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Ammothamnine

Ammothamnine Structure
Ammothamnine structure
CAS No.
16837-52-8
Chemical Name:
Ammothamnine
Synonyms
OXYMATRINE;Kurainone;cis-matrine;ammothamnine;MATRINE OXIDE;OXYMATRINE(P);Oxymatrine,(S);Pachycarpidine;Oxymatrine CRS;matrine n-oxide
CBNumber:
CB3150469
Molecular Formula:
C15H24N2O2
Molecular Weight:
264.36
MDL Number:
MFCD00210339
MOL File:
16837-52-8.mol
Last updated:2024-04-23 16:18:34
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Ammothamnine Properties

Melting point 208℃
storage temp. Inert atmosphere,2-8°C
solubility methanol: soluble10mg/mL, clear, colorless
pka 4.87±0.20(Predicted)
form powder
color white to off-white
Stability Hygroscopic
InChIKey XVPBINOPNYFXID-LHDUFFHYSA-N
FDA UNII 85U4C366QS

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264b-P270-P301+P312-P330-P403-P501c
Hazard Codes  Xn
Risk Statements  22-20/22
Safety Statements  24/25
WGK Germany  3
RTECS  OQ1770000
HS Code  29399990
NFPA 704
0
2 0

Ammothamnine price More Price(36)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich Y0002015 Oxymatrine European Pharmacopoeia (EP) Reference Standard 16837-52-8 Y0002015 $150 2023-06-20 Buy
Sigma-Aldrich PHL89748 Oxymatrine phyproof? Reference Substance 16837-52-8 25MG $272 2023-06-20 Buy
Alfa Aesar H37340 Oxymatrine 98% 16837-52-8 250mg $129.65 2024-03-01 Buy
Alfa Aesar H37340 Oxymatrine 98% 16837-52-8 1g $369.65 2024-03-01 Buy
Cayman Chemical 14915 Oxymatrine ≥98% 16837-52-8 50mg $49 2024-03-01 Buy
Product number Packaging Price Buy
Y0002015 Y0002015 $150 Buy
PHL89748 25MG $272 Buy
H37340 250mg $129.65 Buy
H37340 1g $369.65 Buy
14915 50mg $49 Buy

Ammothamnine Chemical Properties,Uses,Production

Description

Oxymatrine is a natural alkaloid isolated from the root of S. flavescens, an herb used in traditional Chinese herbal medicine. It has antiviral properties, inhibiting the replication of hepatitis B alone and in combination with lamivudine. Oxymatrine also prevents fibrosis in a number of organs including liver, at least in part by interfering with TGF-β signaling. This compound also induces apoptosis in certain cancer cells and ameliorates inflammation by impairing the translocation of nuclear factors-κB.

Description

An alkaloid from Sophora angustifolia var. flavescens S. and Z., the bas'e crystal_x0002_lizes as the monohydrate having the lower melting point given above. It is dextrorotatory with [α]19D + 47.7° (EtOH) and yields crystalline salts and derivatives: hydrobromide, m.p. 21SoC; aurichloride, m.p. 207°C (dec.); perchlorate, m.p. 240°C (dec.); picrate, m.p. 21SoC and the methochloride aurichloride, m.p. 18SoC (dec.). Ochiai and Ito have shown that it is formed by the action of hydrogen peroxide on Matrine (q.v.), indicating that its structure is matrine-N-oxide.

Uses

Oxymatrine is a an anti-tumor agent triggering apoptosis in human leukemia cells.

Uses

antifungal, hepatoprotectant

Definition

ChEBI: Ammothamnine is an alkaloid and a tertiary amine oxide.

References

Kondo et al., Arch. Pharm., 275,493 (1937)
Ochiai, Ito., Ber., 81,938 (1938)

Ammothamnine Preparation Products And Raw materials

Raw materials

Preparation Products

Ammothamnine Suppliers

Global( 470)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Mojin Biotechnology Co., Ltd 		+8613288715578 sales@hbmojin.com China 12457 58
Henan Bao Enluo International TradeCo.，LTD 		+86-17331933971 +86-17331933971 deasea125996@gmail.com China 2503 58
Shaanxi Haibo Biotechnology Co., Ltd 		+undefined18602966907 qinhe02@xaltbio.com China 1000 58
Ouhuang Engineering Materials (Hubei) Co., Ltd 		+8617702722807 admin@hbouhuang.com China 1175 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21695 55
Hangzhou FandaChem Co.,Ltd. 		008657128800458; +8615858145714 fandachem@gmail.com China 9348 55
Rixing Chemical CO.,LTD 		+86-13237129059 -13237129059 sales@rixingchemi.com CHINA 229 55
Nanjing Finetech Chemical Co., Ltd. 		025-85710122 17714198479 sales@fine-chemtech.com CHINA 885 55
Shanghai Zheyan Biotech Co., Ltd. 		18017610038 zheyansh@163.com CHINA 3620 58
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29914 58
Supplier Advantage
Hebei Mojin Biotechnology Co., Ltd 		58
Henan Bao Enluo International TradeCo.，LTD 		58
Shaanxi Haibo Biotechnology Co., Ltd 		58
Ouhuang Engineering Materials (Hubei) Co., Ltd 		58
Henan Tianfu Chemical Co.,Ltd. 		55
Hangzhou FandaChem Co.,Ltd. 		55
Rixing Chemical CO.,LTD 		55
Nanjing Finetech Chemical Co., Ltd. 		55
Shanghai Zheyan Biotech Co., Ltd. 		58
career henan chemical co 		58

View Lastest Price from Ammothamnine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
oxymatrine pictures 2024-04-23 oxymatrine
16837-52-8
 US $15.00 / kg 1kg 99.912% 10ton Ouhuang Engineering Materials (Hubei) Co., Ltd
Oxymatrine pictures 2024-04-23 Oxymatrine
16837-52-8
 US $0.00 / KG 1KG ≥98% HPLC 1000KG Changsha Staherb Natural Ingredients Co., Ltd.
Ammothamnine pictures 2024-04-12 Ammothamnine
16837-52-8
 US $0.00 / kg 1kg 99% 2000ton Shaanxi Haibo Biotechnology Co., Ltd
  • oxymatrine pictures
  • oxymatrine
    16837-52-8
  • US $15.00 / kg
  • 99.912%
  • Ouhuang Engineering Materials (Hubei) Co., Ltd
  • Oxymatrine pictures
  • Oxymatrine
    16837-52-8
  • US $0.00 / KG
  • ≥98% HPLC
  • Changsha Staherb Natural Ingredients Co., Ltd.
  • Ammothamnine pictures
  • Ammothamnine
    16837-52-8
  • US $0.00 / kg
  • 99%
  • Shaanxi Haibo Biotechnology Co., Ltd

Ammothamnine Spectrum

Ammothamnine(16837-52-8)1HNMR

16837-52-8(Ammothamnine)Related Search:

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(Diethoxymethyl)diphenylphosphine oxide Rotundine Quercetin dihydrate

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1-oxide,(1-beta)-matridin-15-on 1H,5H,10H-Dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one, dodecahydro-, 4-oxide, (4R,7aS,13aR,13bR,13cS)- Ammothamnine Oxymatrine (4R,7aS,13aR,13bR,13cS)-dodecahydro-4-oxide-1H,5H,10H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one matrine,1-oxide matrine1beta-oxide ammothamnine (6AS,11AR,11BR,11CS)-3A-OXY-DODECAHYDRO-3A,7A-DIAZA-BENZO[DE]ANTHRACEN-8-ONE matrine n-oxide MATRINE OXIDE Kurainone OXYMATRINE, 98.0% BY HPLC Oxymatrine std. OXYMATRINE(P) Matridin-15-one,1-oxide, (1β)- Oxymatrine，Matrine N-oxide，Ammothamnine Matrine N-oxide. Ammothamnine. Pachycarpidine Oxymatrine,(S) Dodecahydro-1,8-dihydroxy-7,14-methano-4H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-4-one OxyMatrine(Matrine N-oxide) Pachycarpidine Oxymatrine, 98%, from Sophora flavescens Aiton Oxymatrine 16837-52-8 cis-matrine Oxymatrine CRS Oxymatrine Standard Ammothamnine USP/EP/BP (1R,2R,9S,13S,17S)-13-Oxido-7-aza-13-azoniatetracyclo[7.7.1.02,7.013,17]heptadecan-6-one OXYMATRINE (4S,41S,7aS,13aR,13bR)-10-Oxododecahydro-1H,5H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridine 4(41H)-oxide oxymatrine?pesticide Oxymatrine Marine (4S,41S,7aS,13aR,13bR)-10-Oxododecahydro-1H,5H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridine 4(41H)-oxide 16837-52-8 6837-52-8 C15H24N2O2 Pyrazoles Inhibitors reference standards from Chinese medicinal herbs (TCM). standardized herbal extract Plant extracts chemical reagent pharmaceutical intermediate phytochemical Plant extract Alkaloids Natural Plant Extract Pharmaceutical material and intermeidates 16837-52-8