tert-Butyl (trans-3-(hydroxymethyl)cyclobutyl)carbamate
- CAS No.
- 167081-37-0
- Chemical Name:
- tert-Butyl (trans-3-(hydroxymethyl)cyclobutyl)carbamate
- Synonyms
- trans-1-(Boc-aMino)-3-(hy...;tert-Butyl (trans-3-(hydroxymethyl);trans-3-(Boc-amino)cyclobutanemethanol,97%;trans-3-(Boc-aMino)cyclobutaneMethanol, 97%;BUTYL TRANS-3-HYDROXYMETHYLCYCLOBUTYLCARBAMATE;trans-1-(Boc-aMino)-3-(hydroxyMethyl)cyclobutane;tert-butyl N-[3-(hydroxymethyl)cyclobutyl]carbamat;TERT-BUTYL TRANS-3-HYDROXYMETHYLCYCLOBUTYLCARBAMATE;tert-butyl (1r,3r)-3-(hydroxymethyl)cyclobutylcarbamate;trans-1-(Boc-amino)-3-(hydroxymethyl)cyclobutane - SB7652
- CBNumber:
- CB3158733
- Molecular Formula:
- C10H19NO3
- Molecular Weight:
- 201.26
- MDL Number:
- MFCD08166748
- MOL File:
- 167081-37-0.mol
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H302 | |||||||||
Precautionary statements | P280-P305+P351+P338 | |||||||||
HS Code | 2922500090 | |||||||||
NFPA 704 |
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tert-Butyl (trans-3-(hydroxymethyl)cyclobutyl)carbamate price More Price(23)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Alfa Aesar | H62719 | trans-3-(Boc-amino)cyclobutanemethanol 97% | 167081-37-0 | 250mg | $184.65 | 2024-03-01 | Buy |
Alfa Aesar | H62719 | trans-3-(Boc-amino)cyclobutanemethanol 97% | 167081-37-0 | 1g | $550.65 | 2024-03-01 | Buy |
Biosynth Carbosynth | FB53711 | Tert-Butyl Trans-3-Hydroxymethylcyclobutylcarbamate | 167081-37-0 | 500mg | $580 | 2021-12-16 | Buy |
Matrix Scientific | 089423 | tert-Butyl trans-3-hydroxymethylcyclobutylcarbamate | 167081-37-0 | 1g | $1183 | 2021-12-16 | Buy |
SynQuest Laboratories | 4256-1-27 | trans-1-(Boc-amino)-3-(hydroxymethyl)cyclobutane | 167081-37-0 | 5G | $1250 | 2021-12-16 | Buy |
tert-Butyl (trans-3-(hydroxymethyl)cyclobutyl)carbamate Chemical Properties,Uses,Production
Synthesis
To a stirred solution of methyl (1R,3R)-3-((tert-butoxycarbonyl)amino)cyclobutane-1-carboxylate (1.0 g, 4.4 mmol) in THF (20 mL) was added 3M lithium borohydride (9 mL, 9 mmol) at 0° C. Then the reaction mixture was heated and stirred at 60° C for 3 h. The reaction mixture was then transferred into dilute NaOH and the resulting mixture was extracted using ethyl acetate (3×50 mL). The combined organic layer was dried over anhydrous sodium sulfate and filtered. The filtrate was evaporated under reduced pressure and the crude product was purified using silica gel column chromatography (3% MeOH-DCM) to give tert-Butyl (trans-3-(hydroxymethyl)cyclobutyl)carbamate as a white solid (0.8 g, 91%).
Reactions
Tert-Butyl (trans-3-(hydroxymethyl)cyclobutyl)carbamate is an crucial organic compound that can be used to synthesize 3-Amino-cyclobutaneMethanol hydrochloride.
tert-Butyl (trans-3-(hydroxymethyl)cyclobutyl)carbamate Preparation Products And Raw materials
Raw materials
Preparation Products
tert-Butyl (trans-3-(hydroxymethyl)cyclobutyl)carbamate Suppliers
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