ChemicalBook
Chinese Japanese Germany Korea

Trimethylsilylacetylene

Silican-protected group Application
Trimethylsilylacetylene
Trimethylsilylacetylene structure
CAS No.
1066-54-2
Chemical Name:
Trimethylsilylacetylene
Synonyms
TMSA;TMS ACETYLENE;Trimethylsilacetylene;Timethylsilyacetylene;Trimethylethynylsilane;ETHINYLTRIMETHYLSILANE;ETHYNYLTRIMETHYLSILANE;(Trimethylsilyl)ethyne;1-Trimethylsilylethyne;Ethyne,-trimethylsilyl
CBNumber:
CB3175930
Molecular Formula:
C5H10Si
Formula Weight:
98.22
MOL File:
1066-54-2.mol

Trimethylsilylacetylene Properties

Melting point:
>0°C
Boiling point:
53 °C(lit.)
Density 
0.695 g/mL at 25 °C(lit.)
vapor pressure 
4.18 psi ( 20 °C)
refractive index 
n20/D 1.388(lit.)
Flash point:
<−30 °F
storage temp. 
Store below +30°C.
solubility 
Miscible with organic solvents.
form 
liquid
color 
colorless
Specific Gravity
0.695
Water Solubility 
reacts
Hydrolytic Sensitivity
4: no reaction with water under neutral conditions
BRN 
906752
InChIKey
CWMFRHBXRUITQE-UHFFFAOYSA-N
CAS DataBase Reference
1066-54-2(CAS DataBase Reference)
NIST Chemistry Reference
(Trimethylsilyl)acetylene(1066-54-2)
EPA Substance Registry System
Trimethylsilylacetylene (1066-54-2)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H315-H319
Precautionary statements  P210-P305+P351+P338-P370+P378-P403+P235-P240-P241-P280a-P303+P361+P353-P501a
Hazard Codes  F,Xi
Risk Statements  11-36/37/38
Safety Statements  16-26-36
RIDADR  UN 1993 3/PG 2
WGK Germany  -
Hazard Note  Flammable/Irritant
TSCA  T
HazardClass  3
PackingGroup  II
HS Code  29310095
NFPA 704
3
1 0

Trimethylsilylacetylene price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 218170 Ethynyltrimethylsilane 98% 1066-54-2 5g $57.2 2021-03-22 Buy
Sigma-Aldrich 8.14226 Trimethylsilylacetylene for synthesis 1066-54-2 5 mL $57.81 2021-03-22 Buy
Sigma-Aldrich 218170 Ethynyltrimethylsilane 98% 1066-54-2 1g $29.6 2021-03-22 Buy
TCI Chemical T1239 Trimethylsilylacetylene >98.0%(GC) 1066-54-2 5mL $34 2021-03-22 Buy
TCI Chemical T1239 Trimethylsilylacetylene >98.0%(GC) 1066-54-2 25mL $101 2021-03-22 Buy

Trimethylsilylacetylene Chemical Properties,Uses,Production

Silican-protected group

Trimethylsilylacetylene is a silican-protected group, also known as trimethylethynylsilane, trimethylethynyl silicon and ethynyltrimethylsilane. It is a colorless transparent liquid at room temperature. It could be used to synthesize parazole by the addition of 1,3-bipolar ring of acetylene diazide. It is also the substrate of nickel catalyzed reaction and benzonitrile coupling reaction.

Application

Chemical Properties

CLEAR COLORLESS LIQUID

Physical properties

bp 53 °C; d 0.695 g cm?3.

Uses

Trimethylsilylacetylene is a valuable reagent used in ethynylation by palladium(0)-catalyzed coupling/condensation with aryl and vinyl halides and triflates, or by nucleophilic attack of the corresponding acetylide on electrophilic centers; reacts with alkyl iodides, tin hydrides,6 and dichloroketene in a regioselective and stereoselective manner, participating in the following synthesis reactions: Ethynylations, Palladium(0)-Catalyzed Coupling Reactions,Reaction of Trimethylsilylacetylides with Electrophiles, Radical-Initiated and Transition Metal-Catalyzed Additions, Cycloaddition Reactions, Ethynylations, Cycloaddition Reactions, Further Transformations etc.

Uses

Ethynyltrimethylsilane was used in: ? microwave-assisted, one-pot, three-step Sonogashira cross-coupling-desilylation-cycloaddition reaction for the preparation of 1,4-disubstituted 1,2,3-triazoles synthesis of poly(ethynyltrimethylsilane) containing Pd (II) coordination sites pyrazole synthesis via 1,3-dipolar cycloaddition of diazo compounds to acetylenes

Purification Methods

Distil it through an efficient column. The IR has bands at max 2041 (CC) and 3289 (C-H) cm-1. [Kr.hnke & Goss Chem Ber 92 30 1959, Beilstein 4 IV 3937.]

Trimethylsilylacetylene Preparation Products And Raw materials

Raw materials

Preparation Products


Trimethylsilylacetylene Suppliers

Global( 386)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Springchem New Material Technology Co.,Limited
+8613917661608 +86-021-62885108
info@spring-chem.com China 2065 57
Capot Chemical Co.,Ltd.
+86(0)13336195806 +86-571-85586718
+86-571-85864795 sales@capotchem.com China 20010 60
Henan DaKen Chemical CO.,LTD.
+86-371-66670886
info@dakenchem.com China 21022 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22607 55
Hangzhou FandaChem Co.,Ltd.
008615858145714
+86-571-56059825 fandachem@gmail.com CHINA 8882 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070
product@chemlin.com.cn CHINA 3013 60
ATK CHEMICAL COMPANY LIMITED
+86 21 5161 9050/ 5187 7795
+86 21 5161 9052/ 5187 7796 ivan@atkchemical.com CHINA 26734 60
Zjartschem
+86-571-8723 8903 jocelynpan@zjarts.com
+86-571-87063838 jocelynpan@zjarts.com CHINA 997 58
Shanxi Naipu Import and Export Co.,Ltd
+8613734021967
kaia@neputrading.com CHINA 1010 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 29959 58

Related articles


View Lastest Price from Trimethylsilylacetylene manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-10-27 Trimethylsilylacetylene
1066-54-2
US $80.00 / KG/Tin 1KG 99% 10Tons Hebei Senko Biotechnology Co., Ltd.
2021-10-21 TMS-acetylene
1066-54-2
US $1.00-280.00 / KG 0.5KG >99% 20tons Anhui Rencheng Technology Co., Ltd
2021-09-27 Trimethylsilylacetylene
1066-54-2
US $10.00 / KG 1KG 99% 10 mt Hebei Guanlang Biotechnology Co., Ltd.

1066-54-2(Trimethylsilylacetylene)Related Search:


Copyright 2017 © ChemicalBook. All rights reserved