ChemicalBook >> CAS DataBase List >>17ALPHA-HYDROXYPREGNENOLONE
17ALPHA-HYDROXYPREGNENOLONE
- CAS No.
- 387-79-1
- Chemical Name:
- 17ALPHA-HYDROXYPREGNENOLONE
- Synonyms
- NSC 63853;17-OH PREG;17alpha-Hydroxy;17-OH Pregnenolone;Dronedarone HCl-d6;Hydroxypregnenolone;17a-Hydroxypregnolone;17A-HYDROXYPREGENOLONE;17-HYDROXYPREGNENOLONE;17α-Hydroxypregnenolone
- CBNumber:
- CB3175435
- Molecular Formula:
- C21H32O3
- Molecular Weight:
- 332.48
- MDL Number:
- MFCD00021129
- MOL File:
- 387-79-1.mol
Last updated:2023-05-18 11:31:19
| Melting point | 273℃ |
|---|---|
| Flash point | 9℃ |
| storage temp. | -20°C |
| solubility | Chloroform (Slightly), DMSO (Slightly, Heated, Sonicated) |
| form | Solid |
| Boiling point | 478.4±45.0 °C(Predicted) |
| Density | 1.15±0.1 g/cm3(Predicted) |
| pka | 13.02±0.70(Predicted) |
| color | White to Off-White |
| CAS DataBase Reference | 387-79-1(CAS DataBase Reference) |
| FDA UNII | 77ME40334S |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS02,GHS06,GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H225-H301+H311+H331-H370 |
| Precautionary statements | P210-P260-P280-P301+P310-P311 |
| Hazard Codes | F,T |
| Risk Statements | 11-23/24/25-39/23/24/25 |
| Safety Statements | 7-16-36/37-45 |
| RIDADR | UN1230 - class 3 - PG 2 - Methanol |
| WGK Germany | 3 |
| RTECS | TU5548000 |
17ALPHA-HYDROXYPREGNENOLONE price More Price(23)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | H5002 | 17α-Hydroxypregnenolone | 387-79-1 | 5g | $562 | 2024-03-01 | Buy |
| Sigma-Aldrich | H-105 | 17α-Hydroxypregnenolone solution 100?μg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant? | 387-79-1 | 1mL | $128 | 2024-03-01 | Buy |
| Sigma-Aldrich | S518034 | 3BETA,17ALPHA-DIHYDROXYPREGN-5-EN-20-ONE AldrichCPR | 387-79-1 | 250MG | $28.6 | 2022-05-15 | Buy |
| Sigma-Aldrich | R199400 | 3-BETA,17-ALPHA-DIHYDROXYPREGN-5-EN-20-ONE AldrichCPR | 387-79-1 | 1MG | $28.6 | 2022-05-15 | Buy |
| Cayman Chemical | 29181 | 17α-hydroxy Pregnenolone | 387-79-1 | 100mg | $44 | 2024-03-01 | Buy |
17ALPHA-HYDROXYPREGNENOLONE Chemical Properties,Uses,Production
Description
17α-hydroxy Pregnenolone is a metabolite of pregnenolone and a precursor in the biosynthesis of dehydroepiandrosterone (DHEA; ). It is formed from pregnenolone by cytochrome P450 (CYP) isoform CYP17A1 hydroxylase activity and then converted to dehydroepiandrosterone by CYP17A1-mediated 17,20-lyase activity. Plasma levels of 17α-hydroxy pregnenolone are elevated in patients with type II 3β-hydroxysteroid dehydrogenase deficiency, a form of congenital adrenal hyperplasia.
Uses
17α-hydroxypregnenolone has been used as a substrate for the enzyme 3β‐hydroxysteroid dehydrogenase (3β‐HSD) expressed in COS1 cells.
General Description
17α-hydroxypregnenolone is a derived from pregnenolone.
Biochem/physiol Actions
17α-hydroxypregnenolone acts as a precursor for cortisol and sex steroids.
17ALPHA-HYDROXYPREGNENOLONE Preparation Products And Raw materials
Raw materials
Androst-5-ene-17-carbonitrile, 3-(acetyloxy)-17-hydroxy-, (3β,17α)- (9CI)
Pregn-5-en-20-one, 3-(acetyloxy)-16-bromo-17-hydroxy-, (3β)- (9CI)
Pregn-5-en-20-one, 17-hydroperoxy-3-hydroxy-, (3β)- (9CI)
Pregn-5-en-20-one,16-bromo-3,17-dihydroxy-, (3b,16b)- (9CI)
3-beta,17-alpha-dihydroxypregn-5-en-20-one 3-acetate
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Preparation Products
17ALPHA-HYDROXYPREGNENOLONE Suppliers
Global( 90)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Mainchem Co., Ltd. | +86-0592-6210733 | sale@mainchem.com | China | 32360 | 55 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006608290; 18621169109 | market03@meryer.com | China | 40241 | 62 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| Shanghai Tauto Biotech Co., Ltd. | 021-51320588 | tauto@tautobiotech.com | China | 3989 | 66 |
| ChemStrong Scientific Co.,Ltd | 0755-66853366 13670046396 | sales@chem-strong.com | China | 17982 | 56 |
| Shanghai Macklin Biochemical Co.,Ltd. | 15221275939 15221275939 | shenlinxing@macklin.cn | China | 15878 | 55 |
387-79-1(17ALPHA-HYDROXYPREGNENOLONE)Related Search:
21-hydroxypregnenolone 3-acetate
17ALPHA-HYDROXYPREGNENOLONE-3,17-DIACETATE,17-HYDROXYPREGNENOLONE DIACETATE,17A-HYDROXYPREGNENOLONE-3,17-DIACETATE,17ALPHA-HYDROXYPREGNENOLONE-3,17-DIACETATE
Pregnenolone
16BETA-METHYL-17ALPHA-HYDROXYPREGNENOLONE,16BETA-METHYL-17ALPHA-HYDROXYPREGNENOLONE
17ALPHA-HYDROXYPREGNENOLONE 17-ACETATE,17ALPHA-HYDROXYPREGNENOLONE 17-ACETATE,17A-HYDROXYPREGNENOLONE-17-ACETATE
17-HYDROXYPREGNENOLONE 3-ACETATE,17ALPHA-HYDROXYPREGNENOLONE 3-ACETATE,17A-hydroxypregnenolone 3-acetate,17ALPHA-HYDROXYPREGNENOLONE 3-ACETATE
20-BETA-HYDROXYPREGNENOLONE
6-methyl-17alpha-hydroxypregnenolone diacetate,6-methyl-17alpha-hydroxypregnenolone diacetate
16-METHYLENE-17ALPHA-HYDROXYPREGNENOLONE 3-ACETATE
16-ALPHA-HYDROXYPREGNENOLONE,16-ALPHA-HYDROXYPREGNENOLONE-3-SULFATE,16A-hydroxypregnenolone
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17alpha-Hydroxy
(3b)-3,17-dihydroxy-Pregn-5-en-20-one
17a-Hydroxypregnolone
17ALPHA-LPHA-HYDROXYPREGNENOLONE
5-Pregnen-3b,17-dihydroxy-3-one
3β,17α-Dihydroxy-5-pregnen-20-one, 5-Pregnene-3β,17α-diol-20-one
17-OH PREG
17-OH Pregnenolone
3β,17-Dihydroxypregn-5-en-20-one
3β,17α-Dihydroxypregn-5-en-20-one
3-beta,17-dihydroxypregn-5-en-20-one
3-beta,17-alpha-dihydroxypregn-5-en-20-one
Hydroxypregnenolone
17ALPHA-LPHA-HYDROXYPREGNENOLONE 3H ASSAY ASSAY CHARACTERISTICS
17ALPHA-LPHA-HYDROXYPREGNENOLONE (1,2-3 H)
17ALPHA-LPHA-HYDROXYPREGNENOLONE 3H RIA KIT ASSAY CHARACTERISTICS
17ALPHA-LPHA-HYDROXYPREGNENOLONE CRYSTALLINE
17α-Hydroxypregnenolone,3β,17α-Dihydroxy-5-pregnen-20-one, 5-Pregnene-3β,17α-diol-20-one
NSC 63853
3β,17α-Dihydroxy-5-pregnen-20-one
5-Pregnene-3β,17α-diol-20-one
17α-Hydroxypregnenolone solution
17α-hydroxypregnenolone solution,100ppm
3B 17A-DIHYDROXYPREGN-5-EN-20-ONE
3BETA,17ALPHA-DIHYDROXY-DELTA5-PREGNEN-20-ONE
3BETA,17ALPHA-DIHYDROXY-5-PREGNEN-20-ONE
3-BETA,17-DIHYDROXY-5-PREGNEN-3-ONE
5-PREGNENE-3BETA,17ALPHA-DIOL-20-ONE
5-PREGNEN-3-BETA, 17-DIOL-20-ONE
5-PREGNEN-3BETA-17A-DIOL-20-ONE
5-PREGNEN-3BETA,17ALPHA-DIOL-20-ONE
17-dihydroxy-(3-beta)-pregn-5-en-20-on
3-beta,17-dihydroxy-pregn-5-en-20-on
HYDROXYPREGNENOLONE, 17A-
17A-HYDROXYPREGENOLONE
17A-HYDROXY PREGNENOLONE
17ALPHA-HYDROXYPREGNENOLONE
17-HYDROXYPREGNENOLONE
Pregn-5-en-20-one, 3,17-dihydroxy-, (3β)-
17alpha-Hydroxypregnenolone-20,21-13C2,16,16-d2
17α-Hydroxypregnenolone
3b,17-Dihydroxy-5-pregnen-20-one
17α-Hydroxypregnenolone (Solution)
"17A-HYDROXY PREGNENOLONE 13C2,D2"
Inhibitor,17a Hydroxypregnenolone,Endogenous Metabolite,17aHydroxypregnenolone,inhibit,17a-Hydroxypregnenolone
Dronedarone HCl-d6
5-PREGNEN-3β, 17-DIOL-20-ONE
387-79-1
Steroids