2-O-Isopropylidene-a-L-xylofuranose	MI01012	10g	$472.5
1-2-O-Isopropylidene-α-L-xylofuranose	O106876	5G	$663
(3As,5S,6R,6aS)-5-(Hydroxymethyl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-6-ol	5596CR	10g	$687
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1,2-O-Isopropylidene-a-L-xylofuranose Properties

Boiling point	333.0±37.0 °C(Predicted)
Density	1.267±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
pka	13.23±0.60(Predicted)
InChI	InChI=1/C8H14O5/c1-8(2)12-6-5(10)4(3-9)11-7(6)13-8/h4-7,9-10H,3H2,1-2H3/t4-,5+,6-,7-/s3
InChIKey	JAUQZVBVVJJRKM-TWULDSOMNA-N
SMILES	[C@H]12OC(C)(C)O[C@H]1[C@@H]([C@H](CO)O2)O \|&1:0,6,7,8,r\|

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P301+P312-P302+P352-P304+P340-P305+P351+P338

1,2-O-Isopropylidene-a-L-xylofuranose price More Price(15)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Usbiological	293718	1,2-O-Isopropylidene-a-L-xylofuranose	114861-22-2	1g	$375	2021-12-16	Buy
Medical Isotopes, Inc.	O106876	1-2-O-Isopropylidene-α-L-xylofuranose	114861-22-2	1g	$390	2021-12-16	Buy
Biosynth Carbosynth	MI01012	1,2-O-Isopropylidene-a-L-xylofuranose	114861-22-2	10g	$472.5	2021-12-16	Buy
Medical Isotopes, Inc.	O106876	1-2-O-Isopropylidene-α-L-xylofuranose	114861-22-2	5G	$663	2021-12-16	Buy
AK Scientific	5596CR	(3As,5S,6R,6aS)-5-(Hydroxymethyl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-6-ol	114861-22-2	10g	$687	2021-12-16	Buy

Product number	Packaging	Price	Buy
293718	1g	$375	Buy
O106876	1g	$390	Buy
MI01012	10g	$472.5	Buy
O106876	5G	$663	Buy
5596CR	10g	$687	Buy

1,2-O-Isopropylidene-a-L-xylofuranose Chemical Properties,Uses,Production

Uses

1,2-O-Isopropylidene-a-L-xylofuranose can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly in laboratory research and development processes and chemical production processes.

Synthesis

((3aS,5R,6S,6aS)-6-Hydroxy-2,2-dimethyltetrahydrofuro[3,2-d][1,3]dioxol-5-yl)(morpholino)methanone (134). Step 1) (3aS,5S,6R,6aS)-5-(Hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,2-d][1,3]dioxol-6-ol. To a suspension of L-(-)-xylose (133, 19.15 g, 127.5 mmol) and MgSO4 (30.72 g, 255.0 mmol) in acetone (190 mL) was added conc. H2SO4 (1.9 mL) at room temperature. After 12 h, the reaction mixture (all L-(-)-xylose had been consumed) was filtered and the collected solids were washed with acetone (twice, 20 mL per wash). The stirring yellow filtrate was neutralized with NH4OH solution to pH ~ 9. The suspended solids were removed by filtration. The filtrate was concentrated to afford crude bis-acetonide intermediate as yellow oil. The yellow oil was suspended in water (5 mL), and then the pH was adjusted from 9 to 2 with 1 N HCl in water solution. The reaction mixture was stirred for 12 h at room temperature. The resulting mixture was neutralized by the addition of 25% (w/w) K3PO4 in water until pH ~ 7. The mixture was extracted with EtOAc. The organic layer was dried over MgSO4 filtered, and concentrated in vacuo. The crude product was purified by silica gel column chromatography. Yield: (12.63 g, 52%) as yellow oil. 1H NMR (400 MHz, CD3OD) δ 5.88 (d, J = 4.0 Hz, 1H), 4.47 (d, J 4.0 Hz, 1H), 4.18-4.14 (m, 1H), 4.1 1 (d, J = 2.8 Hz, 1H), 3.83-3.71 (m, 2H), 1.45 (s, 3H), 1.29 (s, 3H).

References

[1] RSC Advances, 2016, vol. 6, # 46, p. 39758 - 39761
[2] Tetrahedron, 1981, vol. 37, p. 1685 - 1690
[3] Patent: CN106892948, 2017, A. Location in patent: Paragraph 0188; 0189; 0190; 0191
[4] Helvetica Chimica Acta, 1938, vol. 21, p. 263,267
[5] Nucleosides, Nucleotides and Nucleic Acids, 2001, vol. 20, # 4-7, p. 703 - 706

1,2-O-Isopropylidene-a-L-xylofuranose synthesis

Synthesis of 1,2-O-Isopropylidene-a-L-xylofuranose from α-L-Xylofuranose,1,2:3,5-bis-O-(1-Methylethylidene)-

1,2-O-Isopropylidene-a-L-xylofuranose Preparation Products And Raw materials

Raw materials

L-Xylofuranose (9CI) α-L-Xylofuranose,1,2:3,5-bis-O-(1-Methylethylidene)- L-xylose L-Arabinose Hydrochloric acid

Acetone Water

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Preparation Products

Morpholine (3aS,5R,6S,6aS)-6-hydroxy-2,2-diMethyltetrahydrofuro[2,3-d][1,3]dioxole-5-carboxylate

1,2-O-Isopropylidene-a-L-xylofuranose Suppliers

Global( 90)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	info@dakenam.com	China	13619	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29837	58
Jinan Samuel Pharmaceutical CO., Ltd	0531-88821801 15192360884	605818151@qq.com	CHINA	124	58
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	8497	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19552	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Neostar United (Changzhou) Industrial Co., Ltd.	+86-0519-85551759 +8613506123987	marketing1@neostarunited.com	China	8830	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6312	58
Shanghai UCHEM Inc.	+862156762820 +86-13564624040	sales@myuchem.com	China	8553	58
Wuhan Fortuna Chemical Co., Ltd	+86-027-59207850 +86-13986145403;	info@fortunachem.com	China	6009	58

Supplier	Advantage
Shanghai Daken Advanced Materials Co.,Ltd	58
career henan chemical co	58
Jinan Samuel Pharmaceutical CO., Ltd	58
Jinan Carbotang Biotech Co.,Ltd.	58
BOC Sciences	58
Alchem Pharmtech,Inc.	58
Neostar United (Changzhou) Industrial Co., Ltd.	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	58
Shanghai UCHEM Inc.	58
Wuhan Fortuna Chemical Co., Ltd	58

View Lastest Price from 1,2-O-Isopropylidene-a-L-xylofuranose manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-01-15	1,2-O-Isopropylidene-α-L-xylofuranose 114861-22-2	US $0.00 / G	1G	98%min	30kg/month	WUHAN FORTUNA CHEMICAL CO., LTD
	2019-09-05	1,2-O-Isopropylidene-a-L-xylofuranose 114861-22-2	US $6.00 / KG	1KG	95%-98%	100	Career Henan Chemical Co

1,2-O-Isopropylidene-α-L-xylofuranose
114861-22-2
US $0.00 / G
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

1,2-O-Isopropylidene-a-L-xylofuranose
114861-22-2
US $6.00 / KG
95%-98%
Career Henan Chemical Co

114861-22-2(1,2-O-Isopropylidene-a-L-xylofuranose)Related Search:

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1,2:3,5-Di-O-isopropylidene-alpha-D-xylofuranose Diacetone L-sorbose 2,3:4,6-Di-O-isopropylidene-2-keto-L-gulonicacidmonohydrate DIKEGULAC ACID DIKEGULAC DIHYDRAT

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1,2-O-Isopropylidene-a-L-xylofuranose 1,2-O-Isopropylidene-alpha-L-xylofuranose α-L-Xylofuranose, 1,2-O-(1-Methylethylidene)- (3AS,5S,6R,6AS)-5-(HYDROXYMETHYL)-2,2-DIMETHYL-3A,5,6,6A-TETRAHYDROFURO[2,3-D][1,3]DIOXOL-6-OL 1,2-O-isopropylidene-α-L-xylofuranose SOTA-002 a-L-Xylofuranose,1,2-O-(1-methylethylidene)- 2,3,5-Tri-O-benzoyl-α-D-arabinofuranosyl Bromide 1,2-O-Isopropylidene-L-D-xylofuranose 1,2-O-Isopropylidene-α-L-xylofuranose 114861-22-2