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Atropic acid

CAS No.
492-38-6
Chemical Name:
Atropic acid
Synonyms
NSC 20987;ATROPIC ACID;Atropic Acid >10029 ATROPIC ACID;2-PHENYLACRYLIC ACID;Cinacalcet ImpurityI;Α-PHENYLACRYLIC ACID;Atropic acid,492-38-6;2-Phenylpropenoic acid;Ipratropium Impurity D
CBNumber:
CB3224700
Molecular Formula:
C9H8O2
Molecular Weight:
148.16
MDL Number:
MFCD00046531
MOL File:
492-38-6.mol
MSDS File:
SDS
Last updated:2024-03-06 09:18:21

Atropic acid Properties

Melting point 106-107°
Boiling point bp ~267° with partial decompn
Density 1.0061 (rough estimate)
refractive index 1.5049 (estimate)
storage temp. 2-8°C
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka 3.86±0.11(Predicted)
color White to Off-White
Water Solubility 1.3g/L(20 ºC)
Merck 14,874
Stability Light Sensitive
InChIKey ONPJWQSDZCGSQM-UHFFFAOYSA-N
CAS DataBase Reference 492-38-6(CAS DataBase Reference)
FDA UNII TW16UA35S0
NIST Chemistry Reference Benzeneacetic acid, «alpha»-methylene-(492-38-6)
EPA Substance Registry System Benzeneacetic acid, .alpha.-methylene- (492-38-6)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
Risk Statements  36/37/38
Safety Statements  26-36/37/39
HS Code  29163990

Atropic acid price More Price(29)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical A2390 Atropic Acid >93.0%(GC) 492-38-6 5g $55 2024-03-01 Buy
TCI Chemical A2390 Atropic Acid >93.0%(GC) 492-38-6 25g $189 2024-03-01 Buy
TRC A793850 Atropic Acid 492-38-6 100mg $65 2021-12-16 Buy
TRC A793850 Atropic Acid 492-38-6 250mg $80 2021-12-16 Buy
TRC A793850 Atropic Acid 492-38-6 1g $105 2021-12-16 Buy
Product number Packaging Price Buy
A2390 5g $55 Buy
A2390 25g $189 Buy
A793850 100mg $65 Buy
A793850 250mg $80 Buy
A793850 1g $105 Buy

Atropic acid Chemical Properties,Uses,Production

Chemical Properties

White to Off-White Solid.

Uses

Atropic acid is an Impurity of Ipratropium bromide and Atropine Sulfate. Atropic acid and β,β-dimethylatropic acid are plant growth regulators.

Preparation

The synthesis of atropic acid involves several steps. Firstly, tropic acid is oxidized with hot KMnO4 to form benzoic acid. Secondly, tropic acid reacted with HBr to produce C9H9O2Br. Thirdly, C9H9O2Br is reacted with alcoholic KOH to yield atropic acid, C9H8O2. Finally, atropic acid is catalytically hydrogenated to form hydratropic acid, C9H10O2.

Reactions

Atropic acid is formed by the dehydration of tropic acid. Hence addition of water to atropic acid gives tropic acid.
Atropic acid, on oxidation yields benzoic acid. The formation of benzoic acid reveals that atropic acid and tropic acid contain atleast one benzene nucleus with a side chain containing carboxylic acid in their structure.
atropic acid reaction
As atropic acid is an unsaturated acid it mean atropic acid may be either structure (I) or (II) .
Hence, the structure (II) is atropic acid which is confirmed by oxidation with KMnO4 to form phenylglyoxal.

124-38-9
536-74-3
492-38-6
Synthesis of Atropic acid from Carbon dioxide and Phenylacetylene

Atropic acid Preparation Products And Raw materials

Global( 270)Suppliers
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Shanxi Naipu Import and Export Co.,Ltd
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+8613567161161 info@karrypharma.com China 30 58
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Wuhan Boyuan Import & Export Co., LTD
+86-15175982296 15175982296; Mike@whby-chem.com China 983 58
Zhejiang ZETian Fine Chemicals Co. LTD
18957127338 stella@zetchem.com China 2141 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58

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View Lastest Price from Atropic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Phenylacrylic acid pictures 2024-01-08 2-Phenylacrylic acid
492-38-6
US $9.00 / KG 1KG 99% 50000tons Wuhan Boyuan Import & Export Co., LTD
2-Phenylacrylic acid pictures 2023-08-16 2-Phenylacrylic acid
492-38-6
US $80.00 / KG 1KG >99% 20tons Weijer International Trade (Hebei) Co., Ltd
2-Phenylacrylic acid pictures 2023-08-16 2-Phenylacrylic acid
492-38-6
US $80.00 / KG 1KG >99% 20tons Weijer International Trade (Hebei) Co., Ltd
2-Phenylpropenoic acid 2-PHENYLPROP-2-ENOIC ACID 2-PHENYLACRYLIC ACID ALPHA-PHENYLACRYLIC ACID alpha-Phenylacrylic acid 2-Phenylacrylic acid 2-Phenylprop-2-enoic acid ATROPIC ACID 2-Propenoic acid, 2-phenyl- Acrylic acid, 2-phenyl- alpha-Toluic acid, alpha-methylene- Benzeneacetic acide, alpha-methylene- Propenoic acid, 2-phenyl- α-methylene-α-toluic acid ATROPIC ACID / 2-PHENYLACRYLIC ACID 10029 ATROPIC ACID α-Methylenebenzeneacetic acid 2-Phenylprop-2-enoic acid, Atropic acid 2-Phenyl-2-propenoic Acid NSC 20987 Benzeneacetic acid, a-Methylene- Benzeneacetic acid, .alpha.-methylene- Ipratropium bromide Impurity D Cinacalcet ImpurityI Ipratropium EP Impurity D Ipratropium Bromide EP Impurity D (2-Phenyl Acrylic Acid) Ipratropium Bromide EP Impurity D 2-Phenylacrylic acid 95% Ipratropium Bromide Impurity 4(Ipratropium EP Impurity D) Ipratropium Impurity D Atropic Acid( Alpha-Phenylacrylic Acid ) Atropic Acid > 2-Phenylacrylic acid, 97%, for synthesis Benzeneacetic acid, α-methylene- Ipratropium Bromide Impurity 4(Ipratropium Bromide EP Impurity D) Α-PHENYLACRYLIC ACID Atropic acid,492-38-6 Benzeneacetic acid, α-methylene- 492-38-6 C9H8O2 CH2CC6H5COOH Aromatics, Impurities Pharmaceutical Intermediates