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Succinylsulfathiazole

CAS No.
116-43-8
Chemical Name:
Succinylsulfathiazole
Synonyms
SST;rolsul;THIACYL;kaoxidin;KAOXIDINE;colistatin;sulfadigesin;SULFENTERONE;SST-PB3M-CPX;SST-PFB3-VME
CBNumber:
CB3187922
Molecular Formula:
C13H13N3O5S2
Molecular Weight:
355.39
MDL Number:
MFCD00022437
MOL File:
116-43-8.mol
MSDS File:
SDS
Last updated:2024-04-08 17:36:13

Succinylsulfathiazole Properties

Melting point 193.5°C
Density 1.4807 (rough estimate)
refractive index 1.6390 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility 1 M NaOH: soluble50mg/mL
pka pKa 4.5 (Uncertain)
form powder
color white to off-white
Water Solubility 0.49g/L(38 ºC)
λmax 282nm(H2O (pH 3.3 - 5))(lit.)
Merck 14,8877
BRN 349989
CAS DataBase Reference 116-43-8(CAS DataBase Reference)
FDA UNII RSS8647O4S
ATC code A07AB04
EPA Substance Registry System Butanoic acid, 4-oxo-4-[[4-[(2-thiazolylamino)sulfonyl]phenyl]amino]- (116-43-8)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H317
Precautionary statements  P280
Hazard Codes  Xn
Risk Statements  42/43
Safety Statements  22-36/37-45
RIDADR  3249
WGK Germany  3
RTECS  WM4767000
HazardClass  6.1(b)
PackingGroup  III
HS Code  29350090

Succinylsulfathiazole price More Price(18)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S364843 N1-(2-THIAZOLYL)-N4-SUCCINOYLSULFANILAMIDE Aldrich 116-43-8 250mg $110 2024-03-01 Buy
TCI Chemical S0991 Succinylsulfathiazole >97.0%(HPLC) 116-43-8 25g $50 2021-12-16 Buy
Usbiological 359043 Sst 116-43-8 48Tests $588 2021-12-16 Buy
Usbiological 384506 SST 116-43-8 96Tests $729 2021-12-16 Buy
Usbiological 384508 SST 116-43-8 96Tests $729 2021-12-16 Buy
Product number Packaging Price Buy
S364843 250mg $110 Buy
S0991 25g $50 Buy
359043 48Tests $588 Buy
384506 96Tests $729 Buy
384508 96Tests $729 Buy

Succinylsulfathiazole Chemical Properties,Uses,Production

Originator

Sulfasuxidine,MSD,US,1942

Uses

Succinylsulfathiazole is a sulfonamide antibiotic that was shown to inhibit bacteria that are responsible for folate production. Succinylsulfathiazole was used in various folate deficiency studies to block the synthesis of folic acid.

Uses

Succinylsulfathiazole is antibacterial

Definition

ChEBI: N-succinylsulfathiazole is a member of 1,3-thiazoles. It is functionally related to a sulfathiazole.

Manufacturing Process

3.92 g of succinic anhydride was added to a boiling suspension of 10 g of 2- sulfanilamidothiazole in 100 cc of alcohol. The mixture was then refluxed for five minutes after the addition was complete at which time all of the solids were in solution. The solution was then cooled and diluted with an equal volume of water. The white solid precipitate which formed was filtered and recrystallized from dilute alcohol, yielding 2-N4-succinylsulfanilamidothiazole, melting at 184°C to 186°C.

Therapeutic Function

Antibacterial (intestinal)

Succinylsulfathiazole Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 188)Suppliers
Supplier Tel Email Country ProdList Advantage
airuikechemical co., ltd.
+undefined86-15315557071 sales05@airuikechemical.com China 994 58
Hangzhou FandaChem Co.,Ltd.
008657128800458; +8615858145714 fandachem@gmail.com China 9341 55
SHANDONG ZHI SHANG CHEMICAL CO.LTD
+86 18953170293 sales@sdzschem.com China 2931 58
Xiamen AmoyChem Co., Ltd
+86-592-6051114 +8618959220845 sales@amoychem.com China 6387 58
Shandong chuangyingchemical Co., Ltd.
18853181302 sale@chuangyingchem.com CHINA 5909 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49391 58
SIMAGCHEM CORP
+86-13806087780 sale@simagchem.com China 17367 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6313 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250 1026@dideu.com China 28812 58

View Lastest Price from Succinylsulfathiazole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Succinylsulfathiazole (SST) pictures 2024-04-08 Succinylsulfathiazole (SST)
116-43-8
US $0.00-0.00 / Kg 1Kg 99.9% 200tons airuikechemical co., ltd.
Succinylsulfathiazole pictures 2023-05-25 Succinylsulfathiazole
116-43-8
US $0.00 / KG 0.1KG 98% 250KG Jiangsu Nata Opto-electronic Material Co.,Ltd.
Succinylsulfathiazole USP/EP/BP pictures 2021-07-13 Succinylsulfathiazole USP/EP/BP
116-43-8
US $1.10 / g 1g 99.9% 100 Tons Min Dideu Industries Group Limited
colistatin cremosuxidine kaoxidin KAOXIDINE sulfasuccidin sulfasuccidine sulfasuccinil sulfasuccithiazole 4-(Succinylamino)-N-(2-thiazolyl)benzenesulfonamide N4-Succinyl-N-(2-thiazolyl)sulfanilamide Succinylsulfathiazole Hydrate Butanoic acid, 4-oxo-4-[[4-[(2-thiazolylamino)sulfonyl]phenyl]amino]- 2-(n(4)-succinylsulfanilamido)thiazole 2-(N-SUCCINYLSULFANILAMIDO)THIAZOLE 4’-(2-thiazolylsulfamoyl)-succinanilicaci 4-oxo-4-((4-((2-thiazolylamino)sulfonyl)phenyl)amino)-butanoicaci succinylsulphathiazole sulfadigesin Sulfadigestin 4'-(2-THIAZOLYLSULFAMOYL)-SUCCINANILIC ACID THIACYL SUCCINYLSULFATHIAZOLE SULFENTERONE SULFASUXIDINE SST rolsul p-2-thiazolylsulfamoylsuccinanilic acid 4-(Succinylamino)-N-(2-thiazolyl)benzenesulfonamide N4-Succinyl-N-(2-thiazolyl)sulfanilamide 4-oxo-4-((4-(N-(thiazol-2-yl)sulfaMoyl)phenyl)aMino)butanoic acid N-succinylsulfathiazole N1-(2-THIAZOLYL)-N4-SUCCINOYLSULFANILAMIDE SST-PB3M-CPX SST-PFB3-VME APP-PS7-PCIE Succinylsulfathiazole (SST) Succinylsulfathiazole USP/EP/BP 116-43-8 C13H13N3O5S2 C13H13N3O5S2xH2O Antibiotics A to Z Antibiotics N-S Antibiotics BioChemical SULFASUXIDINE Antibacterial Antibiotics Antibiotics A to Antibiotics N-SAntibiotics Chemical Structure Class Inhibits an EnzymeAntibiotics Interferes with DNA SynthesisSpectrum of Activity L - ZAntibiotics Mechanism of Action Sulfonamides Antibiotics for Research and Experimental Use Biochemistry Sulfonamides (Antibiotics for Research and Experimental Use)