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TALIPEXOLE

TALIPEXOLE
TALIPEXOLE structure
CAS No.
101626-70-4
Chemical Name:
TALIPEXOLE
Synonyms
Domin;Talipexol;TALIPEXOLE;Talipexolum;Talipexolum [latin];Talipexol [spanish];TALIPEXOLE USP/EP/BP;6-Allyl-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepin-2-amine;6-Allyl-2-amino-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepine;6-Allyl-5,6,7,8-tetrahydro-4H-[1,3]thiazolo[4,5-d]azepin-2-amine
CBNumber:
CB3153213
Molecular Formula:
C10H15N3S
Formula Weight:
209.31
MOL File:
101626-70-4.mol

TALIPEXOLE Properties

Boiling point:
364.6±37.0 °C(Predicted)
Density 
1.167±0.06 g/cm3(Predicted)
pka
7.22±0.20(Predicted)
FDA UNII
7AM2J46Z1Y

TALIPEXOLE Chemical Properties,Uses,Production

Description

Domin was launched in Japan for Parkinson's disease. The compound is readily accessible in two steps from I-allylhexahydro-4H-azepin4-one. Its antiparkinson activity resides in the fact that talipexole is a selective agonist for presynaptic dopamine D2 receptors with no D1 receptor activity. It is a clonidine-like α2-adrenoreptor agonist and has fewer GI side effects than bromocriptine the most widely used dopamine angonist. Also it is 70 times more potent than bromocriptine and has a more rapid onset of action. In addition to its anti-tremor activity there was a sedative effect but no emesis. The latter probably a result of talipexole's 5-HT3 receptor antagonistic activity. Its metabolites have no biological activity, there was no development of tolerence and its effect could be enhanced by L-dopa.

Originator

Boehringer Ingelheim (Germany)

brand name

Domin

TALIPEXOLE Preparation Products And Raw materials

Raw materials

Preparation Products


TALIPEXOLE Suppliers

Global( 31)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Target Molecule Corp
18019718960 781-999-5354
marketing@targetmol.com United States 19232 58
Shaanxi Dideu Medichem Co. Ltd
18192503167 +86-29-89586680
+86-29-88380327 1005@dideu.com CHINA 9938 58
Dideu Industries Group Limited
029-88380327
Service@dideu.com CHINA 30013 58
Amadis Chemical Company Limited
0086-571-89925085
0086-571-89925065 sales@amadischem.com China 132148 58
LGM Pharma 1-(800)-881-8210
615-250-9817 inquiries@lgmpharma.com United States 1938 70
BOC Sciences 16314854226
info@bocsci.com United States 21113 65
MedChemexpress LLC 609-228-6898
609-228-5909 sales@medchemexpress.com United States 4787 58
LETOPHARM LIMITED +86-21-5821 5861
+86-21-5106 2861 sales@letopharm.com China 2388 58
Musechem +1-800-259-7612
+1-800-259-7612 info@musechem.com United States 4665 60
Jinan blalong chemical co. LTD 2710913286@qq.com
1513643261@qq.com China 18596 58

View Lastest Price from TALIPEXOLE manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-06-04 TALIPEXOLE USP/EP/BP
101626-70-4
US $1.10 / g 1g 99.9% 100 Tons Min Dideu Industries Group Limited

101626-70-4(TALIPEXOLE)Related Search:


  • TALIPEXOLE
  • 5,6,7,8-Tetrahydro-6-(2-propenyl)-4H-thiazolo[4,5-d]azepin-2-amine
  • Domin
  • 6-Allyl-2-amino-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepine
  • 6-Allyl-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepin-2-amine
  • Talipexol
  • Talipexol [spanish]
  • Talipexolum
  • Talipexolum [latin]
  • 4H-Thiazolo[4,5-d]azepin-2-amine, 5,6,7,8-tetrahydro-6-(2-propen-1-yl)-
  • TALIPEXOLE USP/EP/BP
  • 6-Allyl-5,6,7,8-tetrahydro-4H-[1,3]thiazolo[4,5-d]azepin-2-amine
  • 101626-70-4
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