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(R)-(+)-1-(1-Naphthyl)ethylamine

CAS No.
3886-70-2
Chemical Name:
(R)-(+)-1-(1-Naphthyl)ethylamine
Synonyms
(R)-1-(1-NAPHTHYL)ETHYLAMINE;(R)-1-(NAPHTHALEN-1-YL)ETHANAMINE;CINACALCET intermediate;C12Hj3N;(R)-(+)-ALPH;Cinacalcet-21;RNEA IMPURITY;R-Napthylethylamine;Cinacalce Impurity A;Cinacalcet Impurity A
CBNumber:
CB3210204
Molecular Formula:
C12H13N
Molecular Weight:
171.24
MDL Number:
MFCD00064114
MOL File:
3886-70-2.mol
MSDS File:
SDS
Last updated:2024-01-08 10:00:16

(R)-(+)-1-(1-Naphthyl)ethylamine Properties

Melting point 135-136 °C
Boiling point 153 °C11 mm Hg(lit.)
alpha 60 º (c=2, CH3OH)
Density 1.067 g/mL at 20 °C(lit.)
refractive index n20/D 1.623(lit.)
Flash point >230 °F
storage temp. 2-8°C
solubility Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
form Liquid
pka 9.26±0.40(Predicted)
Specific Gravity 1.07
color brown
optical activity [α]20/D +55°, c = 2 in ethanol
Water Solubility Soluble in water (<10/l).
Sensitive Air Sensitive
BRN 2208025
Stability Stable. Air-sensitive. Incompatible with acids, oxidizing agents, acid anhydrides, chloroformates, acid chlorides.
InChIKey RTCUCQWIICFPOD-SECBINFHSA-N
CAS DataBase Reference 3886-70-2(CAS DataBase Reference)
EPA Substance Registry System 1-Naphthalenemethanamine, .alpha.-methyl-, (.alpha.R)- (3886-70-2)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
RIDADR  2735
WGK Germany  3
RTECS  QJ6963000
10-34
TSCA  Yes
HazardClass  8
PackingGroup  II
HS Code  29211990
NFPA 704
0
3 0

(R)-(+)-1-(1-Naphthyl)ethylamine price More Price(37)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 237442 (R)-(+)-1-(1-Naphthyl)ethylamine ≥99% 3886-70-2 1g $66.5 2024-03-01 Buy
Sigma-Aldrich 237442 (R)-(+)-1-(1-Naphthyl)ethylamine ≥99% 3886-70-2 5g $148 2024-03-01 Buy
TCI Chemical N0482 (R)-(+)-1-(1-Naphthyl)ethylamine >99.0%(GC) 3886-70-2 1g $43 2024-03-01 Buy
TCI Chemical N0482 (R)-(+)-1-(1-Naphthyl)ethylamine >99.0%(GC) 3886-70-2 5g $126 2024-03-01 Buy
Alfa Aesar A16918 (R)-(+)-1-(1-Naphthyl)ethylamine, 99% 3886-70-2 5g $133.65 2024-03-01 Buy
Product number Packaging Price Buy
237442 1g $66.5 Buy
237442 5g $148 Buy
N0482 1g $43 Buy
N0482 5g $126 Buy
A16918 5g $133.65 Buy

(R)-(+)-1-(1-Naphthyl)ethylamine Chemical Properties,Uses,Production

Chemical Properties

Colorless to light yellow liqui

Uses

It is used in chiral synthesis in organic reactions including the synthesis of β-amino acids and the enantioselective of ketones to nitroolefins. Also used as absolute configuration of primary amines determined using chiral (2-nitrophenyl)proline amides and H NMR.

Uses

(R)-(+)-1-(1-Naphthyl)ethylamine is used in chiral synthesis in organic reactions including the synthesis of β-amino acids and the enantioselective of ketones to nitroolefins.

Application

Absolute configuration of primary amines determined using chiral (2-nitrophenyl)proline amides and 1H NMR.

General Description

(R)-(+)-1-(1-Naphthyl)ethylamine is a chiral derivatization reagent useful for all gas chromatography (GC) applications in the chiral field. It is specially selected to meet the requirements for derivatization reagents for enantiomeric excess determinations.

Purification Methods

Purify the amine by distillation in a good vacuum. [Mori et al. Tetrahedron 37 1343 1981, cf Wilson in Topics Stereochem (Allinger and Eliel eds) v o l 6 135 1971, Fredga et al. Acta Chem Scand 11 1609 1957.] The hydrochlorides crystallise from H2O [] D 18 ±3.9o (c 3, H2O), and the sulfates recrystallise from H2O as tetrahydrates m 230-232o. The RS-amine has b 153o/11mm, 156o/15mm, 183.5o/41mm [Blicke & Maxwell J Am Chem Soc 6 1 1780 1939]. [Beilstein 12 III 3111.]

42882-31-5
3886-70-2
Synthesis of (R)-(+)-1-(1-Naphthyl)ethylamine from (+/-)1-(1-Naphthyl)ethylamine
Global( 531)Suppliers
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Yangzhou Qinyuan Pharmatech Co.,ltd
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View Lastest Price from (R)-(+)-1-(1-Naphthyl)ethylamine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(R)-(+)-1-(1-Naphthyl)ethylamine pictures 2024-03-19 (R)-(+)-1-(1-Naphthyl)ethylamine
3886-70-2
US $0.00 / KG 1KG ≥98% 100mt/year Jinan Finer Chemical Co., Ltd
(R)-(+)-1-(1-Naphthyl)ethylamine pictures 2023-10-07 (R)-(+)-1-(1-Naphthyl)ethylamine
3886-70-2
US $0.00 / kg 1kg 0.99 20tons Hebei Yanxi Chemical Co., Ltd.
(R)-(+)-1-(1-Naphthyl)ethylamine pictures 2023-07-27 (R)-(+)-1-(1-Naphthyl)ethylamine
3886-70-2
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd
(R) 1-(1-NAPTHYL)ETHYLAMINE (R)-(+)-1-(1-NAPHTHYL)ETHYLAMINE (R)-(+)-1-(NAPHTHYL)ETHYLAMINE (R)-(+)-A-(1-NAPHTHYL)ETHYLAMINE (R)-(+)-ALPHA-(1-AMINOETHYL)NAPHTHALENE (R)-(+)-ALPHA-(1-NAPHTHYL)ETHYLAMINE D-A-(1-NAPHTHYL)ETHYLAMINE (+)-1-[(R)-1-Aminoethyl]naphthalene (1R)-1-(1-Naphthyl)ethanamine (R)-α-Methylnaphthalene-1-methanamine (αR)-α-(1-Naphthyl)ethanamine [R,(+)]-α-Methyl-1-naphthalenemethanamine 1-Naphthalenemethanamine, alpha-methyl-, (R)- (theta)-1-naphthalenemethanamine Cinacalcet Intermediate 3 (R)-(+)-alpha-(Naphthalen-1-yl)ethanaMine (R)-(+)-ALPHA-(1-AMINOETHYL)NAPHT (1R)-(+)-1-(Naphth-1-yl)ethylamine (R)-(+)-alpha-(1-Naphthyl)ethylaMine, 99+% 1GR (R)-1-(naphthalene-1-yl)ethanaMine (R)-(+)-1-(1-Naphthyl)ethylaMine SynonyMs R-(+)-alpha-(1-Naphthyl)ethylaMine (1R)-1-(naphthalen-1-yl)ethan-1-amine Cinacalcet Impurity A (R)-(+)-1-(1-phthyl)ethylamine (R)-1-(1-naphthyl)ethylamine,99%e.e. (1R)-(1-NAPHTHALEN-1-YL)ETHANAMINE (theta)-1-naphthalenemethanamin (R)-(+)-α-Methyl-1-naphthalenemethylamine R-PLUS-A-1-NAPHTHYL-ETHYLAMINE (R)-(+)-1-(1-NAPHTHYL)ETHYLAMINE 99% (R)-(+)-1-(Napthyl)ethylamine, 99% (R)-(+)-alpha-(1-Naphthyl)ethylamine, 99+% 1-Naphthalenemethanamine, .alpha.-methyl-, (.alpha.R)- (R)-(+)-1-(Naphth-1-yl)ethylamine (R)-(+)-1-(1-Naphthyl)ethylamine, ChiPros 99+%, ee 98+% (R)-(+)-α-(1-Naphthyl)ethylamine, 99+% R-(+)-NAPHTHYLETHYLAMINE (R)- (+)--(1-NAPHTHYL) ETHYLAMINE 98% Cinacalce Impurity A R-NAPHTHALENEYL METHYL-1-PHENYLETHYLAMINE (R)-(+)-ALPH (R)-1-(Naphthalen-1-yl)ethanamine HCl R-Napthylethylamine (R)-(+)-1-(1-Naphthyl)ethylami Cinacalcet-21 (R)-(+)-1-(1-NaphthyL (R)-(+)-1-(1-Naphthyl)ethylamine> (R)-(+)-1-(1-Naphthyl)ethylamine Cinacalcet Impurity A 1-Naphthalenemethanamine, α-methyl-, (αR)- (R)-(+)-α-(1-Naphthyl)ethylamine (R)-(+)-1-(1-Naphthyl)ethylamine ISO 9001:2015 REACH (R)-1-(Naphthalen-1-yl)ethanamine (Cinacalcet Impurity) Cinacalcet Impurity A (Cinacalcet Amine Impurity) Cinacalcet Impurity AQ: What is Cinacalcet Impurity A Q: What is the CAS Number of Cinacalcet Impurity A Q: What is the storage condition of Cinacalcet Impurity A Q: What are the applications of Cinacalcet Impurity A (R)-1-(1-NAPHTHYL)ETHYLAMINE (R)-1-(NAPHTHALEN-1-YL)ETHANAMINE CINACALCET intermediate (R)-(+)-α-Methyl-1-naphthalenemethylamine