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Olivetol

CAS No.
500-66-3
Chemical Name:
Olivetol
Synonyms
1,3-Benzenediol, 5-pentyl-;5-PENTYLRESORCINOL;3,5-dihydroxyamylbenzene;Olivetol Powder;5-pentylbenzene-1,3-diol;CL213;ivetoL;Olidol;OLIVETOL;Oilvetol
CBNumber:
CB3204779
Molecular Formula:
C11H16O2
Molecular Weight:
180.24
MDL Number:
MFCD00002293
MOL File:
500-66-3.mol
MSDS File:
SDS
Last updated:2024-04-12 23:00:59

Olivetol Properties

Melting point 46-48 °C(lit.)
Boiling point 164 °C
Density 1.068±0.06 g/cm3(Predicted)
Flash point >230 °F
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
pka 9.59±0.10(Predicted)
color Colourless to Beige
Stability Light Sensitive
InChI InChI=1S/C11H16O2/c1-2-3-4-5-9-6-10(12)8-11(13)7-9/h6-8,12-13H,2-5H2,1H3
InChIKey IRMPFYJSHJGOPE-UHFFFAOYSA-N
SMILES C1(O)=CC(CCCCC)=CC(O)=C1
CAS DataBase Reference 500-66-3(CAS DataBase Reference)
FDA UNII 65OP0NEZ1P
NIST Chemistry Reference 1,3-Benzenediol, 5-pentyl-(500-66-3)
EPA Substance Registry System Olivetol (500-66-3)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS05,GHS07,GHS09
Signal word  Danger
Hazard statements  H302-H315-H318-H400
Precautionary statements  P273-P280-P301+P312+P330-P302+P352-P305+P351+P338+P310
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36/39
WGK Germany  3
RTECS  VH2880000
HS Code  2907290090

Olivetol price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 152633 Olivetol 95% 500-66-3 1g $63.8 2024-03-01 Buy
TRC O533000 Olivetol 500-66-3 5g $90 2021-12-16 Buy
TRC O533000 Olivetol 500-66-3 25g $250 2021-12-16 Buy
Matrix Scientific 084690 5-Pentylbenzene-1,3-diol 97% 500-66-3 25g $468 2021-12-16 Buy
Medical Isotopes, Inc. 60838 Olivetol 500-66-3 2.5g $595 2021-12-16 Buy
Product number Packaging Price Buy
152633 1g $63.8 Buy
O533000 5g $90 Buy
O533000 25g $250 Buy
084690 25g $468 Buy
60838 2.5g $595 Buy

Olivetol Chemical Properties,Uses,Production

Chemical Properties

Olivetol is an off-white crystals or olive to light purple waxy solid. Forms monohydrate (melting point: 102-106°F). Olivetol is a member of the class of resorcinols that is resorcinol in which the hydrogen at position 5 is replaced by a pentyl group. It has a role as a lichen metabolite.

Physical properties

light purple to brown crystalline mass.

Application

Olivetol is a precursor in various syntheses of tetrahydrocannabinol.

Uses

Olivetol was used as a template molecule in the synthesis of molecularly imprinted polymer (MIP). It was also used as an inhibitor of (S)-mephenytoin 4'-hydroxylase activity of recombinant CYP2C19.

Definition

ChEBI: Olivetol is a member of the class of resorcinols that is resorcinol in which the hydrogen at position 5 is replaced by a pentyl group. It has a role as a lichen metabolite.

Preparation

olivetol can also be formed through hydrolysis of intermediate polyketide CoAs or spontaneous cyclization.
synthesis of Olivetol

Synthesis Reference(s)

The Journal of Organic Chemistry, 42, p. 3456, 1977 DOI: 10.1021/jo00441a036

General Description

Olivetol appears as off-white crystals or olive to light purple waxy solid. Forms monohydrate (melting point: 102-106°F). (NTP, 1992)

Air & Water Reactions

Sensitive to air. Insoluble in water.

Reactivity Profile

Olivetol is incompatible with acid chlorides, acid anhydrides and oxidizing agents.

Fire Hazard

Olivetol is probably combustible.

Biological Activity

Olivetol (5-Pentylresorcinol, 5-n-Amylresorcinol) is a naturally occurring organic compound being a precursor in various syntheses of tetrahydrocannabinol. It acts as a competitive inhibitor of the cannabinoid receptors CB1 and CB2.

Safety

Olivetol is still a very new product. It has not been researched nearly enough to prove it's safe to use. So far, no one has reported any adverse side effects as far as we know. Until more information is available, carefully control your THC intake instead of relying on an untested gelcap.

Mode of action

When you look at olivetol's molecular structure, it'll look very familiar. It's as if someone took a THC molecule and sliced it in two. Olivetol, like THC, works by binding with the CB1 receptors that exist all over your body and brain. But, olivetol is thought to be smaller and stickier than THC, so that helps it reduce a raging high in two ways. First, it slips into any open receptors before THC can get there to block them—so you won't get any higher. Second, it bumps into THC molecules that are already lodged in a CB1 receptor to knock them loose and take their place. That's how it brings you down.
According to numerous personal accounts, olivetol works, but we don't know exactly how it does so. More research and investigation is needed, but in theory it's very similar to how Narcan acts to reverse opiate overdoses.

22976-40-5
500-66-3
Synthesis of Olivetol from Olivetol Dimethyl Ether
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Related Qustion

  • Q:Can Olivetol treat obesity?
  • A:Olivetol was able to inhibit the storage of excess fat in the liver caused by obesity (steatohepatitis) by lowering the levels....
  • Nov 20,2023

View Lastest Price from Olivetol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5-pentylbenzene-1,3-diol pictures 2024-04-23 5-pentylbenzene-1,3-diol
500-66-3
US $0.00-0.00 / kg 0.10000000149011612kg ≥98.5% 20tons Chongqing Zhihe Biopharmaceutical Co., Ltd.
Olivetol pictures 2024-04-23 Olivetol
500-66-3
US $0.00 / Kg/Bag 1KG 99% 50mt Jinan Finer Chemical Co., Ltd
Olivetol pictures 2024-04-23 Olivetol
500-66-3
US $5.00 / g 1g 99% 300tons Hebei Dangtong Import and export Co LTD
  • Olivetol pictures
  • Olivetol
    500-66-3
  • US $0.00 / Kg/Bag
  • 99%
  • Jinan Finer Chemical Co., Ltd
  • Olivetol pictures
  • Olivetol
    500-66-3
  • US $5.00 / g
  • 99%
  • Hebei Dangtong Import and export Co LTD
5-PENTYL 1,3-BENZENEDIOL 5-N-PENTYLRESORCINOL 5-AMYL RESORCINOL AURORA KA-7378 OLIVETOL 5-n-amylresorcinol 5-pentyl-3-benzenediol 5-pentyl-resorcino 1,3-Dihydroxy-5-pentylbenzene, 3,5-Dihydroxyamylbenzene, 5-Pentylresorcinol Olivetol,98% n-Amylresolcinol Oilvetol Pentyl-3,5-dihydroxybenzene Olivetol(3,5-Dihydroxyamylbenzene) 1,3-dihydroxy-5-pentylbenzene Resorcinol, 5-pentyl. Olivetol, GC 95% 5-Pentylresorcinol( Olivetol) 1,3-dyhydroxy-5-n-aMylnenzene 3,5-dyhydroxy aMylbenzene 3,5-DIHYDROXY-1-AMYL BENZENE Olivetol 95% 3,5-hydroxypentylbenzene Olivetol(3,5-hydroxypentylbenzene) Olivetol 500-66-3 3,5-hydroxypentylbenzene 3,5-hydroxypentylbenzene 500-66-3 Olivetol 3,5-Dihydroxypentylbenzene CL213 ivetoL 3,5-dihydroxyamylbenzene,Oilvetol 1-Pentyl-3,5-dihydroxybenzene High Purity 99% Olivetol/5-Pentylresorcinol Powder 500-66-3 Olivetol Synonyms:3,5-hydroxypentyl benzene) Olidol 2-Distearoyl-sn-glycero-3-PC DISTEAROYL 5-PENTYLRESORCINOL 3,5-dihydroxyamylbenzene 5-pentylbenzene-1,3-diol 1,3-Benzenediol, 5-pentyl- Olivetol Powder Olivetol,95% Pyridoxine hydrochloride 58-56-0 Olivetol (6CI) Olivetol, 95% (Custom work) 500-66-3 50-06-3 500-86-3 500-6-3 475-66-3 CH3CH24C6H313OH2 CH3CH24C6H3OH2 Oxygen Compounds Polyols Organic Building Blocks Building Blocks API intermediates Aromatics