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Dexpanthenol

Description References
Dexpanthenol
Dexpanthenol structure
CAS No.
81-13-0
Chemical Name:
Dexpanthenol
Synonyms
Cozyme;Ilopan;Pantol;Urupan;Proleus;Motilyn;Panadon;synapan;Bepantol;Intrapan
CBNumber:
CB3169304
Molecular Formula:
C9H19NO4
Formula Weight:
205.25
MOL File:
81-13-0.mol

Dexpanthenol Properties

Melting point:
64~69℃
alpha 
30.5 º (c=5, H2O on anh. sub)
Boiling point:
118-120 °C (2.7 mmHg)
Density 
1.20 g/mL at 20 °C(lit.)
refractive index 
1.495-1.502
Flash point:
118-120°C/0.02m
storage temp. 
−20°C
form 
Viscous Liquid or Semi Solid
color 
Clear colorless to slightly yellow
PH
pH (100g/l,25℃) : 8.5~10.5
optical activity
[α]20/D +30±1°, c = 5% in H2O
Water Solubility 
soluble
Sensitive 
Hygroscopic
Merck 
14,2947
BRN 
1724947
InChIKey
SNPLKNRPJHDVJA-ZETCQYMHSA-N
CAS DataBase Reference
81-13-0(CAS DataBase Reference)
NIST Chemistry Reference
Dexpanthenol(81-13-0)
EPA Substance Registry System
Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)- 3,3-dimethyl-, (2R)-(81-13-0)

SAFETY

Hazard Codes  Xn
Risk Statements  36/37/38-48-41-37/38-20/21/22
Safety Statements  23-24/25-45-36/37/39-26-22
WGK Germany  1
RTECS  ES4316000
3-10
TSCA  Yes
HS Code  29241990
Hazardous Substances Data 81-13-0(Hazardous Substances Data)

Dexpanthenol price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 76200 D-Panthenol ≥98.0% (NT) 81-13-0 25ml $43.8 2018-11-13 Buy
Sigma-Aldrich 1179504 Dexpanthenol Pharmaceutical Secondary Standard; Certified Reference Material 81-13-0 500mg $62.3 2018-11-13 Buy
TCI Chemical P0692 D-Panthenol >98.0%(T) 81-13-0 25g $22 2018-11-22 Buy
TCI Chemical P0692 D-Panthenol >98.0%(T) 81-13-0 500g $169 2018-11-22 Buy
Alfa Aesar A18499 D-Panthenol, 98+% 81-13-0 500g $162 2018-11-13 Buy

Dexpanthenol Chemical Properties,Uses,Production

Description

Dexpanthenol belongs to a derivative of pantothenic acid (vitamin B5). It can penetrate the skin and mucous membrane to be quickly oxidized to pantothenic acid. The later one is extremely hygroscopic and binds water effectively. Therefore, Dexpanthenol can be used as a moisturizer. It is added to pharmaceutical and cosmetic products to relieve itching and improve wound healing. In ointments, it can be used for the treatment of sunburns, mild burns, minor skin injuries and disorders. It is also immediately applied after major abdominal surgery to minimize the possibility of paralytic ileus. In addition, it can also be supplemented into the commercial shampoos and hair conditioners to lubricate the hair shaft and give the hair a shiny appearance. The exact mechanism of action of Dexpanthenol is still unclear, perhaps through its enhancing effect on acetylcholine.  

References

https://pubchem.ncbi.nlm.nih.gov/compound/Dexpanthenol#section=Top
https://www.drugs.com/pro/dexpanthenol.html
https://de.wikipedia.org/wiki/Dexpanthenol

Chemical Properties

clear colorless to slightly yellow viscous liquid

Uses

cholinergic

Uses

D-Panthenol is an analogue of pantothenic acid (P190300), a member of the B complex vitamins. D-Panthenol is the biologically active enantiomer of Panthenol.

Uses

immunosuppressant, mitoxantrone analogue less toxic on cardiac tissue antineoplastic

brand name

D-Panthenol 50 (BASF); Ilopan (Savage); Motilyn (Abbott).

Contact allergens

Pan(to)thenol is the alcohol corresponding to pantothenic acid, of the vitamin B5 group. It is used as a food additive, and in skin and hair products as a conditioning agent. Contact dermatitis and urticaria have been reported.

Safety Profile

Moderately toxic by intravenous route. A skin and eye irritant. When heated to decomposition it emits toxic fumes of NOx. See also AMIDES.

Veterinary Drugs and Treatments

Dexpanthenol has been suggested for use in intestinal atony or distension, postoperative retention of flatus and feces, prophylaxis and treatment of paralytic ileus after abdominal surgery or traumatic injuries, equine colic (not due to mechanical obstruction) and any other condition when there is an impairment of smooth muscle function. Controlled studies are lacking with regard to proving the efficacy of the drug for any of these indications.

Purification Methods

Purify D-panthenol by distillation in vacuo. It is a slightly hygroscopic viscous oil and is soluble in H2O and organic solvents. It is hydrolysed by alkali and strong acid. [Rabin J Am Pharm Assoc (Sci Ed) 37 502 1948, Bonati & Pitré Farmaco Ed Scient 14 43 1959, Beilstein 4 IV 1652.]

Dexpanthenol Preparation Products And Raw materials

Raw materials

Preparation Products


Dexpanthenol Suppliers

Global( 270)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 info@tnjchem.com China 1787 55
Zhonglan Industry Co., Ltd.
(86) 531-82956570
(86) 531-82956571 sales@zhonglanindustry.com CHINA 808 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23959 58
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3203 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21935 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20676 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32452 55
Hangzhou FandaChem Co.,Ltd.
0086 158 5814 5714 (Mobile; WhatsApp; Telegram)
+86-571-56059825 fandachem@gmail.com CHINA 2734 55
Nanjing Finetech Chemical Co., Ltd.
025-85710122 17714198479
025-85710122 sales@fine-chemtech.com CHINA 892 55
Tianjin Zhongxin Chemtech Co., Ltd.
022-89880739
022-66880086 sales@tjzxchem.com CHINA 575 58

View Lastest Price from Dexpanthenol manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-07-26 Dexpanthenol
81-13-0
US $15.00 / KG 1KG 99% 1000KG career henan chemical co

Dexpanthenol Spectrum


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