ChemicalBook >> CAS DataBase List >>Tadalafil-d3
Tadalafil-d3
- CAS No.
- 960226-55-5
- Chemical Name:
- Tadalafil-d3
- Synonyms
- Tadalafil-d3;[2H3]-Tadalafil;PubChem ID: 46782966;Pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione, 6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-(methyl-d3)-, (6R,12aR)-;Tadalafil D3Q: What is Tadalafil D3 Q: What is the CAS Number of Tadalafil D3 Q: What is the storage condition of Tadalafil D3 Q: What are the applications of Tadalafil D3
- CBNumber:
- CB32104260
- Molecular Formula:
- C22H18N3O4
- Molecular Weight:
- 388.39602
- MDL Number:
- MFCD04116200
- MOL File:
- 960226-55-5.mol
- MSDS File:
- SDS
Last updated:2023-09-05 10:22:03
| Melting point | 281-283°C |
|---|---|
| storage temp. | -20°C Freezer |
| solubility | Chloroform (Slightly), DMSO (Slightly) |
| form | Solid |
| color | White to Off-White |
| Stability | Unstable in Methanol |
| InChI | InChI=1/C22H19N3O4/c1-24-10-19(26)25-16(22(24)27)9-14-13-4-2-3-5-15(13)23-20(14)21(25)12-6-7-17-18(8-12)29-11-28-17/h2-8,16,21,23H,9-11H2,1H3/t16-,21+/s3 |
| InChIKey | WOXKDUGGOYFFRN-PDIFIXMTNA-N |
| SMILES | c12c3ccccc3nc1[C@H](c1cc3OCOc3cc1)N1C(=O)CN(C)C(=O)[C@H]1C2 |&1:9,27,r| |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501 | |||||||||
| NFPA 704 |
|
Tadalafil-d3 price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 25030 | Tadalafil-d3 ≥99% deuterated forms (d1-d3) | 960226-55-5 | 1mg | $178 | 2024-03-01 | Buy |
| Cayman Chemical | 25030 | Tadalafil-d3 ≥99% deuterated forms (d1-d3) | 960226-55-5 | 5mg | $704 | 2024-03-01 | Buy |
| TRC | T004510 | Tadalafil-d3 | 960226-55-5 | 10mg | $1390 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | RDL0005317 | TADALAFIL-D3 95.00% | 960226-55-5 | 10MG | $1963.5 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | RDL0005317 | TADALAFIL-D3 95.00% | 960226-55-5 | 1MG | $750.75 | 2021-12-16 | Buy |
Tadalafil-d3 Chemical Properties,Uses,Production
Description
Tadalafil-d3 is intended for use as an internal standard for the quantification of tadalafil by GC- or LC-MS. Tadalafil is a potent inhibitor of phosphodiesterase 5 (PDE5; IC50 = 1.2 nM). It is selective for PDE5 over PDE1-4 and 7-10 (IC50s = 9.2-280 μM), however, it does also inhibit PDE11 (IC50 = 11 nM). In vivo, tadalafil (10 mg/kg) decreases production of the proinflammatory cytokines TNF-α, IL-1β, and IL-6 and improves renal function in a rat model of ischemia/reperfusion injury. It also reduces development of tobacco smoke-induced emphysema and pulmonary hypertension in mice. Formulations containing tadalafil have been used to treat erectile dysfunction, pulmonary arterial hypertension, and lower urinary tract dysfunction.
Chemical Properties
Tadalafil-d3 is White Solid
Uses
Tadalafil-d3 is used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor. Intended for use as an internal standard for the quantification of Tadalafil by GC- or LC-mass spectrometry.
Uses
Tadalafil is used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor.
Tadalafil-d3 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 48)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| SIMSON PHARMA LIMITED | +91-8291074273 | k.das@simsonpharma.com | India | 228 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| BOC Sciences | -- | info@bocsci.com | USA | 0 | 65 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 94838 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| Daicel Chiral Technologies (China)CO.,LTD | 021-50460086-9 15921403865 | han_yajun@dctc.daicel.com | China | 6818 | 65 |
| Cato Research Chemicals Inc. | 020-81960175 | min.he@cato-chem.com | China | 1958 | 55 |
| ChemStrong Scientific Co.,Ltd | 0755-66853366 13670046396 | sales@chem-strong.com | China | 17982 | 56 |
| Clearsynth Canada Inc. | +1.415.685.4395 | enquiry@clearsynth.com | Canada | 912 | 58 |
View Lastest Price from Tadalafil-d3 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-05-27 | Tadalafil-D3
960226-55-5
|
US $282.00-487.00 / mg | 10mg | 96% | 100 | Simson Pharma limited | |
 |
2023-05-27 | Tadalafil-D3
960226-55-5
|
US $0.00-0.00 / mg | 1mg | 96% | 50 mg | Simson Pharma limited |
-
- Tadalafil-D3
960226-55-5
- US $282.00-487.00 / mg
- 96%
- Simson Pharma limited
-
- Tadalafil-D3
960226-55-5
- US $0.00-0.00 / mg
- 96%
- Simson Pharma limited
960226-55-5(Tadalafil-d3)Related Search:
N-Ethyl Tadalafil
Tadalafil EP impurity E
Tadalafil iMpurity D
Tadalafil EP IMpurity F
ent-Tadalafil
tadalafi
cis-ent-Tadalafil
Tadalafil iMpurity C
cis-Tadalafil
(6R,trans)-6-(3,4-dihydroxyphenyl)-2,3,6,7,12,12a-hexahydro-2-Methyl-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione
1of4
Tadalafil-d3
Pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione, 6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-(methyl-d3)-, (6R,12aR)-
PubChem ID: 46782966
[2H3]-Tadalafil
Tadalafil D3Q: What is
Tadalafil D3 Q: What is the CAS Number of
Tadalafil D3 Q: What is the storage condition of
Tadalafil D3 Q: What are the applications of
Tadalafil D3
960226-55-5
C22H16N3O4D3
Chiral Reagents
Inhibitors
Intermediates & Fine Chemicals
Isotope Labelled Compounds
Pharmaceuticals
Intermediates & Fine Chemicals,Chiral Reagents