ChemicalBook >> CAS DataBase List >>4'-(2-Methylpropyl)acetophenone

4'-(2-Methylpropyl)acetophenone

CAS No.
38861-78-8
Chemical Name:
4'-(2-Methylpropyl)acetophenone
Synonyms
1-(4-ISOBUTYLPHENYL)ETHAN-1-ONE;4-ISOBUTYLACETOPHENONE;1-(4-ISOBUTYLPHENYL)ETHANONE;4-IBAP;Nsc173015;1Y1&1R DV1;Ibuprofen-4;IBUPROFEN IMP E;p-Isobutylacetoph;TIMTEC-BB SBB007668
CBNumber:
CB3210390
Molecular Formula:
C12H16O
Molecular Weight:
176.25
MDL Number:
MFCD00027393
MOL File:
38861-78-8.mol
Last updated:2023-07-11 11:04:37

4'-(2-Methylpropyl)acetophenone Properties

Boiling point 134-135°C 16mm
Density 0,952 g/cm3
vapor pressure 0.75Pa at 20℃
refractive index 1.5180
Flash point 54°C
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility soluble in Dichloromethane; Diethyl Ether; Ethyl Acetate; THF
color Colorless to Yellow
Water Solubility Miscible with chloroform and methanol. Slightly miscible with water.
BRN 1935275
InChI InChI=1S/C12H16O/c1-9(2)8-11-4-6-12(7-5-11)10(3)13/h4-7,9H,8H2,1-3H3
InChIKey KEAGRYYGYWZVPC-UHFFFAOYSA-N
SMILES C(=O)(C1=CC=C(CC(C)C)C=C1)C
LogP 3.4 at 23℃
CAS DataBase Reference 38861-78-8(CAS DataBase Reference)
FDA UNII AML715RD20
NIST Chemistry Reference 4'-(2-Methylpropyl)acetophenone(38861-78-8)
EPA Substance Registry System Ethanone, 1-[4-(2-methylpropyl)phenyl]- (38861-78-8)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS09
Signal word  Warning
Hazard statements  H315-H317-H411
Precautionary statements  P261-P264-P272-P273-P280-P302+P352
Hazard Codes  Xn,N,Xi
Risk Statements  10-40-52/53-43
Safety Statements  16-36-22-61-36/37
RIDADR  1224
WGK Germany  3
TSCA  Yes
HazardClass  3.2
PackingGroup  III
HS Code  29143990
NFPA 704
2
2 0

4'-(2-Methylpropyl)acetophenone price More Price(30)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHR1146 4′-Isobutylacetophenone 38861-78-8 500mg $128 2024-03-01 Buy
Sigma-Aldrich BP557 4′-Isobutylacetophenone British Pharmacopoeia (BP) Reference Standard 38861-78-8 100MG $222 2024-03-01 Buy
Sigma-Aldrich 1335541 Ibuprofen Related Compound C 38861-78-8 3x0.2ml $1380 2024-03-01 Buy
TCI Chemical I0417 4'-Isobutylacetophenone >96.0%(GC) 38861-78-8 25mL $72 2024-03-01 Buy
TCI Chemical I0417 4'-Isobutylacetophenone >96.0%(GC) 38861-78-8 100mL $197 2024-03-01 Buy
Product number Packaging Price Buy
PHR1146 500mg $128 Buy
BP557 100MG $222 Buy
1335541 3x0.2ml $1380 Buy
I0417 25mL $72 Buy
I0417 100mL $197 Buy

4'-(2-Methylpropyl)acetophenone Chemical Properties,Uses,Production

Chemical Properties

Clear Colourless Oil

Uses

4'-isobutylacetophenone is an important starting material employed in the production of pharmaceuticals such as ibuprofen. It is also utilized in proteomics research. It is used as an intermediate in organic synthesis.

Uses

A degradation product of Ibuprofen in tablets, which is a known toxin. Ibuprofen (I140000) impuritiy.

Preparation

Synthesis of 4-isobutylacetophenone: toluene and propylene are reacted with the participation of metal potassium, sodium carbonate and graphite, Alkylation on methyl to generate isobutylbenzene, Then with acetyl chloride in the participation of anhydrous aluminum trichloride to obtain the product.
Synthesis of 4-isobutylacetophenone

General Description

4'-(2-Methylpropyl)acetophenone, also known as Ibuprofen EP Impurity E, is an impurity of ibuprofen. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID). It works by blocking your body's production of certain natural substances that cause inflammation.

Global( 338)Suppliers
Supplier Tel Email Country ProdList Advantage
Guangzhou Tosun Pharmaceutical Limited
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Capot Chemical Co.,Ltd.
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Changzhou Ditong Chemical Co.,Ltd
+86-0519-88299272 info@edengenechem.com China 2169 58
Standardpharm Co. Ltd.
86-714-3992388 overseasales1@yongstandards.com United States 14336 58
Hebei shuoxi biotechnology co. LTD
+8613081092107 CHINA 968 58

View Lastest Price from 4'-(2-Methylpropyl)acetophenone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Ibuprofen EP Impurity E pictures 2023-07-11 Ibuprofen EP Impurity E
38861-78-8
US $0.00 / mg 1mg above 96% 50kg Guangzhou Tosun Pharmaceutical Limited
4'-(2-Methylpropyl)acetophenone pictures 2023-06-26 4'-(2-Methylpropyl)acetophenone
38861-78-8
US $150.00 / KG 1KG 99 20tons Hebei Mingeng Biotechnology Co., Ltd
4'-(2-Methylpropyl)acetophenone pictures 2022-11-02 4'-(2-Methylpropyl)acetophenone
38861-78-8
US $200.00 / g 10g 99% 1000t/month Hebei Best Biological Technology Co., Ltd
Imp. E:1-(4-isobutylphenyl)ethanone TIMTEC-BB SBB007668 P-ISO-BUTYLACETOPHENONE IBUPROFEN IMPURITY E IBUPROFEN IMP E ISOBUTYL ACETOPHENONE 4'-Isobutylacetophenone, 97+% 4'-ISOBUTYLACETOPHENONE 1-[4-(2-METHYLPROPYL)PHENYL]ETHANONE 1-[4-(2-methylpropyl)phenyl]-ethanon 4-Isobutylacetaphenone 1-[4-(2-methylpropyl)phenyl]ethan-1-one 1-(4-(2-METHYLPROPYL)PHENYL)ETNANONE 4'-(2-Methylpropyl)acetophenone 4-lsobutylacetophenone Acetophenone, 4-isobutyl- Ethanone, 1-[4-(2-methylpropyl)phenyl]- Nsc173015 p-Isobutylacetoph Ibuprofen IMpurity-E(EP) 4'-(2-Methylpropyl)a 1-[4-(2-Methylprop-1-yl)phenyl]ethan-1-one, 1-(4-Isobutylphenyl)ethan-1-one Ibuprofen Related CoMpound C, USP 3 ampules) (4-isobutylacetophenone) Ibuprofen Related Compound C (0.2 mL/ampule 1-[4-(2-Methylpropyl)phenyl]-1-ethanone 1-Acetyl-4-isobutylbenzene p-Acetylisobutylbenzene 4-ISOBUTYLACETOPHENONE(Ibuprofen Related Compound C)(Ibuprofen Impurity E) 1Y1&1R DV1 Ibuprofen-4 Ibuprofen EP Impurity E 4-IBAP Ibuprofen USP Related Compound C Ibuprofen EP Impurity E:Ibuprofen Impurity E 4'-Isobutylacetophenone> 4-Isobutylacetophenone(Ibuprofen Impurity) Ibuprofen Impurity 5(Ibuprofen EP Impurity E) Ibuprofen Impurity E/4-isobutylacetophenone Ibuprofen EP Impurity E/ Ibuprofen Related Compound C Ibuprofen USP Related Compound CQ: What is Ibuprofen USP Related Compound C Q: What is the CAS Number of Ibuprofen USP Related Compound C Q: What is the storage condition of Ibuprofen USP Related Compound C Q: What are the applications of Ibuprofen USP Related Compound C 4-ISOBUTYLACETOPHENONE 1-(4-ISOBUTYLPHENYL)ETHAN-1-ONE 1-(4-ISOBUTYLPHENYL)ETHANONE Ibuprofen EP Impurit 38861-78-8 Aromatic Acetophenones & Derivatives (substituted) Aromatics, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals Aromatics Impurities Intermediates & Fine Chemicals Pharmaceuticals