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N-methylisatoic anhydride

CAS No.
10328-92-4
Chemical Name:
N-methylisatoic anhydride
Synonyms
MIA;NSC439;NSC 439;NSC-439;AKOS 226;AI300638;NSC 76087;MIA human;4-dithiin;AI3 00638
CBNumber:
CB3126220
Molecular Formula:
C9H7NO3
Molecular Weight:
177.16
MDL Number:
MFCD00006815
MOL File:
10328-92-4.mol
MSDS File:
SDS
Last updated:2023-06-08 17:06:34

N-methylisatoic anhydride Properties

Melting point 165 °C (dec.)(lit.)
Boiling point 309.06°C (rough estimate)
Density 1.3312 (rough estimate)
vapor density 6.1 (vs air)
refractive index 1.5200 (estimate)
storage temp. Inert atmosphere,Room Temperature
solubility Soluble in DMSO
pka -2.24±0.20(Predicted)
Sensitive Moisture Sensitive
CAS DataBase Reference 10328-92-4(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 7SWE4B4CY2
EPA Substance Registry System 2H-3,1-Benzoxazine-2,4(1H)-dione, 1-methyl- (10328-92-4)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-37/39
WGK Germany  3
RTECS  DM3140000
TSCA  Yes
HS Code  2934.99.4400
NFPA 704
0
2 0

N-methylisatoic anhydride price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 129887 N-Methylisatoic anhydride technical, 90% 10328-92-4 100g $89.2 2024-03-01 Buy
TCI Chemical M0743 N-Methylisatoic Anhydride 10328-92-4 5G $102 2024-03-01 Buy
TCI Chemical M0743 N-Methylisatoic Anhydride >98.0%(GC) 10328-92-4 25g $400 2024-03-01 Buy
Alfa Aesar B24099 N-Methylisatoic anhydride, tech. 90% 10328-92-4 100g $58.65 2024-03-01 Buy
TRC M293158 1-Methyl-1H-benzo[d][1,3]oxazine-2,4-dione 10328-92-4 500mg $55 2021-12-16 Buy
Product number Packaging Price Buy
129887 100g $89.2 Buy
M0743 5G $102 Buy
M0743 25g $400 Buy
B24099 100g $58.65 Buy
M293158 500mg $55 Buy

N-methylisatoic anhydride Chemical Properties,Uses,Production

Chemical Properties

brownish chunks

Uses

N-Methylisatoic anhydride is a 2'-OH selective acylation agent of RNAs, and is widely used for resolving secondary RNA structures using the SHAPE (Selective 2'-Hydroxyl Acylation Analyzed by Primer Extension) technology.

Definition

ChEBI: N-methylisatoic anhydride is a 3,1-benzoxazin-1,4-dione having an N-methyl substituent.

Application

N-Methylisatoic anhydride was first condensed with ethanolamine to give N-(2-hydroxyethyl)-2-methylaminobenzamide. Cyclization of the latter with ethyl pyruvate gave quinazoline derivatives which, upon hydrolysis and dehydrative cyclization with l-methyl-2-chloropyridinium iodide, afforded the l,4-oxazines[3,4-]quinazoline.

N-methylisatoic anhydride Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 153)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32480 60
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
Accela ChemBio Inc.
(+1)-858-699-3322 info@accelachem.com United States 19965 58
Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
Zhengzhou Alfa Chemical Co.,Ltd
+8618530059196 sale04@alfachem.cn China 12468 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Shanghai Rlavie Technology Co ltd
+86-021-67759270 +8617717059219 sales@rlavie.com China 1030 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418671 sales@tnjchem.com China 34572 58
Alfa Chemistry
info@alfa-chemistry.com United States 2344 58

View Lastest Price from N-methylisatoic anhydride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N-Methylisatoic anhydride pictures 2022-01-04 N-Methylisatoic anhydride
10328-92-4
US $0.00-0.00 / KG 1g 98%minHPLC 500kgs/month Shanghai Rlavie Technology Co ltd
N-METHYLISATOIC ANHYDRIDE pictures 2019-07-06 N-METHYLISATOIC ANHYDRIDE
10328-92-4
US $100.00 / KG 1KG 99% 20kg Career Henan Chemical Co
N-METHYLISATOIC ANHYDRIDE pictures 2019-07-06 N-METHYLISATOIC ANHYDRIDE
10328-92-4
US $20.00 / KG 1KG 995 20kg Career Henan Chemical Co
N-methyl isotoic anhydride Isatoic anhydride, N-Methyl- N-Methylisatioc anhydride 1-methyl-1H-benzo[d][1,3]oxazine-2,4-dione 1-Methyl-1,2-dihydro-4H-3,1-benzoxazine-2,4-dione 1-Methyl-1H-3,1-benzoxazine-2,4-dione 1-Methyl-4H-3,1-benzoxazine-2(1H),4-dione N-Methylisatoic anhydride,90%,tech. N-Methylisatoic Anhydride MIA N-METHYLISATOIC ANHYDRIDE TIMTEC-BB SBB000196 1-Methyl-2H-3,1-benzoxazine-2,4(1H)-dione 2H-3,1-Benzoxazine-2,4(1H)-dione, 1-methyl- 4(1h)-dione,1-methyl-2h-1-benzoxazine-2 N-Methyl ia n-methylia N-Methyl-N-carboxyanthranilic anhydride N-METHYLISATOIC ANHYDRIDE, TECH., 90% N-Methylisatoicanhydride,tech.,90% AKOS 226 1-Methyl-4H-3,1-benzoxazine-2,4(1H)dione N-Methylisatoic acid anhydride NSC 76087 N-Methylisatoic anhydride technical, 90% Melanoma-derived growth regulatory protein precursor MIA human N-MethylisatoicAnhydride> 10-Dithiaanthracene 4-dithiin AI3 00638 AI300638 AI3-00638 dibenzo-1 NSC 439 NSC439 NSC-439 N-Methylisatoic anhydride (NMIA) 1-methyl-3,1-benzoxazine-2,4-dione 10328-92-4 10328-92-7 Monomers Polymer Science pharmacetical Anhydride Monomers