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GW 842166X

GW 842166X Structure
GW 842166X structure
CAS No.
666260-75-9
Chemical Name:
GW 842166X
Synonyms
CS-631;GW 842166;GW 842166X;GW842166X;GW 842166;GW842166X/GW-842166X;GW 842166X USP/EP/BP;2-(2,4-dichloroanilino)-N-(oxan-4-ylmethyl)-4-(trifluoromethyl)pyrimidine-5-carboxamide;2-(2,4-dichlorophenylamino)-N-((tetrahydro-2H-pyran-4-yl)methyl)-4-(trifluoromethyl)pyrimidine-5-carboxamide;2-(2,4-Dichlorophenylamino)-4-trifluoromethylpyrimidine-5-carboxylic acid [(tetrahydropyran-4-yl)methyl]amide;5-Pyrimidinecarboxamide, 2-[(2,4-dichlorophenyl)amino]-N-[(tetrahydro-2H-pyran-4-yl)methyl]-4-(trifluoromethyl)-
CBNumber:
CB32455643
Molecular Formula:
C18H17Cl2F3N4O2
Molecular Weight:
449.25
MDL Number:
MFCD11045840
MOL File:
666260-75-9.mol
MSDS File:
SDS
Last updated:2023-05-21 10:59:17
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GW 842166X Properties

storage temp. Store at -20°C
solubility DMF:20.0(Max Conc. mg/mL);44.52(Max Conc. mM)
DMF:PBS (pH 7.2) (1:3):0.25(Max Conc. mg/mL);0.56(Max Conc. mM)
DMSO:37.77(Max Conc. mg/mL);84.07(Max Conc. mM)
Ethanol:0.3(Max Conc. mg/mL);0.67(Max Conc. mM)
form Powder
FDA UNII VL1I6P2DZ8

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

GW 842166X price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 10010372 GW 842166X ≥98% 666260-75-9 1mg $22 2024-03-01 Buy
Cayman Chemical 10010372 GW 842166X ≥98% 666260-75-9 5mg $95 2024-03-01 Buy
Cayman Chemical 10010372 GW 842166X ≥98% 666260-75-9 10mg $168 2024-03-01 Buy
Cayman Chemical 10010372 GW 842166X ≥98% 666260-75-9 25mg $319 2024-03-01 Buy
TRC G931520 GW-842166X 666260-75-9 25mg $370 2021-12-16 Buy
Product number Packaging Price Buy
10010372 1mg $22 Buy
10010372 5mg $95 Buy
10010372 10mg $168 Buy
10010372 25mg $319 Buy
G931520 25mg $370 Buy

GW 842166X Chemical Properties,Uses,Production

Description

The peripheral cannabinoid (CB2) receptor is a G protein-coupled receptor (GPCR) that is localized predominantly in immune cells, monocytes, macrophages, and in several peripheral organs and binds the active component of cannabis, Δ9-tetrahydrocannabinol, as well as anandamide, an endogenous CB receptor ligand. GW 842166X is a peripheral cannabinoid (CB2) receptor agonist with ED50 values of 91 and 63 nM in rat and human, respectively. When administered orally to rats in the Freund’s complete adjuvant (FCA) model of inflammatory pain, GW 842166X is highly potent with an ED50 value of 0.1 mg/kg and full reversal of hyperalgesia at 0.3 mg/kg.

Uses

GW-842166X is pyrimidine ester based compound that is known as a highly selective CB2 receptor agonist for the treatment of inflammatory and neuropathic pain.

Definition

ChEBI: 5-pyrimidinecarboxamide, 2-[(2,4-dichlorophenyl)amino]-n-[(tetrahydro-2h-pyran-4-yl)methyl]-4-(trifluoromethyl)- is a dichlorobenzene.

GW 842166X Preparation Products And Raw materials

Raw materials

Preparation Products

GW 842166X Suppliers

Global( 95)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32480 60
Hubei xin bonus chemical co. LTD 		86-13657291602 linda@hubeijusheng.com CHINA 22968 58
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19553 58
career henan chemical co 		+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
Dideu Industries Group Limited 		+86-29-89586680 +86-15129568250 1026@dideu.com China 29067 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
TargetMol Chemicals Inc. 		+1-781-999-5354 support@targetmol.com United States 19973 58
Sichuan Biosynce Pharmatech Co., Ltd. 		+8619950309693 diane@biosynce.com China 4874 58
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 57511 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131981 58
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
Hubei xin bonus chemical co. LTD 		58
BOC Sciences 		58
career henan chemical co 		58
Dideu Industries Group Limited 		58
InvivoChem 		58
TargetMol Chemicals Inc. 		58
Sichuan Biosynce Pharmatech Co., Ltd. 		58
Aladdin Scientific 		58
Amadis Chemical Company Limited 		58

View Lastest Price from GW 842166X manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
GW842166X pictures 2020-01-13 GW842166X
666260-75-9
 US $1.00 / g 1g 95-99% 1ton Career Henan Chemical Co
  • GW842166X pictures
  • GW842166X
    666260-75-9
  • US $1.00 / g
  • 95-99%
  • Career Henan Chemical Co

666260-75-9(GW 842166X)Related Search:

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GW 842166X

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GW 842166X GW 842166 GW842166X/GW-842166X 2-(2,4-Dichlorophenylamino)-4-trifluoromethylpyrimidine-5-carboxylic acid [(tetrahydropyran-4-yl)methyl]amide 2-(2,4-dichlorophenylamino)-N-((tetrahydro-2H-pyran-4-yl)methyl)-4-(trifluoromethyl)pyrimidine-5-carboxamide 2-(2,4-dichloroanilino)-N-(oxan-4-ylmethyl)-4-(trifluoromethyl)pyrimidine-5-carboxamide GW842166X;GW 842166 CS-631 5-Pyrimidinecarboxamide, 2-[(2,4-dichlorophenyl)amino]-N-[(tetrahydro-2H-pyran-4-yl)methyl]-4-(trifluoromethyl)- GW 842166X USP/EP/BP 666260-75-9 C18H17Cl2F3N4O2 Inhibitors