4'-(2-Methylpropyl)acetophenone
- CAS No.
- 38861-78-8
- Chemical Name:
- 4'-(2-Methylpropyl)acetophenone
- Synonyms
- 1-(4-ISOBUTYLPHENYL)ETHAN-1-ONE;4-ISOBUTYLACETOPHENONE;1-(4-ISOBUTYLPHENYL)ETHANONE;4-IBAP;Nsc173015;1Y1&1R DV1;Ibuprofen-4;IBUPROFEN IMP E;p-Isobutylacetoph;TIMTEC-BB SBB007668
- CBNumber:
- CB3210390
- Molecular Formula:
- C12H16O
- Molecular Weight:
- 176.25
- MDL Number:
- MFCD00027393
- MOL File:
- 38861-78-8.mol
Boiling point | 134-135°C 16mm |
---|---|
Density | 0,952 g/cm3 |
vapor pressure | 0.75Pa at 20℃ |
refractive index | 1.5180 |
Flash point | 54°C |
storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
solubility | soluble in Dichloromethane; Diethyl Ether; Ethyl Acetate; THF |
color | Colorless to Yellow |
Water Solubility | Miscible with chloroform and methanol. Slightly miscible with water. |
BRN | 1935275 |
InChI | InChI=1S/C12H16O/c1-9(2)8-11-4-6-12(7-5-11)10(3)13/h4-7,9H,8H2,1-3H3 |
InChIKey | KEAGRYYGYWZVPC-UHFFFAOYSA-N |
SMILES | C(=O)(C1=CC=C(CC(C)C)C=C1)C |
LogP | 3.4 at 23℃ |
CAS DataBase Reference | 38861-78-8(CAS DataBase Reference) |
FDA UNII | AML715RD20 |
NIST Chemistry Reference | 4'-(2-Methylpropyl)acetophenone(38861-78-8) |
EPA Substance Registry System | Ethanone, 1-[4-(2-methylpropyl)phenyl]- (38861-78-8) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07,GHS09 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H315-H317-H411 | |||||||||
Precautionary statements | P261-P264-P272-P273-P280-P302+P352 | |||||||||
Hazard Codes | Xn,N,Xi | |||||||||
Risk Statements | 10-40-52/53-43 | |||||||||
Safety Statements | 16-36-22-61-36/37 | |||||||||
RIDADR | 1224 | |||||||||
WGK Germany | 3 | |||||||||
TSCA | Yes | |||||||||
HazardClass | 3.2 | |||||||||
PackingGroup | III | |||||||||
HS Code | 29143990 | |||||||||
NFPA 704 |
|
4'-(2-Methylpropyl)acetophenone price More Price(30)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | PHR1146 | 4′-Isobutylacetophenone | 38861-78-8 | 500mg | $128 | 2024-03-01 | Buy |
Sigma-Aldrich | BP557 | 4′-Isobutylacetophenone British Pharmacopoeia (BP) Reference Standard | 38861-78-8 | 100MG | $222 | 2024-03-01 | Buy |
Sigma-Aldrich | 1335541 | Ibuprofen Related Compound C | 38861-78-8 | 3x0.2ml | $1380 | 2024-03-01 | Buy |
TCI Chemical | I0417 | 4'-Isobutylacetophenone >96.0%(GC) | 38861-78-8 | 25mL | $72 | 2024-03-01 | Buy |
TCI Chemical | I0417 | 4'-Isobutylacetophenone >96.0%(GC) | 38861-78-8 | 100mL | $197 | 2024-03-01 | Buy |
4'-(2-Methylpropyl)acetophenone Chemical Properties,Uses,Production
Chemical Properties
Clear Colourless Oil
Uses
4'-isobutylacetophenone is an important starting material employed in the production of pharmaceuticals such as ibuprofen. It is also utilized in proteomics research. It is used as an intermediate in organic synthesis.
Uses
A degradation product of Ibuprofen in tablets, which is a known toxin. Ibuprofen (I140000) impuritiy.
Preparation
Synthesis of 4-isobutylacetophenone: toluene and propylene are reacted with the participation of metal potassium, sodium carbonate and graphite, Alkylation on methyl to generate isobutylbenzene, Then with acetyl chloride in the participation of anhydrous aluminum trichloride to obtain the product.
General Description
4'-(2-Methylpropyl)acetophenone, also known as Ibuprofen EP Impurity E, is an impurity of ibuprofen. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID). It works by blocking your body's production of certain natural substances that cause inflammation.
4'-(2-Methylpropyl)acetophenone Preparation Products And Raw materials
Raw materials
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Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Guangzhou Tosun Pharmaceutical Limited | +8618922120635 | sales@toref-standards.com | China | 1000 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 14764 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21700 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | sales@sdzschem.com | China | 2931 | 58 |
Cangzhou Wanyou New Material Technology Co.,Ltd | 18631714998 | sales@czwytech.com | CHINA | 906 | 58 |
Changzhou Ditong Chemical Co.,Ltd | +86-0519-88299272 | info@edengenechem.com | China | 2169 | 58 |
Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14336 | 58 |
Hebei shuoxi biotechnology co. LTD | +8613081092107 | CHINA | 968 | 58 |
View Lastest Price from 4'-(2-Methylpropyl)acetophenone manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2023-07-11 | Ibuprofen EP Impurity E
38861-78-8
|
US $0.00 / mg | 1mg | above 96% | 50kg | Guangzhou Tosun Pharmaceutical Limited | ||
2023-06-26 | 4'-(2-Methylpropyl)acetophenone
38861-78-8
|
US $150.00 / KG | 1KG | 99 | 20tons | Hebei Mingeng Biotechnology Co., Ltd | ||
2022-11-02 | 4'-(2-Methylpropyl)acetophenone
38861-78-8
|
US $200.00 / g | 10g | 99% | 1000t/month | Hebei Best Biological Technology Co., Ltd |
- Ibuprofen EP Impurity E
38861-78-8
- US $0.00 / mg
- above 96%
- Guangzhou Tosun Pharmaceutical Limited
- 4'-(2-Methylpropyl)acetophenone
38861-78-8
- US $150.00 / KG
- 99
- Hebei Mingeng Biotechnology Co., Ltd
- 4'-(2-Methylpropyl)acetophenone
38861-78-8
- US $200.00 / g
- 99%
- Hebei Best Biological Technology Co., Ltd
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