14-Ethyl-9-(1-(hexyloxy)ethyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbine propanoic acid
- CAS No.
- 149402-51-7
- Chemical Name:
- 14-Ethyl-9-(1-(hexyloxy)ethyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbine propanoic acid
- Synonyms
- Photochlor;Sulcardine;Photochlor (HPPH);Photochlor (HTTP);Photochlor Photochlor;Inhibitor,HPPH,inhibit;3-Devinyl-3-(1'-hexyloxy)ethylpyropheophorbide A;2-(1-hexyloxyethyl)-2-devinyl pyropheophorbide-a;14-Ethyl-9-(1-(hexyloxy)ethyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbine propanoic acid;14-Ethyl-9-(1-(hexyloxy)ethyl)-4,8,13,18-tetramethyl-20-oxo-4-phorbine propanoic acid
- CBNumber:
- CB31238726
- Molecular Formula:
- C39H48N4O4
- Molecular Weight:
- 636.82
- MDL Number:
- MFCD11040935
- MOL File:
- 149402-51-7.mol
- MSDS File:
- SDS
Boiling point | 992.5±65.0 °C(Predicted) |
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Density | 1.184 |
storage temp. | Sealed in dry,Room Temperature |
solubility | DMSO:3.0(Max Conc. mg/mL);4.7(Max Conc. mM) |
form | A crystalline solid |
FDA UNII | DOB7Y3RSX0 |
NCI Drug Dictionary | Photochlor |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS05,GHS07,GHS08 |
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Signal word | Danger | |||||||||
Hazard statements | H302-H315-H318-H334-H317-H341-H361-H370-H335-H413 | |||||||||
Precautionary statements | P201-P202-P260-P264-P270-P272-P273-P280-P284-P301+P312-P302+P352-P304+P341-P305+P351+P338-P310-P308+P313-P321-P330-P362+P364-P333+P313-P342+P311-P363-P405-P501 | |||||||||
NFPA 704 |
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14-Ethyl-9-(1-(hexyloxy)ethyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbine propanoic acid price More Price(8)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Cayman Chemical | 20611 | HPPH ≥98% (mixture of epimers) | 149402-51-7 | 1mg | $49 | 2024-03-01 | Buy |
Cayman Chemical | 20611 | HPPH ≥98% (mixture of epimers) | 149402-51-7 | 5mg | $190 | 2024-03-01 | Buy |
Cayman Chemical | 20611 | HPPH ≥98% (mixture of epimers) | 149402-51-7 | 10mg | $356 | 2024-03-01 | Buy |
Cayman Chemical | 20611 | HPPH ≥98% (mixture of epimers) | 149402-51-7 | 25mg | $770 | 2024-03-01 | Buy |
TRC | P365010 | Photochlor | 149402-51-7 | 5mg | $175 | 2021-12-16 | Buy |
14-Ethyl-9-(1-(hexyloxy)ethyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbine propanoic acid Chemical Properties,Uses,Production
Description
HPPH is a chlorin that acts as a photosensitizer in photodynamic therapy (PDT) when stimulated with light at 655 nm. When administered systemically, HPPH accumulates in tumor cells and, when stimulated with light in the presence of oxygen, reactive oxygen species (ROS) are generated, leading to necrosis within the tumor. HPPH, at a dose of 0.5 mg/kg, increases survival in a nude rat model of glioma. It works synergistically with gemcitabine in several pancreatic cancer cell lines to induce cell death.
Uses
Photochlor is an anticancer photodynamic therapy drug that triggers multiple drug release and tumor killing cells in mouse breast cancer xenograft. Also functions as a photochlor-mediated photodynamic therapy for non-small cellular lung cancer treatment in murine model.
14-Ethyl-9-(1-(hexyloxy)ethyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbine propanoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9348 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
Biochempartner | 0086-13720134139 | candy@biochempartner.com | CHINA | 967 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
Jurong Coupling Biotechnology Co., Ltd. | 13656108824 | coupling278191416@hotmail.com | CHINA | 184 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 47465 | 58 |
career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 12477 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10326 | 58 |
View Lastest Price from 14-Ethyl-9-(1-(hexyloxy)ethyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbine propanoic acid manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2021-12-14 | Photochlor Photochlor
149402-51-7
|
US $10.00 / g/Bag | 10g | 99 | 100KG | Wuhan Demeikai Biotechnology Co., Ltd | ||
2020-01-03 | 14-Ethyl-9-(1-(hexyloxy)ethyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbine propanoic acid
149402-51-7
|
US $6.60 / KG | 1KG | 97%-99% | 1kg -1000kg | Career Henan Chemical Co |
- Photochlor Photochlor
149402-51-7
- US $10.00 / g/Bag
- 99
- Wuhan Demeikai Biotechnology Co., Ltd
- 14-Ethyl-9-(1-(hexyloxy)ethyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbine propanoic acid
149402-51-7
- US $6.60 / KG
- 97%-99%
- Career Henan Chemical Co