ANTI-LEPTIN
- CAS No.
- Chemical Name:
- ANTI-LEPTIN
- Synonyms
- Anti-OB;Anti-OBS;Anti-OSF-4;Anti-CAD11;Anti-CDHOB;ANTI-LEPTIN;ANTI-HUMAN OB;ANTI-MOUSE OB;ANTI-MURINE OB;ANTI-HUMAN LEPTIN
- CBNumber:
- CB3138469
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00803408
- MOL File:
- Mol file
ANTI-LEPTIN price More Price(2)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SAB2101335 | Anti-LEP antibody produced in rabbit affinity isolated antibody | 100μL | $524 | 2024-03-01 | Buy | |
| Sigma-Aldrich | L3410 | Anti-Leptin antibody produced in rabbit affinity isolated antibody, buffered aqueous solution | 0.2ML | $544 | 2023-06-20 | Buy |
ANTI-LEPTIN Chemical Properties,Uses,Production
Uses
Anti-Leptin antibody produced in rabbit has been used in:
- western blotting
- immunohistochemistry
- immunocytochemistry
- enzyme linked immunosorbent assay (ELISA)
General Description
The gene for leptin (LEP) is mapped to the human chromosome 7q32.1. The encoded protein is a non-glycosylated polypeptide, primarily produced and secreted by the mature adipocytes. Leptin is expressed in white adipose tissue, fetal tissues, skeletal muscle, chondrocytes, gastric chief cells, the placenta, ovary, and many immune cells. It is absent or expressed at extremely low levels in other adult tissues. Human leptin is 85% identical to mouse leptin and 84% identical to rat leptin, while mouse and rat exhibit 96% identity in their leptin molecules.
Biochem/physiol Actions
Leptin is a hormone secreted by adipocytes and regulates energy homeostasis, inflammation and neuroendocrine processes, synaptic formation and memory condensation. The physiological effects of leptin are mediated by leptin receptors, ObR and LepR. Leptin is the key regulator of obesity and acts directly on neuronal networks to regulate feeding, metabolism and gastric mobility. The pathways that mediate the effect of leptin are Janus kinase (JAK)/signal transducer and activator of transcription (STAT), phosphoinositide 3-kinase (PI3K) and c-Jun N-terminal kinase (JNK).
ANTI-LEPTIN Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-LEPTIN Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Shanghai guandao biology engineering co., ltd | 18818239863 18818239863 | 3171921642@qq.com | China | 8884 | 58 |
| Supplier | Advantage |
|---|---|
| Sigma-Aldrich | 80 |
| Shanghai guandao biology engineering co., ltd | 58 |