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HEXAMETHONIUM CHLORIDE

HEXAMETHONIUM CHLORIDE structure

CAS No.: 60-25-3

Chemical Name:: HEXAMETHONIUM CHLORIDE

Synonyms: depressin;hexonchloride;hiohexchloride;hexonechloride;esomidchloride;methiumchloride;chloor-hexaviet;bistriumchloride;hestriumchloride;hexametonchloride

CBNumber:: CB3125713

Molecular Formula:: C12H30Cl2N2

Molecular Weight:: 273.29

MDL Number:: MFCD00031563

MOL File:: 60-25-3.mol

MSDS File:: SDS

Last updated:2023-06-08 17:06:36

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HEXAMETHONIUM CHLORIDE Properties

Melting point	292°C(dec.)(lit.)
Boiling point	423.36°C (rough estimate)
Density	1.0558 (rough estimate)
refractive index	1.6400 (estimate)
solubility	H₂O: soluble
form	solid (hygroscopic)
color	white
Water Solubility	almost transparency
BRN	3714806
CAS DataBase Reference	60-25-3
FDA UNII	TIV4Q933FU
EPA Substance Registry System	1,6-Hexanediaminium, N,N,N,N',N',N'-hexamethyl-, dichloride (60-25-3)

SAFETY

Risk and Safety Statements

WGK Germany	3
RTECS	BQ8650000
HS Code	2923.90.0100

HEXAMETHONIUM CHLORIDE price More Price(10)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	H2138	Hexamethonium chloride solid (hygroscopic)	60-25-3	5g	$33.9	2024-03-01	Buy
Sigma-Aldrich	H2138	Hexamethonium chloride solid (hygroscopic)	60-25-3	25g	$84	2024-03-01	Buy
TCI Chemical	H0090	Hexamethonium Chloride Dihydrate >99.0%(T)	60-25-3	25g	$99	2023-01-07	Buy
TCI Chemical	H0090	Hexamethonium Chloride Dihydrate >99.0%(T)	60-25-3	100g	$249	2023-01-07	Buy
TCI Chemical	H0090	Hexamethonium Chloride Dihydrate >99.0%(T)	60-25-3	500g	$754	2023-01-07	Buy

Product number	Packaging	Price	Buy
H2138	5g	$33.9	Buy
H2138	25g	$84	Buy
H0090	25g	$99	Buy
H0090	100g	$249	Buy
H0090	500g	$754	Buy

HEXAMETHONIUM CHLORIDE Chemical Properties,Uses,Production

Chemical Properties

White, crystalline, hygroscopic powder; faint odor. Very soluble in water; soluble in alcohol, methanol, and n-propanol; insoluble in chloroform and ether. Available commercially as unhydrated form or as dihydrate.

Uses

Hexamethonium chloride has been used to block the responses of nicotinic receptors towards it agonists. It has also been used to study the mechanosensitivity of viscerofugal neurons.

Uses

Medicine (antihypertensive).

Uses

Hexamethonium Chloride is a ganglionic nicotinic receptor blocker.

General Description

Nicotinic acetylcholine receptor (nAChR) forms a ligand-gated ion channel made up of four different subunits. Each subunit contains an extracellular amino-terminal domain (hydrophilic) and carboxylic terminal domain and four transmembrane domains. nAChR is an allosteric and transmembrane protein localized to the neuromuscular junction.

Biochem/physiol Actions

Hexamethonium chloride preferentially blocks nicotinic receptors at autonomic ganglia, crosses blood-brain barrier only at high doses. Nicotinic acetylcholine receptor (nAChR) is responsible for cognitive functions. Blocking this receptor results in cognitive impairment. nAChR antagonist is used to study the effect of loss of receptor function. Hexamethonium has a peripheral action over blocking the nAChR.

HEXAMETHONIUM CHLORIDE synthesis

Synthesis of HEXAMETHONIUM CHLORIDE from 1,6-Dichlorohexane and Trimethylamine

HEXAMETHONIUM CHLORIDE Preparation Products And Raw materials

Raw materials

1,6-Dichlorohexane Trimethylamine

Preparation Products

HEXAMETHONIUM CHLORIDE Suppliers

Global( 96)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58
Chemsigma International Co., Ltd.	+86-18136843612 +86-19951791336	info@chemsigma.com	China	963	58
Alfa Chemistry		info@alfa-chemistry.com	United States	2344	58
Wuhan Fortuna Chemical Co., Ltd	+86-27-59207850 +86-13986145403	info@fortunachem.com	China	5988	58
Dayang Chem (Hangzhou) Co.,Ltd.	571-88938639 +8617705817739	info@dycnchem.com	CHINA	52867	58
CD Chemical Group Limited	+8615986615575	info@codchem.com	China	20356	58
weifang runzhong fine chemical co., ltd	536-7868377 +8618653686003	sq@runzhongchem.com	China	187	58
Hebei Duling International Trade Co. LTD	+8618032673083	sales05@hbduling.cn	China	15745	58
GIHI CHEMICALS CO.,LIMITED	+8618058761490	info@gihichemicals.com	China	49999	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58

Supplier	Advantage
Career Henan Chemica Co	58
Chemsigma International Co., Ltd.	58
Alfa Chemistry	58
Wuhan Fortuna Chemical Co., Ltd	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
CD Chemical Group Limited	58
weifang runzhong fine chemical co., ltd	58
Hebei Duling International Trade Co. LTD	58
GIHI CHEMICALS CO.,LIMITED	58
Aladdin Scientific	58

View Lastest Price from HEXAMETHONIUM CHLORIDE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2023-01-18	Hexamethonium chloride 60-25-3	US $0.00 / KG	1KG	98%min	30tons/month	WUHAN FORTUNA CHEMICAL CO., LTD
2023-01-16	HEXAMETHONIUM CHLORIDE 60-25-3	US $9.90 / kg	1kg	99%	5000 tons	Hebei Duling International Trade Co. LTD
2022-10-11	HEXAMETHONIUM CHLORIDE 60-25-3	US $0.00-0.00 / kg	1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.

Hexamethonium chloride
60-25-3
US $0.00 / KG
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

HEXAMETHONIUM CHLORIDE
60-25-3
US $9.90 / kg
99%
Hebei Duling International Trade Co. LTD

HEXAMETHONIUM CHLORIDE
60-25-3
US $0.00-0.00 / kg
98%
Henan Aochuang Chemical Co.,Ltd.

HEXAMETHONIUM CHLORIDE Spectrum

HEXAMETHONIUM CHLORIDE(60-25-3)MS HEXAMETHONIUM CHLORIDE(60-25-3)¹HNMR HEXAMETHONIUM CHLORIDE(60-25-3)IR1 HEXAMETHONIUM CHLORIDE(60-25-3)IR2

60-25-3(HEXAMETHONIUM CHLORIDE)Related Search:

Dodecyltrimethylammonium Bromide Hexane Ammonium chloride HEXAMETHONIUM CHLORIDE DIHYDRATE triclobisonium chloride

dodeconium Poly(diallyldimethylammonium chloride) HEXAMETHONIUM CHLORIDE

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6-hexanediaminium,n,n,n,n’,n’,n’-hexamethyl-dichloride hexonchloride hexonechloride hiohexchloride methiumchloride A,W-BIS(TRIMETHYLAMMONIUM)HEXANE DICHLORIDE HEXAMETHYLENEBIS[TRIMETHYLAMMONIUM CHLORIDE] HEXAMETHONIUM CHLORIDE HEXAMETHONIUM DICHLORIDE HEXANE-1,6-BIS[TRIMETHYLAMMONIUM CHLORIDE] ALPHA OMEGA-BIS(TRIMETHYLAMMONIUM)HEXANE DICHLORIDE n,n,n,n',n',n'-hexamethyl-1,6-hexanediammonium dichloride bistriumchloride chloor-hexaviet depressin esomidchloride hestriumchloride hexamethioniumchloride hexamethylenebis(trimethyl-ammoniudichloride hexametonchloride Hexamethonium dichloride, N,N,N,Nμ,Nμ,Nμ-Hexamethyl-1,6-hexanediaminium dichloride, N,N,N,Nμ,Nμ,Nμ-Hexamethylhexamethylenediammonium dichloride Hexamethylenebis(trimethylaminium)·dichloride N,N,N,N',N',N'-Hexamethyl-1,6-hexanediaminium dichloride N,N,N,N',N',N'-Hexamethylhexamethylenediammonium dichloride Hexamethylenebis(trimethylammonium Chloride) N,N,N,N',N',N'-Hexamethyl-1,6-hexanediammonium Dichloride Hexane-1,6-bis(trimethylammonium Chloride) HexaMethoniuM Chloride N1,N1,N1,N6,N6,N6-hexaMethylhexane-1,6-diaMiniuM chloride 1,6-Hexanediaminium, N1,N1,N1,N6,N6,N6-hexamethyl-, chloride (1:2) HexamethoniumChlorideDihydrate> Trimethyl-[6-(trimethylazaniumyl)hexyl]azanium Dichloride Hexamethonium Chloride hydrate 60-25-3 CH33NClCH26NClCH33 C12H30Cl2N2 C12H30Cl2N22H2O Ammonium Chlorides (Quaternary) Quaternary Ammonium Compounds