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2-Methyl-1-propanol

Isobutanol Chemical properties Uses Production method Hazards & Safety Information
2-Methyl-1-propanol
2-Methyl-1-propanol
CAS No.
78-83-1
Chemical Name:
2-Methyl-1-propanol
Synonyms
IBA;FEMA 2179;i-Butanol;sobutanol;ISOBUTANOL;iso-C4H9OH;BUTANOL-ISO;femanumber2179;ISOBUTANOL(SG);Isobutanol4x1L
CBNumber:
CB3158955
Molecular Formula:
C4H10O
Formula Weight:
74.12
MOL File:
78-83-1.mol

2-Methyl-1-propanol Properties

Melting point:
−108 °C(lit.)
Boiling point:
108 °C(lit.)
Density 
0.803 g/mL at 25 °C(lit.)
vapor density 
2.55 (vs air)
vapor pressure 
8 mm Hg ( 20 °C)
refractive index 
n20/D 1.396(lit.)
FEMA 
2179 | ISOBUTYL ALCOHOL
Flash point:
82 °F
storage temp. 
Flammables area
solubility 
water: miscible70g/L at 20°C
form 
Solid
color 
APHA: ≤10
Relative polarity
0.552
PH
7 (80g/l, H2O, 20℃)
explosive limit
1.5-12%(V)
Water Solubility 
95 g/L (20 ºC)
Merck 
14,5131
BRN 
1730878
Stability:
Stable. Flammable. Incompatible with strong oxidizing agents, aluminium.
CAS DataBase Reference
78-83-1(CAS DataBase Reference)
NIST Chemistry Reference
1-Propanol, 2-methyl-(78-83-1)
EPA Substance Registry System
1-Propanol, 2-methyl-(78-83-1)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xi
Risk Statements  10-37/38-41-67
Safety Statements  13-26-37/39-46-7/9
RIDADR  UN 1212 3/PG 3
WGK Germany  1
RTECS  NP9625000
TSCA  Yes
HazardClass  3
PackingGroup  III
HS Code  29051990
Hazardous Substances Data 78-83-1(Hazardous Substances Data)
Toxicity LD50 orally in rats: 2.46 g/kg (Smyth)
Symbol(GHS):
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H226 Flammable liquid and vapour Flammable liquids Category 3 Warning
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger P280, P305+P351+P338, P310
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
H336 May cause drowsiness or dizziness Specific target organ toxicity,single exposure; Narcotic effects Category 3 Warning P261, P271, P304+P340, P312,P403+P233, P405, P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P370+P378 In case of fire: Use … for extinction.
P405 Store locked up.
P403+P235 Store in a well-ventilated place. Keep cool.

2-Methyl-1-propanol price More Price(44)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 1.00984 Isobutanol for analysis EMSURE ACS,Reag. Ph Eur 78-83-1 1EA $85.5 2017-11-08 Buy
Sigma-Aldrich 1.00984 Isobutanol for analysis EMSURE ACS,Reag. Ph Eur 78-83-1 2EA $178 2017-11-08 Buy
TCI Chemical I0094 2-Methyl-1-propanol >99.0%(GC) 78-83-1 25mL $16 2017-12-01 Buy
TCI Chemical I0094 2-Methyl-1-propanol >99.0%(GC) 78-83-1 500mL $22 2017-12-01 Buy
Alfa Aesar 022908 Isobutanol, HPLC Grade, 99+% 78-83-1 *4x1L $152 2018-11-16 Buy

2-Methyl-1-propanol Chemical Properties,Uses,Production

Isobutanol

Isobutanol, also known as isopropyl alcohol, 2-methyl propanol is a colorless alcohol flammable liquid. Isobutanol is one of the main ingredients of fresh tea leaves, black tea and green tea to produce the wonderful aroma with the molecular weight of 74.12, boiling point of 107.66 ℃, relative density of 0.8016 (20/4 ℃), refractive index of 1.3959 and a flash point of 37 ℃. Isobutanol is fully dissolved in alcohol and ether, slightly soluble in water. Its vapor can form an explosive mixture with air; the explosion limit is 2.4% (volume). It can form addition compounds (CaCl2 • 3C4H10O) with calcium chloride. Isobutanol can be obtained by the distillation of the by-product of methanol and can also be derived from distillation of crude fusel oil. Using Industrial carbonyl cobalt as a catalyst, making propylene and carbon monoxide and hydrogen mixture react at 110~140 ° C, 2.0265 × 107~3.0397 × 107Pa to generate butyraldehyde and isobutyraldehyde, and then via catalytic hydrogenation, separation can obtain isobutanol. Isobutanol is used in the manufacture of petroleum additives, antioxidants, plasticizers, synthetic rubber, artificial musk, fruit oil and synthetic drugs and also used as solvents and chemical reagents.

Chemical properties

It is a kind of colorless transparent liquid with a special smell, soluble in water, and fully dissolved in ethanol and ether.

Uses

(1)  For analysis reagents, chromatography reagents, solvents and extraction agent.
(2)  As raw materials for the organic synthesis, and also act as a superior solvent.
(3)  Isobutanol is raw materials for organic synthesis. It mainly used in the synthesis of isobutyronitrile, an intermediate for diazinon.
(4)  As raw materials of organic synthesis, isobutanol is used in the manufacture of petroleum additives, antioxidants, 2, 6-butylated hydroxytoluene, isobutyl acetate (paint solvents), plasticizers, synthetic rubber, artificial musk, fruit oil and synthetic drugs. It can also be used to purify strontium, barium and lithium salts and other chemical reagents and used as a superior solvent.
(5)  Extraction solvent. Food flavors listed in GB 2760-96.

Production method

(1) In the presence of sodium amalgam or other catalysts, it is derived from the reduction of butyraldehyde;r it is derived from the distillation of the by-product obtained from the synthesis of methanol.
(2) 1. Carbonyl synthesis (by-product of butanol production from propylene) : using propylene and synthesis gas as raw material, going through  carbonyl synthesis in the system to get  n-butyl and isobutyl  aldehyde, after the catalyst, hydrogenating into alcohol, then undergoing dehydration and separation can obtain the product of   n-butyl and isobutyl  alcohol respectively.
2. Hydrogenation of isobutyraldehyde: isobutyraldehyde via the liquid hydrogenation reaction, obtained isobutanol in the catalytic nickel.
3. Recycle from isobutyl oil, a byproduct of synthetic methanol distillation: isobutanol is obtained by dehydration of methanol, salting out and then azeotropic distillation of isobutyl oil.
(3) The preparation method is using synthesis gas and propylene as raw materials, obtaining isobutyraldehyde during the carbonyl synthesis of 2-ethylhexyl alcohol, and then by hydrogenation to acquire isobutanol.

Hazards & Safety Information

Category: Flammable liquids
Toxic classification: Moderately hazardous
Acute toxicity: Oral-Rat LD50: 2460 mg/kg; Abdominal-Mouse LD50: 1801 mg/kg
Stimulation data: Eye-Rabbit 2 mg Severity
Explosives hazardous characteristics: To be explosive when mix with air.
Flammability hazard characteristics: Flammable in case of fire, high temperature, oxidant; stimulating the smoke when combustion.
Storage and transportation characteristics: Ventilation and low-temperature drying in treasury; oxidants and acids stored separately.
Extinguishing agent: Dry powder, dry sand, carbon dioxide, foam.
Occupational Standard: TWA 50 PPM.

Chemical Properties

colourless oily liquid

Uses

Isobutyl Alcohol is a reagent used in organic reactions. It is used in the synthesis of new fluorinating reagents. It is also used in the lipase-catalyzed production of biodiesel as an energy source.

Definition

ChEBI: An alkyl alcohol that is propan-1-ol substituted by a methyl group at position 2.

Uses

manufacture of esters for fruit flavoring essences; solvent in paint, varnish removers.

General Description

A clear colorless liquid with a sweet odor. Flash point 85 - 100°F. Less dense than water. Vapors heavier than air.

Air & Water Reactions

Highly flammable. Soluble in water.

Reactivity Profile

2-Methyl-1-propanol is an alcohol. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert them to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides. 2-Methyl-1-propanol is incompatible with strong oxidizers.

Health Hazard

Contact with eyes is extremely irritating and may cause burns. Breathing vapors will be irritating to the nose and throat. In high concentrations, may cause nausea, dizziness, headache, and stupor.

Fire Hazard

HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.

Purification Methods

Isobutanol is dried by refluxing with CaO and BaO for several hours, followed by treatment with calcium or aluminium amalgam, then fractional distilling it from sulfanilic or tartaric acids. More exhaustive purifications involve formation of phthalate or borate esters. Heating it with phthalic anhydride gives the acid phthalate which, after crystallisation to constant melting point (m 65o) from pet ether, is hydrolysed with aqueous 15% KOH. The alcohol is distilled off as the water azeotrope and dried (K2CO3, then anhydrous CuSO4), and finally magnesium turnings, followed by fractional distillation. [Hückel & Ackermann J Prakt Chem 136 15 1933.] The borate ester is formed by heating the dried alcohol for 6hours in an autoclave at 160-175o with a quarter of its weight of boric acid. After fractional distillation under vacuum, the ester is hydrolysed by heating for a short time with aqueous alkali and the alcohol is dried with CaO and distilled. [Michael et al. J Am Chem Soc 38 653 1916.] Alternatively dry the alcohol with K2CO3, CaSO4 or CaCl2, filter and fractionally distil it. For further drying, the redistilled alcohol can be refluxed with the appropriate alkyl phthalate or succinate as described under ethanol. [Beilstein 1 IV 1588.]

2-Methyl-1-propanol Preparation Products And Raw materials

Raw materials

Preparation Products


2-Methyl-1-propanol Suppliers

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