5-Fluoro-2-hydroxypyridine
- CAS No.
- 51173-05-8
- Chemical Name:
- 5-Fluoro-2-hydroxypyridine
- Synonyms
- 5-Fluoropyridin-2-ol;5-Fluoro-2-pyridinol;uoro-2-hydroxypyridine;5-fluoro-1H-pyridin-2-one;5-Fluoropyridin-2(1H)-one;3-Fluoro-6-hydroxypyridine;5-FLUORO-2-HYDROXYPYRIDINE;2-HYDROXY-5-FLUOROPYRIDINE;2(1H)-Pyridinone, 5-fluoro-;5- fluoro-2-hydroxyl pyridine
- CBNumber:
- CB3203611
- Molecular Formula:
- C5H4FNO
- Molecular Weight:
- 113.09
- MDL Number:
- MFCD03092918
- MOL File:
- 51173-05-8.mol
| Melting point | 150-155°C |
|---|---|
| Boiling point | 251.7±40.0 °C(Predicted) |
| Density | 1.26±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 10.09±0.10(Predicted) |
| form | Crystalline Powder |
| color | White to off-white |
| InChIKey | KLULSYPVWLJZAO-UHFFFAOYSA-N |
| CAS DataBase Reference | 51173-05-8(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|---|---|
| Signal word | Danger |
| Hazard statements | H302-H315-H318-H335 |
| Precautionary statements | P280-P301+P312+P330-P302+P352-P305+P351+P338+P310 |
| Hazard Codes | Xn |
| Risk Statements | 22-37/38-41 |
| Safety Statements | 26-39 |
| WGK Germany | 3 |
| HazardClass | IRRITANT |
| HS Code | 29333999 |
5-Fluoro-2-hydroxypyridine price More Price(32)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 753181 | 5-Fluoro-2-hydroxypyridine 97% | 51173-05-8 | 1g | $46.5 | 2023-06-20 | Buy |
| TRC | F597988 | 5-Fluoro-2-hydroxypyridine | 51173-05-8 | 50mg | $60 | 2021-12-16 | Buy |
| Matrix Scientific | 035690 | 5-Fluoro-2-hydroxypyridine 95+% | 51173-05-8 | 5g | $59 | 2021-12-16 | Buy |
| BroadPharm | BP-11523 | 5-fluoropyridin-2-olhydrobromide | 51173-05-8 | 5G | $185 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 35270 | 5-Fluoro-2-hydroxypyridine 98% | 51173-05-8 | 10g | $445 | 2021-12-16 | Buy |
5-Fluoro-2-hydroxypyridine Chemical Properties,Uses,Production
Uses
5-Fluoro-2-hydroxypyridine is a halogenated compound used in the synthesis of 5-Fluoro-2-hydroxy-3-nitropyridine and 5-halogenated pyrimidine compounds.
Synthesis
5-Fluoro-2-hydroxypyridine is synthesised using 5-fluoro-2-methoxypyridine as a raw material by chemical reaction. The specific synthesis steps are as follows:
A total of 4.6 L of toluene solution containing 3-80 was placed in several sealed tubes and treated with 900 ml of 35percent HCl at 145° C. for 2 hr. LC/MS showed no starting material, only 4. The toluene solution was decanted and discarded. The aqueous phase was washed with EtOAc and concentrated down to remove volatiles to afford a brown solid containing the desired fluoro-hydroxypyridine 4-80. [1488] A total of 244 g of this solid was collected and taken to next step as is (it was not completely dry). [1489] Note: We have subsequently run this by decanting the toluene layer first prior to heating to reduce volumes. Same reaction was carried out using HBr (48percent in H2O) at 100° C. for 6 h with similar result to the literature procedure 49percent yield. [1490] Ref: J. Heterocyclic Chem., 10, 779, 1973 (for above Reactions, Including Analytical Data).
5-Fluoro-2-hydroxypyridine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12456 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 7845 | 58 |
| Ouhuang Engineering Materials (Hubei) Co., Ltd | +8617702722807 | admin@hbouhuang.com | China | 2259 | 58 |
| Dongfan Chem. Co., Ltd. | 021-34500607 13391355195 | sales@dfanchem.com | CHINA | 61 | 55 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10248 | 58 |
| Accela ChemBio Inc. | (+1)-858-699-3322 | info@accelachem.com | United States | 19965 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8823 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10828 | 58 |
View Lastest Price from 5-Fluoro-2-hydroxypyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-25 | 5-Fluoro-2-hydroxypyridine
51173-05-8
|
US $50.00 / kg | 1kg | 99.10% | 50000kg | Ouhuang Engineering Materials (Hubei) Co., Ltd | |
 |
2024-04-08 | 5-Fluoro-2-hydroxypyridine
51173-05-8
|
US $5.00-0.10 / KG | 1KG | 98% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2023-08-08 | 5-Fluoro-2-hydroxypyridine
51173-05-8
|
US $0.00 / kg | 1kg | 99% | 1000tons | Hebei Mojin Biotechnology Co., Ltd |
-
- 5-Fluoro-2-hydroxypyridine
51173-05-8
- US $50.00 / kg
- 99.10%
- Ouhuang Engineering Materials (Hubei) Co., Ltd
-
- 5-Fluoro-2-hydroxypyridine
51173-05-8
- US $5.00-0.10 / KG
- 98%
- Henan Fengda Chemical Co., Ltd
-
- 5-Fluoro-2-hydroxypyridine
51173-05-8
- US $0.00 / kg
- 99%
- Hebei Mojin Biotechnology Co., Ltd
51173-05-8(5-Fluoro-2-hydroxypyridine)Related Search:
1of4