Butyrophenone
- CAS No.
- 495-40-9
- Chemical Name:
- Butyrophenone
- Synonyms
- 1-Phenylbutan-1-one;Butanophenone;1-PHENYL-1-BUTANONE;Propyl phenyl ketone;BUTYROPHENONE;Buterophenone;Buthrophenone;Butyrylbenzene;N-BUTYROPHENONE;N-BUTANOPHENONE
- CBNumber:
- CB3167698
- Molecular Formula:
- C10H12O
- Molecular Weight:
- 148.2
- MDL Number:
- MFCD00009397
- MOL File:
- 495-40-9.mol
- MSDS File:
- SDS
| Melting point | 11-13 °C(lit.) |
|---|---|
| Boiling point | 228-230 °C(lit.) |
| Density | 1.021 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | 192 °F |
| storage temp. | Store below +30°C. |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Liquid |
| Specific Gravity | 0.988 |
| color | Clear colorless to yellow |
| Odor | at 100.00 %. camphor cherry walnut hazelnut |
| Odor Type | camphoreous |
| Water Solubility | Insoluble in water. |
| BRN | 508305 |
| Stability | Stable. Combustible. Incompatible with strong oxidizing agents. |
| LogP | 2.770 |
| CAS DataBase Reference | 495-40-9(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 186I11WB5B |
| NIST Chemistry Reference | 1-Butanone, 1-phenyl-(495-40-9) |
| EPA Substance Registry System | 1-Butanone, 1-phenyl- (495-40-9) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H317-H318-H227 | |||||||||
| Precautionary statements | P210-P370+P378-P403+P235-P501-P280-P305+P351+P338-P305+P351+P338+P310-P333+P313-P210e-P280a-P370+P378a-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 41-43 | |||||||||
| Safety Statements | 26-36/37/39-24/25-23 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29143900 | |||||||||
| NFPA 704 |
|
Butyrophenone price More Price(23)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 124338 | Butyrophenone ≥99% | 495-40-9 | 25g | $59 | 2024-03-01 | Buy |
| Sigma-Aldrich | 124338 | Butyrophenone ≥99% | 495-40-9 | 100g | $217 | 2024-03-01 | Buy |
| TCI Chemical | B0769 | Butyrophenone >99.0%(GC) | 495-40-9 | 25mL | $28 | 2024-03-01 | Buy |
| TCI Chemical | B0769 | Butyrophenone >99.0%(GC) | 495-40-9 | 100mL | $87 | 2024-03-01 | Buy |
| Alfa Aesar | A11345 | Butyrophenone, 99% | 495-40-9 | 25g | $28.65 | 2024-03-01 | Buy |
Butyrophenone Chemical Properties,Uses,Production
Description
Butyrophenone is a chemical compound with the formula C10H12O. Butyrophenone has been used to study the relationship between the electrolyte counter-ion concentration and the critical micelle concentration for several surfactants. It has been used to generate PhCO+ ions by 70 eV electron ionization. Some of its derivatives (called commonly butyrophenones) are used to treat various psychiatric disorders such as schizophrenia, as well as acting as antiemetics. They can interfere with neurotransmitter functions, usually blocking dopamine receptors, and induce behavioral, endocrine, motor-kinetic effects. Examples of butyrophenones include: Haloperidol, the most widely used classical antipsychotic drug in this class; Benperidol, the most potent commonly used antipsychotic ( 200 times more potent than chlorpromazine).
References
1. https://en.wikipedia.org/wiki/Butyrophenone
2. http://www.rightdiagnosis.com/medical/butyrophenone.htm
3. http://www.sigmaaldrich.com/catalog/product/aldrich/124338?lang=en®ion=CA
Chemical Properties
colourless to yellow liquid
Uses
Intermediates of Liquid Crystals
Uses
Butyrophenone is used as intermediates of Liquid Crystals
Synthesis Reference(s)
The Journal of Organic Chemistry, 61, p. 376, 1996 DOI: 10.1021/JO951500R
Tetrahedron Letters, 30, p. 6357, 1989 DOI: 10.1016/S0040-4039(01)93893-6
Biochem/physiol Actions
Butyrophenones constitutes neuroleptic drugs and interacts with the opiate receptor by inhibiting the stereospecific binding of 3H-naloxone.
Butyrophenone Preparation Products And Raw materials
Raw materials
Preparation Products
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| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21695 | 55 |
| Shanghai Yingrui Biopharma Co., Ltd. | +86-21-33585366 - 03@ | sales03@shyrchem.com | CHINA | 738 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| QINGDAO HONG JIN CHEMCIAL CO.,LTD. | 532-83657313 | hjt@hong-jin.com | China | 228 | 58 |
| Jinan Shengqi pharmaceutical Co,Ltd | 86+18663751872 | christine@shengqipharm.com | CHINA | 491 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8823 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 | sales@amoychem.com | China | 6387 | 58 |
| Shanghai Longyu Biotechnology Co., Ltd. | +8615821988213 | info@longyupharma.com | China | 2531 | 58 |
View Lastest Price from Butyrophenone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-07-02 | Butyrophenone, Phenyl n-propyl ketone
495-40-9
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
 |
2020-12-22 | Butyrophenone
495-40-9
|
US $10.00 / KG | 1KG | 99.5% | 100 | Hebei Guanlang Biotechnology Co., Ltd. | |
 |
2019-07-31 | Butyrophenone
495-40-9
|
US $1.80-3.60 / KG | 1KG | 98% | 88kg | Career Henan Chemical Co |
-
- Butyrophenone, Phenyl n-propyl ketone
495-40-9
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- Butyrophenone
495-40-9
- US $10.00 / KG
- 99.5%
- Hebei Guanlang Biotechnology Co., Ltd.
-
- Butyrophenone
495-40-9
- US $1.80-3.60 / KG
- 98%
- Career Henan Chemical Co
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