Colestipol hydrochloride
- CAS No.
- 37296-80-3
- Chemical Name:
- Colestipol hydrochloride
- Synonyms
- lestid;colestid;cholestabyl;COLESTIPOL HCL;COLESTIPOL HYDROCHLORIDE;Colestipol Hydrochloride (200 mg);Colestipol Hydrochloride (1146505);n'-(2-aminoethyl)-n-[2-(2-aminoethylamino)ethyl]ethane-1,2-diamine 2-(chloromethyl)oxirane hydrochloride;N-(2-AMINOETHYL)-N'-[2-[(2-AMINOETHYL)AMINO]ETHYL]-1,2-ETHANEDIAMINE POLYMER WITH (CHLOROMETHYL)OXIRANE HYDROCHLORIDE
- CBNumber:
- CB3182169
- Molecular Formula:
- C8H24ClN5
- Molecular Weight:
- 225.76266
- MDL Number:
- MFCD01770708
- MOL File:
- 37296-80-3.mol
- MSDS File:
- SDS
| storage temp. | Room Temperature, under inert atmosphere |
|---|---|
| form | Solid |
| color | Off-White to Pale Yellow |
| FDA UNII | X7D10K905G |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P305+P351+P338 |
| WGK Germany | 3 |
| HS Code | 3914006000 |
| Toxicity | LD50 in rats (mg/kg): >4000 i.p.; >1000 orally (Webster, Bollert) |
Colestipol hydrochloride price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 1146505 | Colestipol hydrochloride | 37296-80-3 | 200mg | $454 | 2024-03-01 | Buy |
| TRC | C640093 | Colestipol hydrochloride | 37296-80-3 | 2mg | $50 | 2021-12-16 | Buy |
| TRC | C640093 | Colestipol hydrochloride | 37296-80-3 | 20mg | $85 | 2021-12-16 | Buy |
Colestipol hydrochloride Chemical Properties,Uses,Production
Uses
Antihyperlipidemic.
Uses
Colestipol Hydrochloride was useful for studying pharmacokinetics with Teriflunomide (A771726).
Definition
ChEBI: The hydrochloride of colestipol, a highly cross-linked, high molecular weight copolymer of diethylenetriamine and epichlorohydrin (hydrochloride), with approximately 1 out of 5 amine nitrogens protonated. It is used for binding bile acids in the intestine, inhibiting their reabsorption.
brand name
Colestid (Pharmacia & Upjohn).
General Description
Colestipol (Colestid) is ahigh–molecular-weight, insoluble, granular copolymer oftetraethylenepentamine and epichlorohydrin. It functions asan anion-exchange, resin-sequestering agent in a manner similarto that of cholestyramine resin. Colestipol hydrochloridereduces cholesterol levels without affecting triglycerides andseems to be especially effective in the treatment of type IIhyperlipoproteinemias.
Drug interactions
Potentially hazardous interactions with other drugs
Anticoagulants: may enhance or reduce effects of
coumarins and phenindione.
Ciclosporin: no reports of an interaction; however,
ciclosporin levels should be carefully monitored if
colestipol and ciclosporin are prescribed concurrently,
as colestipol may interfere with ciclosporin
absorption.
Metabolism
Not applicable as colestipol is not systemically absorbed.
Colestipol hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 47465 | 58 |
| AFINE CHEMICALS LIMITED | 0571-85134551 | info@afinechem.com | CHINA | 15377 | 58 |
| LGM Pharma | 1-(800)-881-8210 | inquiries@lgmpharma.com | United States | 2127 | 70 |
| Sinopharm Chemical Reagent Co,Ltd. | 86-21-63210123 | sj_scrc@sinopharm.com | China | 9823 | 79 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 010-50973186 4009686088 | 3193328036@qq.com | China | 18352 | 68 |
| Wuhan FengyaoTonghui Chemical Products Co., Ltd. | 027-87466105 15377573527 | 2678564200@qq.com | China | 17997 | 58 |
| DC Chemicals | 021-58447131 13564518121 | sales@dcchemicals.com | China | 9414 | 58 |
| Hubei Enxing Biotechnology Co., Ltd | 16621771607 | exbio_tech@163.com | China | 8364 | 58 |
| Hubei Qingbei Yunyan Pharmaceutical Technology Co., Ltd | 18162595016 | 3287908757@qq.com | China | 9514 | 58 |