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Econazole nitrate

Description References
Econazole nitrate
Econazole nitrate structure
CAS No.
24169-02-6
Chemical Name:
Econazole nitrate
Synonyms
Amicel;Pargin;Gynoryl;Micogin;SQ 13050;Micofugal;NSC 243115;Gyno-Pevaril;Gyno-prevaryl;Econazole 
CBNumber:
CB3173103
Molecular Formula:
C18H16Cl3N3O4
Formula Weight:
444.7
MOL File:
24169-02-6.mol

Econazole nitrate Properties

Melting point:
162°C
storage temp. 
Refrigerator
solubility 
chloroform/methanol: soluble25mg/mL (choloroform:methanol (1:1))
form 
powder
color 
white to off-white
Water Solubility 
<0.1 g/100 mL at 19 ºC
Merck 
14,3502
InChIKey
DDXORDQKGIZAME-UHFFFAOYSA-N
CAS DataBase Reference
24169-02-6(CAS DataBase Reference)
EWG's Food Scores
2
FDA UNII
H438WYN10E
EPA Substance Registry System
Econazole mononitrate (24169-02-6)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319
Precautionary statements  P305+P351+P338-P280a-P301+P312a-P321-P332+P313-P501a
Hazard Codes  Xn,Xi
Risk Statements  22-36/38-36/37/38
Safety Statements  26-36-36/37
WGK Germany  3
RTECS  NI4450000
HS Code  29332900
Toxicity LD50 in mice, rats (mg/kg): 462.7, 667.7 orally (Thienpont)

Econazole nitrate price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich E4632 Econazole nitrate salt 24169-02-6 5g $57.2 2019-12-02 Buy
Sigma-Aldrich E4632 Econazole nitrate salt 24169-02-6 25g $247 2019-12-02 Buy
TCI Chemical E0957 Econazole Nitrate >98.0%(HPLC)(T) 24169-02-6 5g $48 2020-06-24 Buy
TCI Chemical E0957 Econazole Nitrate >98.0%(HPLC)(T) 24169-02-6 25g $173 2020-06-24 Buy
Alfa Aesar J63173 Econazole nitrate 24169-02-6 5g $54.2 2020-06-24 Buy

Econazole nitrate Chemical Properties,Uses,Production

Description

Econazole nitrate is the nitrate salt form of Econazole. It belongs to imidazole-class antifungal medication sold in various places around the world including US, Canada, Western Europe, and Asia. It is usually manufactured into cream form for sale. Econazole nitrate is mainly used for the treatment of skin infections including athlete's foot, tinea, pityriasis versicolor, ringworm, and jock itch caused by fungi such as Trichophyton rubrum, Trichophyton tonsurans and Microsporum audouini. As an imidazole-class drug, Econazole nitrate takes effects through inhibiting the biosynthesis of ergosterol, a key component of fungal cell membrane, thus disrupting the normal permeability of fungal membrane. This causes leakage of essential cellular contents of fungi, further killing them.

References

http://www.rxlist.com/econazole-nitrate-cream-drug/clinical-pharmacology.htm
https://en.wikipedia.org/wiki/Econazole
http://www.pdr.net/drug-summary/Econazole-Nitrate-econazole-nitrate-731

Chemical Properties

White to Off-White Solid

Uses

Antifungal;Ergosterol synthesis inhibition

Uses

Azole antifungal

Uses

Econazole nitrate is an antifungal agent of the imidazole type used in topical and vaginal preparations to prevent growth of dermatophytes, yeast, and mold.

brand name

Spectazole (Johnson & Johnson).

General Description

White crystalline powder.

Air & Water Reactions

Insoluble in water.

Fire Hazard

Flash point data for Econazole nitrate are not available; however, Econazole nitrate is probably combustible.

Econazole nitrate Preparation Products And Raw materials

Raw materials

Preparation Products


Econazole nitrate Suppliers

Global( 222)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Shanghai Bojing Chemical Co.,Ltd.
+86-21-37122233
+86-21-37127788 Candy@bj-chem.com CHINA 497 55
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 linda@hubeijusheng.com CHINA 28231 58
Haihang Industry Co.,Ltd
86-531-88032799
+86 531 8582 1093 export@haihangchem.com CHINA 10154 58
HENAN BON INDUSTRIAL CO.,LTD
0371-55170695
info@hnbon.com CHINA 20535 58
CONIER CHEM AND PHARMA LIMITED
86-18523575427
sales@conier.com CHINA 47486 58
career henan chemical co
0086-371-86658258
0086-371-86658258 factory@coreychem.com CHINA 29643 58
Shaanxi Dideu Medichem Co. Ltd
18192627656
+86-29-88380327 1012@dideu.com CHINA 3898 58
Amadis Chemical Company Limited
0086-571-89925085
0086-571-89925065 sales@amadischem.com China 132149 58
Shenzhen Sendi Biotechnology Co.Ltd. 0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3194 55
Mainchem Co., Ltd. +86-0592-6210733
+86-0592-6210733 sale@mainchem.com CHINA 32444 55

View Lastest Price from Econazole nitrate manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2020-05-12 Econazole Nitrate
24169-02-6
US $0.01-1.00 / KG 1KG 99% 50 tons Shaanxi Dideu Medichem Co. Ltd
2019-12-31 Econazole nitrate
24169-02-6
US $1.00 / g 1g 99% 10000KGS Career Henan Chemical Co

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