ChemicalBook >> CAS DataBase List >>4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane
4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane
![4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane Structure](CAS/GIF/57280-22-5.gif)
- CAS No.
- 57280-22-5
- Chemical Name:
- 4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane
- Synonyms
- 0]Octane;4-Dimethyl-3;8-trioxabic-yclo[5;Trioxabicyclooctane;Gadobutrol Impurity 49;2-Ethoxyethyl ether 112-36-7;4,4-Dimethyl-3,5,8-trioxabicyclo[5.1.]octane;4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane;3,5,8-Trioxabicyclo[5.1.0]octane, 4,4-diMethyl-;4,4-diMethyl-3,5,8-trioxabicyclo[5.1.0]octane(EP2)
- CBNumber:
- CB31452526
- Molecular Formula:
- C7H12O3
- Molecular Weight:
- 144.17
- MDL Number:
- MFCD16621162
- MOL File:
- 57280-22-5.mol
- MSDS File:
- SDS
Last updated:2024-03-26 14:13:49
| Boiling point | 179℃ |
|---|---|
| Density | 1.071 |
| refractive index | 1.4560 to 1.4600 |
| Flash point | 56℃ |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| form | clear liquid |
| color | Colorless to Light yellow to Light orange |
| FDA UNII | UH2578TWH3 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H317-H319 | |||||||||
| Precautionary statements | P261-P271-P280 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36-43 | |||||||||
| Safety Statements | 26-36/37-24/25 | |||||||||
| HS Code | 29329990 | |||||||||
| NFPA 704 |
|
4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | D5200 | 4,4-Dimethyl-3,5,8-trioxabicyclo[5.1.0]octane >95.0%(GC) | 57280-22-5 | 1g | $30 | 2024-03-01 | Buy |
| TCI Chemical | D5200 | 4,4-Dimethyl-3,5,8-trioxabicyclo[5.1.0]octane >95.0%(GC) | 57280-22-5 | 5g | $108 | 2024-03-01 | Buy |
| TRC | D480778 | 4,4-Dimethyl-3,5,8-trioxabicyclo[5.1.0]octane | 57280-22-5 | 25g | $165 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD29424 | 4,4-Dimethyl-3,5,8-trioxabicyclo[5,1,0]octane | 57280-22-5 | 25g | $125 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD29424 | 4,4-Dimethyl-3,5,8-trioxabicyclo[5,1,0]octane | 57280-22-5 | 50g | $200 | 2021-12-16 | Buy |
4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane Chemical Properties,Uses,Production
Chemical Properties
Clear colorless to yellow liquid
Uses
4,4-Dimethyl-3,5,8-trioxabicyclo[5.1.0]octane is used in the CO2-mediated formation of chiral carbamates from meso-epoxides via polycarbonate intermediates and amine nucleophiles, which opens up a wide a wide range of CO2-based carbamate scaffolds with excellent yields and 99% enantiomeric excess.
Application
4, 4-dimethyl-3,5, 8-trioxane [5,1,0] octane is a key intermediate in the preparation of gadobinol. As a meso epoxide, it could be used to obtain optically pure ABT derivatives through Ti(IV)/BINOL catalyzed asymmetric aminolysis[1].
References
[1] Bao H, et al. Insight into the Mechanism of the Asymmetric Ring-Opening Aminolysis of 4,4-Dimethyl-3,5,8-trioxabicyclo[5.1.0]octane Catalyzed by Titanium/BINOLate/Water System: Evidence for the Ti(BINOLate)2-Bearing Active Catalyst Entities and the Role of Water. Journal of the American Chemical Society, 2008; 130: 10116–10127.
Synthesis of 4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane from 2,2-Dimethyl-1,3-dioxacyclohept-5-ene
4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane Preparation Products And Raw materials
Global( 240)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Xilinglab Co., Ltd. | +8618381337976 | bd@xilinglab.com | China | 86 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 7786 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15928 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3012 | 60 |
| Jiangsu Qingquan Chemical Co., Ltd. | +86-571-86589381,86589382,86589383 | sales1@qqpharm.com | CHINA | 154 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | sales@sdzschem.com | China | 2931 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 6992 | 58 |
View Lastest Price from 4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
![4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane pictures](/ProductImageEN/2024-03/Small/faa3d7a7-53b9-4df4-a7e7-359796f25232.gif) |
2024-03-26 | 4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane
57280-22-5
|
US $30.00-0.80 / kg | 1kg | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
![4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]octane pictures](/ProductImageEN/2022-11/Small/5651e072-6068-4ce8-830e-802526832be7.png) |
2022-11-15 | 4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]octane
57280-22-5
|
US $0.00-0.00 / KG | 1KG | ≥98% | 1-1000KGS | Changzhou Rokechem Technology Co., Ltd. | |
![4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane pictures](/ProductImageEN/2022-09/Small/acc72363-b541-4575-86f7-2fe5d6c7abf2.png) |
2022-09-06 | 4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane
57280-22-5
|
US $0.00 / KG | 25KG | 97% | 1tone | Henan Aochuang Chemical Co.,Ltd. |
-
- 4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane
57280-22-5
- US $30.00-0.80 / kg
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]octane
57280-22-5
- US $0.00-0.00 / KG
- ≥98%
- Changzhou Rokechem Technology Co., Ltd.
-
- 4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane
57280-22-5
- US $0.00 / KG
- 97%
- Henan Aochuang Chemical Co.,Ltd.
4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane
3,5,8-Trioxabicyclo[5.1.0]octane, 4,4-diMethyl-
4,4-diMethyl-3,5,8-trioxabicyclo[5.1.0]octane(EP2)
4,4-Dimethyl-3,5,8-trioxabic-yclo[5.1.0]octane(DTC-octane)
Gadobutrol Impurity 49
4 4-DIMETHYL-3 5 8-TRIOXABICYCLO (5.1.0)OCTANE TOBO
0]Octane
4-Dimethyl-3
8-trioxabic-yclo[5
4,4-Dimethyl-3,5,8-trioxabicyclo[5.1.]octane
China biggest manufacturer 4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane 57280-22-5
2-Ethoxyethyl ether 112-36-7
3,5,8-Trioxabicyclo[5.1.0]octane, 4,4-dimethyl- 4,4-Dimethyl-3,5,8-trioxabicyclo[5.1.0]octane
Trioxabicyclooctane
57280-22-5
572780-22-5
57280-22-5