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2-Cyanobenzyl bromide

2-Cyanobenzyl bromide Structure
2-Cyanobenzyl bromide structure
CAS No.
22115-41-9
Chemical Name:
2-Cyanobenzyl bromide
Synonyms
2-(BROMOMETHYL)BENZONITRILE;ALPHA-BROMO-O-TOLUNITRILE;Ortho Cyano Benzyl Bromide;AKOS 92624;Alogliptin-2;AKOS BBS-00000052;Cyanobenzyl bromide;α-Bromo-o-toluntrile;A-BROMO-O-TOLUNITRILE;2-CYANOBENZYL BROMIDE
CBNumber:
CB3241402
Molecular Formula:
C8H6BrN
Molecular Weight:
196.04
MDL Number:
MFCD00001794
MOL File:
22115-41-9.mol
MSDS File:
SDS
Last updated:2024-03-22 14:56:24
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2-Cyanobenzyl bromide Properties

Melting point 72-74 °C(lit.)
Boiling point 111 °C / 1.5mmHg
Density 1.5466 (rough estimate)
refractive index 1.6550 (estimate)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
Water Solubility Slightly soluble in water
solubility Chloroform (Slightly), Ethyl Acetate (Slightly)
form Crystalline Powder or Chunks
color White to gray-brown
BRN 742605
InChIKey QGXNHCXKWFNKCG-UHFFFAOYSA-N
CAS DataBase Reference 22115-41-9(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS05
Signal word  Danger
Hazard statements  H314
Precautionary statements  P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363
Hazard Codes  C
Risk Statements  34
Safety Statements  26-36/37/39-45-28A
RIDADR  UN 3261 8/PG 2
WGK Germany  3
F  10-19-21
Hazard Note  Corrosive
HazardClass  8
PackingGroup  II
HS Code  29269090
NFPA 704
0
3 0

2-Cyanobenzyl bromide price More Price(39)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 144711 2-(Bromomethyl)benzonitrile ≥97% 22115-41-9 5g $49.1 2024-03-01 Buy
Sigma-Aldrich 144711 2-(Bromomethyl)benzonitrile ≥97% 22115-41-9 25g $64 2024-03-01 Buy
TCI Chemical C1556 2-Cyanobenzyl Bromide >98.0%(GC) 22115-41-9 10g $68 2024-03-01 Buy
TCI Chemical C1556 2-Cyanobenzyl Bromide >98.0%(GC) 22115-41-9 25g $132 2024-03-01 Buy
Alfa Aesar B24278 2-(Bromomethyl)benzonitrile, 98% 22115-41-9 25g $135.65 2024-03-01 Buy
Product number Packaging Price Buy
144711 5g $49.1 Buy
144711 25g $64 Buy
C1556 10g $68 Buy
C1556 25g $132 Buy
B24278 25g $135.65 Buy

2-Cyanobenzyl bromide Chemical Properties,Uses,Production

Description

2-(Bromomethyl)benzonitrile reacts with 2H-tetrazole in the presence of KOH to yield 4-[(2H-tetra-zol-2-yl)meth-yl]benzonitrile. It undergoes base-promoted condensation reaction with homophthalic anhydride to yield 6,11-dihydro-5H-indeno[1,2-c]isoquinolin-5-one.

Chemical Properties

White to light yellow crystal powder

Uses

2-(Bromomethyl)benzonitrile is an intermediate in the synthesis of Alogliptin, an oral antihyperglycemic agent that is a selective inhibitor of the enzyme dipeptidyl peptidase-4 (DPP-4). Antidiabetic agent.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package.

General Description

2-(Bromomethyl)benzonitrile reacts with 2H-tetrazole in the presence of KOH to yield 4-[(2H-tetra-zol-2-yl)meth-yl]benzonitrile. It undergoes base-promoted condensation reaction with homophthalic anhydride to yield 6,11-dihydro-5H-indeno[1,2-c]isoquinolin-5-one.

Purification Methods

Purify the nitrile by steam distillation. Extract the distillate with Et2O, dry the extract (Na2SO4), evaporate and distil the residue. The solidified distillate can be recrystallised from pet ether or cyclohexane. NMR (CDCl3) : 7.8-7.2 (m 4H), 4.62 (s, 2H), IR max 2238 cm1 . [Drory Chem Ber 24 2570 1891, Borsche et al. Chem Ber 74 685 1934, Buckley et al. Aust J Chem 22 594 1969, Beilstein 9 III 2312.] LACHRYMATORY.

2-Cyanobenzyl bromide Preparation Products And Raw materials

Raw materials

Preparation Products

2-[(6-Chloro-3,4-dihydro-3-Methyl-2,4-dioxo-1(2h)-pyriMidinyl)Methyl]benzonitrile 2-[(6-CHLORO-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)METHYL]BENZONITRILE 2-(Hydroxymethyl)benzonitrile Dibenzo[b,e]thiepin-11(6H)-one 2,3-dihydro-1-oxo-1H-indene-4-carbonitrile
2-[(2-formylpyrrol-1-yl)methyl]benzonitrile N-[2-(AMINOMETHYL)BENZYL]-N,N-DIETHYLAMINE 2-Cyanobenzyl acetate 2-(4-HYDROXY-PIPERIDIN-1-YLMETHYL)-BENZONITRILE

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2-Cyanobenzyl bromide Suppliers

Global( 514)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Yanxi Chemical Co., Ltd. 		+8617531190177 peter@yan-xi.com China 5993 58
Henan Bao Enluo International TradeCo.，LTD 		+86-17331933971 +86-17331933971 deasea125996@gmail.com China 2503 58
Zibo Hangyu Biotechnology Development Co., Ltd 		+86-0533-2185556 +8617865335152 Mandy@hangyubiotech.com China 11013 58
hebei hongtan Biotechnology Co., Ltd 		+86-86-1913198-3935 +8617331935328 sales03@chemcn.cn China 951 58
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21695 55
Hangzhou FandaChem Co.,Ltd. 		008657128800458; +8615858145714 fandachem@gmail.com China 9352 55
Nanjing ChemLin Chemical Industry Co., Ltd. 		025-83697070 product@chemlin.com.cn CHINA 3012 60
Shanghai Yingrui Biopharma Co., Ltd. 		+86-21-33585366 - 03@ sales03@shyrchem.com CHINA 738 60
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32480 60
Supplier Advantage
Hebei Yanxi Chemical Co., Ltd. 		58
Henan Bao Enluo International TradeCo.，LTD 		58
Zibo Hangyu Biotechnology Development Co., Ltd 		58
hebei hongtan Biotechnology Co., Ltd 		58
Capot Chemical Co.,Ltd. 		60
Henan Tianfu Chemical Co.,Ltd. 		55
Hangzhou FandaChem Co.,Ltd. 		55
Nanjing ChemLin Chemical Industry Co., Ltd. 		60
Shanghai Yingrui Biopharma Co., Ltd. 		60
ATK CHEMICAL COMPANY LIMITED 		60

View Lastest Price from 2-Cyanobenzyl bromide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Cyanobenzyl bromide pictures 2024-04-19 2-Cyanobenzyl bromide
22115-41-9
 US $42.00 / KG 1KG 99% 100MT Jinan Finer Chemical Co., Ltd
2-Cyanobenzyl bromide pictures 2024-04-12 2-Cyanobenzyl bromide
22115-41-9
 US $30.00 / kg 1kg 98% 2000kg hebei hongtan Biotechnology Co., Ltd
2-Cyanobenzyl bromide pictures 2024-01-04 2-Cyanobenzyl bromide
22115-41-9
 US $0.00-0.00 / kg 1kg 98% 1 ton Nanjing Fred Technology Co., Ltd

2-Cyanobenzyl bromide Spectrum

2-Cyanobenzyl bromide(22115-41-9)1HNMR2-Cyanobenzyl bromide(22115-41-9)IR2-Cyanobenzyl bromide(22115-41-9)FT-IR2-Cyanobenzyl bromide(22115-41-9)Raman

22115-41-9(2-Cyanobenzyl bromide)Related Search:

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Adjacent cyano benzyl broMide O-CYANOBENZYL BROMIDE ALPHA-BROMO-O-TOLUONITRILE AKOS 92624 AKOS BBS-00000052 A-BROMO-O-TOLUNITRILE alpha-bromo-ortho-tolunitrile 2-CYANOBENZYL BROMIDE 2-(Bromomethyl)benzonitrile >=97% α-Bromo-o-toluntrile a-Bromo-o-tolunitrile, (2-Cyanobenzyl bromide) ALPHA-BROMO-ORTHO-TOLUNITRILE, 97+% Alpha-Bromo-O-Tolunitrile98% Benzonitrile, 2-(bromomethyl)- à-bromo-o-tolunitrile α-bromo-o-tolunitrile 2-Cyanobenzyl bromide 98% 2-Cyanobenzylbromide98% 2-CYANIDE BENZYL BROMIDE 99+% 2-(Bromomethyl)benzonitrile, 97% - (See B24278) α-Bromo-o-tolunitrile, 2-Cyanobenzyl bromide 2-(bromomethy)benzonitrile 2-(Bromomethyl)benzonitrile,98% α-Bromo-o-tolunitrile ,97% -Cyano benzyl broMide (O-Cyano benzyl broMide) 2-(Bromomethyl)benzonitrile 98% 2-(Bromomethyl)benzonitrile alpha-Bromo-o-tolunitrile o-(Bromomethyl)benzonitrile (2-Cyanophenyl)Methyl broMide 2-Cyanobenzyl bromide 2-(Bromomethyl)benzonitrile o-Cyanobenzyl Bromid 2-(Bromomethyl)Benzonitrile Alogliptin-2 2-CyanobenzylBromide> Cyanobenzyl bromide alogliptin impurities160 alogliptin impurities13 alpha-Bromo-o-tolunitrile,2-Cyano benzyl bromide ALPHA-BROMO-O-TOLUNITRILE 2-(BROMOMETHYL)BENZONITRILE Ortho Cyano Benzyl Bromide 1-Pyrrolidinepropanoicacid,2,11-dioxo- Alpha bromo toluoyl nitrile (2-Cyanophenyl)methyl bromide (Alogliptin Impurity) Alogliptin intermediate 2-Cyanobenzyl bromide 22115-41-9 22115-14-9 2215-41-9 BrCH2C6H4CN Cyanides/Nitriles Organic Building Blocks Nitrogen Compounds C8 to C9 Building Blocks cyanide| alkyl bromide 22115-41-9