N-NITROSOMORPHOLINE
- CAS No.
- 59-89-2
- Chemical Name:
- N-NITROSOMORPHOLINE
- Synonyms
- NMOR;NSC 139;nci-c02164;N-Nitrosomorfolin;NITROSOMORPHOLINE;N-Nitrosomorpholin;4-Nitrosomorpholine;4-nitroso-morpholin;n-nitroso-morpholin;N-NITROSOMORPHOLINE
- CBNumber:
- CB3185221
- Molecular Formula:
- C4H8N2O2
- Molecular Weight:
- 116.12
- MDL Number:
- MFCD00039710
- MOL File:
- 59-89-2.mol
| Melting point | 29°C |
|---|---|
| Boiling point | 225℃ |
| Density | 1.2829 (rough estimate) |
| refractive index | 1.4880 (estimate) |
| Flash point | 29 °C |
| storage temp. | 2-8°C |
| Water Solubility | Completely soluble in water |
| solubility | DMSO : 100 mg/mL (861.18 mM) |
| pka | -5.72±0.20(Predicted) |
| color | White or Colorless to Yellow |
| Merck | 14,6640 |
| Stability | Stable, but light-sensitive. Combustible. Incompatible with strong oxidizing agents. Refrigerate, store in the dark. |
| EWG's Food Scores | 1-3 |
| FDA UNII | 3L25FO7FN7 |
| Proposition 65 List | n-Nitrosomorpholine |
| IARC | 2B (Vol. 17, Sup 7) 1987 |
| EPA Substance Registry System | N-Nitrosomorpholine (59-89-2) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS06,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H351 | |||||||||
| Precautionary statements | P201-P301+P310+P330 | |||||||||
| Hazard Codes | Xn,T,F | |||||||||
| Risk Statements | 22-40-39/23/24/25-23/24/25-11 | |||||||||
| Safety Statements | 36/37-45-16-7 | |||||||||
| RIDADR | UN 2810 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | QE7525000 | |||||||||
| HS Code | 2934.99.9001 | |||||||||
| HazardClass | 6.1(b) | |||||||||
| PackingGroup | III | |||||||||
| Toxicity | LD50 orally in rats: 282 mg/kg (Druckrey) | |||||||||
| NFPA 704 |
|
N-NITROSOMORPHOLINE price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | N7382 | Nitrosomorpholine | 59-89-2 | 1ml | $158 | 2024-03-01 | Buy |
| Sigma-Aldrich | N7382 | Nitrosomorpholine | 59-89-2 | 5ml | $322.2 | 2024-03-01 | Buy |
| TCI Chemical | N0466 | N-Nitrosomorpholine >99.0%(GC) | 59-89-2 | 5g | $253 | 2024-03-01 | Buy |
| TCI Chemical | N0466 | N-Nitrosomorpholine >99.0%(GC) | 59-89-2 | 25g | $748 | 2024-03-01 | Buy |
| Sigma-Aldrich | Y0000822 | Molsidomine impurity B European Pharmacopoeia (EP) Reference Standard | 59-89-2 | y0000822 | $150 | 2024-03-01 | Buy |
N-NITROSOMORPHOLINE Chemical Properties,Uses,Production
Chemical Properties
yellow crystals or gold liquid
Uses
N-Nitrosomorpholine, a frequently used genotoxic model carcinogen. Toxicogenomic analysis of N-Nitrosomorpholine induced changes in rat liver.
Uses
Solvent for polyacrylonitrile; present during rubber manufacturing
Definition
ChEBI: A nitrosamine that is morpholine in which the hydrogen attached to the nitrogen is replaced by a nitroso group. A carcinogen and mutagen, it is found in snuff tobacco.
Synthesis Reference(s)
Synthetic Communications, 22, p. 2607, 1992 DOI: 10.1080/00397919208021659
General Description
Yellow crystals. Golden liquid with many crystals at 68°F.
Air & Water Reactions
Water soluble.
Reactivity Profile
N-NITROSOMORPHOLINE is incompatible with strong oxidizing agents .
Health Hazard
ACUTE/CHRONIC HAZARDS: When heated to decomposition N-NITROSOMORPHOLINE emits toxic fumes of nitrogen oxides.
Fire Hazard
Flash point data for N-NITROSOMORPHOLINE are not available; however, N-NITROSOMORPHOLINE is probably combustible.
Biochem/physiol Actions
Tumor initiator in rodent liver, trachea, nasal cavity, esophagus, kidney, lung, and thyroid.
Safety Profile
Confirmed carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Poison by ingestion, intraperitoneal, subcutaneous, and intravenous routes. Moderately toxic by inhalation. Human mutation data reported. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx. See also N-NITROSO COMPOUNDS.
Carcinogenicity
N-Nitrosomorpholine is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.
N-NITROSOMORPHOLINE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52867 | 58 |
| sgtlifesciences pvt ltd | +8617013299288 | dj@sgtlifesciences.com | China | 12382 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 49999 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| ShenZhen H&D Pharmaceutical Technology Co., LTD | +8613627253706 | sale@hdimpurity.com | China | 1504 | 58 |
| Shaanxi Didu New Materials Co. Ltd | +86-89586680 +86-13289823923 | 1026@dideu.com | China | 9116 | 58 |
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