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Tadalafil-d3

Tadalafil-d3
Tadalafil-d3 structure
CAS No.
960226-55-5
Chemical Name:
Tadalafil-d3
Synonyms
Tadalafil-d3;[2H3]-Tadalafil;PubChem ID: 46782966;Pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione, 6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-(methyl-d3)-, (6R,12aR)-
CBNumber:
CB32104260
Molecular Formula:
C22H18N3O4
Formula Weight:
388.39602
MOL File:
960226-55-5.mol

Tadalafil-d3 Properties

Melting point:
281-283°C
storage temp. 
-20°C Freezer

Tadalafil-d3 price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 25030 Tadalafil-d3 ≥99% deuterated forms (d1-d3) 960226-55-5 1mg $145 2021-12-16 Buy
Cayman Chemical 25030 Tadalafil-d3 ≥99% deuterated forms (d1-d3) 960226-55-5 5mg $580 2021-12-16 Buy
TRC T004510 Tadalafil-d3 960226-55-5 10mg $1390 2021-12-16 Buy
American Custom Chemicals Corporation RDL0005317 TADALAFIL-D3 95.00% 960226-55-5 10MG $1963.5 2021-12-16 Buy
American Custom Chemicals Corporation RDL0005317 TADALAFIL-D3 95.00% 960226-55-5 1MG $750.75 2021-12-16 Buy

Tadalafil-d3 Chemical Properties,Uses,Production

Description

Tadalafil-d3 is intended for use as an internal standard for the quantification of tadalafil (Item No. 14024) by GC- or LC-MS. Tadalafil is a potent inhibitor of phosphodiesterase 5 (PDE5; IC50 = 1.2 nM). It is selective for PDE5 over PDE1-4 and 7-10 (IC50s = 9.2-280 μM), however, it does also inhibit PDE11 (IC50 = 11 nM). In vivo, tadalafil (10 mg/kg) decreases production of the proinflammatory cytokines TNF-α, IL-1β, and IL-6 and improves renal function in a rat model of ischemia/reperfusion injury. It also reduces development of tobacco smoke-induced emphysema and pulmonary hypertension in mice. Formulations containing tadalafil have been used to treat erectile dysfunction, pulmonary arterial hypertension, and lower urinary tract dysfunction.

Chemical Properties

Tadalafil-d3 is White Solid

Uses

Tadalafil-d3 is used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor. Intended for use as an internal standard for the quantification of Tadalafil by GC- or LC-mass spectrometry.

Uses

Tadalafil is used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor.

Tadalafil-d3 Preparation Products And Raw materials

Raw materials

Preparation Products


Tadalafil-d3 Suppliers

Global( 34)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 linda@hubeijusheng.com CHINA 28229 58
BOC Sciences
1-631-485-4226
1-631-614-7828 inquiry@bocsci.com United States 19752 58
J & K SCIENTIFIC LTD. 400-666-7788 010-82848833-
86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96815 76
Chemsky(shanghai)International Co.,Ltd. 021-50135380
shchemsky@sina.com China 32358 50
Cato Research Chemicals Inc. +1-541-2553640
+1-541-2553641 info@cato-chem.com China 1958 55
ChemStrong Scientific Co.,Ltd 15920483169 0755-66853366-
sales@chem-strong.com China 26481 56
Shanghai EFE Biological Technology Co., Ltd. 021-65675885
021-65675885 info@efebio.com China 9918 58
Clearsynth Canada Inc. +1.415.685.4395
+1.415.685.4395 enquiry@clearsynth.com Canada 912 58
Shanghai Champ Biopharmaceuticals Co., Ltd. 13585780846
sales@champchem.com; China 317 58
Hubei Yangxin Medical Technology Co., Ltd. 15391658522
QQ:2853117752 2853117752@qq.com China 15793 55

960226-55-5(Tadalafil-d3)Related Search:


  • Tadalafil-d3
  • Pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione, 6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-(methyl-d3)-, (6R,12aR)-
  • PubChem ID: 46782966
  • [2H3]-Tadalafil
  • 960226-55-5
  • C22H16N3O4D3
  • Chiral Reagents
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Isotope Labelled Compounds
  • Pharmaceuticals
  • Intermediates & Fine Chemicals,Chiral Reagents
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