ChemicalBook >> CAS DataBase List >>Polyinosinic acid-polycytidylic acid
Polyinosinic acid-polycytidylic acid
- CAS No.
- 24939-03-5
- Chemical Name:
- Polyinosinic acid-polycytidylic acid
- Synonyms
- polyi:c;polyi-c;Poly-Na;poly(i+c);Poly I:Cr;nsc-120949;polycpolyi;poly(ri:rc);Polyinosinic;polyri:polyrc
- CBNumber:
- CB3181814
- Molecular Formula:
- C19H27N7O16P2
- Molecular Weight:
- 671.41
- MDL Number:
- MFCD00131957
- MOL File:
- 24939-03-5.mol
Last updated:2024-02-06 18:17:50
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
|---|---|
| solubility | Water (Slightly) |
| form | Solid |
| color | White to Off-White |
| Water Solubility | Soluble to 3 mg/ml in water |
| Stability | Hygroscopic |
| InChIKey | ACEVNMQDUCOKHT-WOQDZEJINA-N |
| SMILES | O[C@@H]1[C@@H]([C@@H](COP(O)(O)=O)O[C@H]1N1C=CC(N)=NC1=O)O.O[C@@H]1[C@@H]([C@@H](COP(O)(O)=O)O[C@H]1N1C=NC2C(NC=NC1=2)=O)O |&1:1,2,3,11,22,23,24,32,r| |
| EWG's Food Scores | 1 |
| FDA UNII |
POLYINOSINIC-POLYCYTIDYLIC ACID (LOW MW) (3R630IWW5I) POLYINOSINIC-POLYCYTIDYLIC ACID (HIGH MW) (O84C90HH2L) |
| NCI Drug Dictionary | poly IC |
| ATC code | L03AX07 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H402 |
| Precautionary statements | P280-P305+P351+P338 |
| WGK Germany | 3 |
| RTECS | TR0175000 |
Polyinosinic acid-polycytidylic acid price More Price(16)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Tocris | 4287 | Poly(I:C) | 24939-03-5 | 10 | $98 | 2021-12-16 | Buy |
| Tocris | 4287 | Poly(I:C) | 24939-03-5 | 50 | $410 | 2021-12-16 | Buy |
| TRC | P688075 | Poly(I:C)(~90%) | 24939-03-5 | 50mg | $65 | 2021-12-16 | Buy |
| TRC | P688075 | Poly(I:C)(~90%) | 24939-03-5 | 250mg | $85 | 2021-12-16 | Buy |
| ApexBio Technology | B5551 | Poly(I:C) | 24939-03-5 | 10mg | $97 | 2021-12-16 | Buy |
Polyinosinic acid-polycytidylic acid Chemical Properties,Uses,Production
Uses
Poly(I:C) is a toll-like receptor 3 dsRNA inflammatory stimulant.
Definition
ChEBI: A mismatched double-stranded RNA with one strand being a polymer of inosinic acid, the other a polymer of cytidylic acid.
Biological Activity
poly (i:c), a synthetic double-stranded rna (dsrna) analog, is an immunostimulant that acts as the most potent interferon (ifn) inducer. toll-like receptor- 3 (tlr3) agonist[1].mixtures that included the tlr7/8 agonists r848 or cl075, combined with the poly (i:c), yield 3-d mature dendritic cells [2].commonly used to stimulate immune system activation in vivo. also promotes maturation of hpsc-derived cardiomyocytes[3].[1]. li y g, siripanyaphinyo u, tumkosit u, et al. poly (i:c), an agonist of toll-like receptor-3, inhibits replication of the chikungunya virus in beas-2b cells. virology journal, 2012, 9(1): 114.[2]. spranger s, javorovic m, burdek m, et al. generation of th1-polarizing dendritic cells using the tlr7/8 agonist cl075. the journal of immunology, 2010, 185(1): 738-747.[3]. biermann m1, cai w2, lang d, et al. epigenetic priming of human pluripotent stem cell-derived cardiac progenitor cells accelerates cardiomyocyte maturation. stem cells, 2019, 37(7): 910-923.
Polyinosinic acid-polycytidylic acid Preparation Products And Raw materials
Raw materials
1of4
Preparation Products
Global( 229)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing Duly Biotech Co.,Ltd | +undefined18013301590 | melody@njduly.com | China | 2452 | 58 |
| Wuhu Nuowei chemistry Co., Ltd. | +86-0553-2911116-802 +undefined17756524438 | sales1@nuowei-chem.com | China | 1642 | 58 |
| Hangzhou Meiya Pharmaceutical Co Ltd | +86-021-33686691 +8618001850931 | sales@meiyapharm.com | China | 57 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12456 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15928 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| Nanjing Finetech Chemical Co., Ltd. | 025-85710122 17714198479 | sales@fine-chemtech.com | CHINA | 885 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8823 | 58 |
View Lastest Price from Polyinosinic acid-polycytidylic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-03-11 | Polyinosinic-polycytidylic acid sodium salt (PIC)
24939-03-5
|
US $0.00-0.00 / kg | 1kg | ≥90.0% | 10 tons | Hangzhou Meiya Pharmaceutical Co Ltd | |
 |
2023-09-08 | Polyinosinic-polycytidylic acid sodium salt
24939-03-5
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd | |
 |
2023-03-06 | Polyinosinic acid-polycytidylic acid
24939-03-5
|
US $10.50 / KG | 1KG | 99% | 10 ton | Hebei Guanlang Biotechnology Co,.LTD |
-
- Polyinosinic-polycytidylic acid sodium salt (PIC)
24939-03-5
- US $0.00-0.00 / kg
- ≥90.0%
- Hangzhou Meiya Pharmaceutical Co Ltd
-
- Polyinosinic-polycytidylic acid sodium salt
24939-03-5
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd
-
- Polyinosinic acid-polycytidylic acid
24939-03-5
- US $10.50 / KG
- 99%
- Hebei Guanlang Biotechnology Co,.LTD
24939-03-5(Polyinosinic acid-polycytidylic acid)Related Search:
POLY(I) POLY(C)
POLYINOSINIC ACID POLYCYTIDYLIC ACID
POLYINOSINIC POLYCYTIDYLIC ACID
polyinosinic:polycytidylic acid copolymer
POLYCYTIDYLIC-INOSINIC ACID
Polyinosinic-polytidylin Acid.
POLYINOSINIC ACID . POLYCYTIDYLIC ACID, LYOPHILIZED
POLYCYTIDYLIC-INOSINIC ACID POTASSIUM
Polyinosinic
Polyinosinic Polycytidylic
POLYINOSINIC-POLYCYTIDILICACIDKSALT
Poly inosine-cytidine
5’-inosinicacid,homopolymer,complexwith5’-cytidylicacidhomopolymer(1:
5’-Inosinicacid,homopolymer,complexwith5’-cytidylicacidhomopolymer(1:1)
polyi:c
polyi-c
polyri:polyrc
Polycytidysic acid (Poly C)
Polyinosinic acid-po
nsc-120949
poly(i).poly(c)complex
poly(i+c)
poly(ri).(rc)
poly(ri).poly(rc)
poly(ri:rc)
polycpolyi
polycytidylic-polyinosinicacid
Polyinosinic-cytidylic acid disodiuM salt
Poly(I:C) (~90%)
Polyinosinic acid: polycytidylic acid (poly I:C)
Polyinosinic acid-polycytidylic acid USP/EP/BP
Poly I:Cr
Polyadenosinic acid sodium salt，Poly A
Poly-Na
Glycine Impurity 24
Polyinosinic-polycytidylic acid sodium salt (PIC)
24939-03-5
C10H11N4O7PnC9H12N3O7PnC38H50
C10H13N4O8PC9H14N3O8P
C19H27N7O16P2
C10H13N4O8PxC9H14N3O8Px
Nucleosides, Nucleotides, Oligonucleotides
Synthetic Oligonucleotides and Related Reagents
Biochemicals and Reagents
BioChemical
Material