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Anti-G3BP1, Anti-GAP SH3 domain-binding protein, Anti-HDH-VIII, Anti-human DNA helicase VIII, Anti-Ras-GTPase-activating protein SH3-domain binding protein 1

Anti-G3BP1, Anti-GAP SH3 domain-binding protein, Anti-HDH-VIII, Anti-human DNA helicase VIII, Anti-Ras-GTPase-activating protein SH3-domain binding protein 1 Structure
Anti-G3BP1, Anti-GAP SH3 domain-binding protein, Anti-HDH-VIII, Anti-human DNA helicase VIII, Anti-Ras-GTPase-activating protein SH3-domain binding protein 1 structure
CAS No.
Chemical Name:
Anti-G3BP1, Anti-GAP SH3 domain-binding protein, Anti-HDH-VIII, Anti-human DNA helicase VIII, Anti-Ras-GTPase-activating protein SH3-domain binding protein 1
Synonyms
Anti-G3BP1;Anti-HDH-VIII;Anti-human DNA helicase VIII;Anti-GAP SH3 domain-binding protein;Anti-ATP-dependent DNA helicase VIII;Anti-GAP SH3 domain-binding protein 1;Anti-G3BP1 antibody produced in rabbit;Anti-G3BP antibody produced in rabbit;Monoclonal Anti-G3BP antibody produced in mouse;Anti-Ras GTPase-activating protein-binding protein 1
CBNumber:
CB32101401
Molecular Formula:
Molecular Weight:
0
MDL Number:
MFCD02262927
MOL File:
Mol file
Last updated:2023-04-23 13:52:06
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Anti-G3BP1, Anti-GAP SH3 domain-binding protein, Anti-HDH-VIII, Anti-human DNA helicase VIII, Anti-Ras-GTPase-activating protein SH3-domain binding protein 1 Properties

storage temp. -20°C
form buffered aqueous glycerol solution

Anti-G3BP1, Anti-GAP SH3 domain-binding protein, Anti-HDH-VIII, Anti-human DNA helicase VIII, Anti-Ras-GTPase-activating protein SH3-domain binding protein 1 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich WH0010146M1 Monoclonal Anti-G3BP antibody produced in mouse clone 2F3, purified immunoglobulin, buffered aqueous solution 100μG $524 2024-03-01 Buy
Sigma-Aldrich SAB4500043 Anti-G3BP-1 antibody produced in rabbit affinity isolated antibody 100μG $506 2024-03-01 Buy
Sigma-Aldrich G8046 Anti-phospho-G3BP (pSer149) antibody produced in rabbit ~1.0?mg/mL, affinity isolated antibody, buffered aqueous solution 200μL $334.8 2024-03-01 Buy
Sigma-Aldrich G6046 Anti-G3BP antibody produced in rabbit ~1.0?mg/mL, affinity isolated antibody, buffered aqueous solution 200μL $334.8 2024-03-01 Buy
Sigma-Aldrich AV37713 Anti-G3BP antibody produced in rabbit IgG fraction of antiserum 100μL $443 2024-03-01 Buy
Product number Packaging Price Buy
WH0010146M1 100μG $524 Buy
SAB4500043 100μG $506 Buy
G8046 200μL $334.8 Buy
G6046 200μL $334.8 Buy
AV37713 100μL $443 Buy

Anti-G3BP1, Anti-GAP SH3 domain-binding protein, Anti-HDH-VIII, Anti-human DNA helicase VIII, Anti-Ras-GTPase-activating protein SH3-domain binding protein 1 Chemical Properties,Uses,Production

Uses

Anti-phospho-G3BP (pSer149) antibody produced in rabbit is suitable for western blotting at a working concentration of 5-10μg/mL using whole extract of human K562 and HeLa cells.

Uses

Anti-G3BP antibody produced in rabbit has been used in co-immunoprecipitation assay.

General Description

G3BP is a RNA-binding protein that contains a RNA binding domain, the RRM-type domain, at the carboxyl-terminal. The N-terminal domain is homologous to nuclear transporter factor 2 (NTF2) and the central domain is rich in acidic residues. The RRM domain is involved in the binding of G3BP to specific RNA sequences. This helps G3BP to function as a CA dinucleotide-specific endoribonuclease. G3BP′s subcellular localization and protein-protein interactions are mediated by the phosphorylation of G3BP at Ser149, near NTF2-like domain. G3BP is found in abundance in many kinds of malignant tumors such as lung, colon, gastric, and breast cancer.

Biochem/physiol Actions

G3BP (Ras-GTPase-activating protein SH3 domain binding protein 1) is a endoribonuclease that is phosphorylation-dependent and specific to single strand. It cleaves between cytosine and adenine (CA). It binds to the SH3 domain of RasGAP. It forms a link between RasGAP-mediated signaling pathway and RNA turnover. G3BP is required for the assembly of stress granules (SGs), which are involved in the regulation of mRNA metabolism during stress. It may be used as a cytoplasmic SG marker.

Anti-G3BP1, Anti-GAP SH3 domain-binding protein, Anti-HDH-VIII, Anti-human DNA helicase VIII, Anti-Ras-GTPase-activating protein SH3-domain binding protein 1 Preparation Products And Raw materials

Raw materials

Preparation Products

Anti-G3BP1, Anti-GAP SH3 domain-binding protein, Anti-HDH-VIII, Anti-human DNA helicase VIII, Anti-Ras-GTPase-activating protein SH3-domain binding protein 1 Suppliers

Global( 22)Suppliers
Supplier Tel Email Country ProdList Advantage
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Shanghai guandao biology engineering co., ltd 18818239863 18818239863 3171921642@qq.com China 8884 58
Supplier Advantage
Sigma-Aldrich 80
Shanghai guandao biology engineering co., ltd 58
Anti-G3BP antibody produced in rabbit Anti-G3BP1, Anti-GAP SH3 domain-binding protein, Anti-HDH-VIII, Anti-human DNA helicase VIII, Anti-Ras-GTPase-activating protein SH3-domain binding protein 1 Anti-phospho-G3BP (pSer149) antibody produced in rabbit Anti-ATP-dependent DNA helicase VIII Anti-G3BP1 antibody produced in rabbit Anti-GAP SH3 domain-binding protein 1 Anti-Ras GTPase-activating protein-binding protein 1 Anti-Ras-GTPase-activating protein SH3-domain-binding protein Monoclonal Anti-G3BP antibody produced in mouse Anti-G3BP1 Anti-GAP SH3 domain-binding protein Anti-HDH-VIII Anti-human DNA helicase VIII Anti-Ras-GTPase-activating protein SH3-domain binding protein 1