ChemicalBook >> CAS DataBase List >>3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide
3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide
- CAS No.
- 781652-57-1
- Chemical Name:
- 3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide
- Synonyms
- CDPPB;mGluR5 Ligand, CDPPB;3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide;mGluR5 Ligand, CDPPB - CAS 781652-57-1 - Calbiochem;Benzamide, 3-cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)-
- CBNumber:
- CB32498277
- Molecular Formula:
- C23H16N4O
- Molecular Weight:
- 364.4
- MDL Number:
- MFCD12828752
- MOL File:
- 781652-57-1.mol
- MSDS File:
- SDS
Last updated:2023-06-30 15:45:59
| Melting point | 210-212°C |
|---|---|
| storage temp. | 2-8°C |
| solubility | DMSO: ≥5mg/mL at warmed to 60°C |
| form | powder |
| color | white to beige |
| FDA UNII | Y4F3R8YW3G |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22 | |||||||||
| WGK Germany | 3 | |||||||||
| NFPA 704 |
|
3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide price More Price(27)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML0235 | CDPPB ≥98% (HPLC) | 781652-57-1 | 5mg | $113 | 2024-03-01 | Buy |
| Sigma-Aldrich | 445865 | mGluR5 Ligand, CDPPB | 781652-57-1 | 1mg | $129 | 2022-05-15 | Buy |
| Sigma-Aldrich | SML0235 | CDPPB ≥98% (HPLC) | 781652-57-1 | 25mg | $579 | 2024-03-01 | Buy |
| Tocris | 3235 | CDPPB ≥98%(HPLC) | 781652-57-1 | 10 | $195 | 2021-12-16 | Buy |
| Tocris | 3235 | CDPPB ≥98%(HPLC) | 781652-57-1 | 50 | $818 | 2021-12-16 | Buy |
3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide Chemical Properties,Uses,Production
Uses
CDPPB may be used in mGluR5-mediated cell signaling studies.
Uses
3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide is a glutamate metabotropic (mGluR5) positive allosteric modulator, used in the treatment of Phelan-McDermid syndrome caused by 22qI3 deletion. Studies have shown that 3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide suppresses the incre ase of LDH release and caspase-3 activation induced by traumatic neuronal injury.
Biochem/physiol Actions
CDPPB is a glutamate metabotropic mGluR5 positive allosteric modulator.
storage
+4°C
3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 81)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| Hebei Duling International Trade Co. LTD | +8618032673083 | sales05@hbduling.cn | China | 15745 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24738 | 58 |
| Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd | +86-18341751992 +86-15382112998 | 757984502@qq.com | China | 892 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| Shanghai Ennopharm Co., Ltd. | +86 (21) 6435-5022 | China | 4271 | 65 |
781652-57-1(3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide)Related Search:
3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide
CDPPB
mGluR5 Ligand, CDPPB
mGluR5 Ligand, CDPPB - CAS 781652-57-1 - Calbiochem
Benzamide, 3-cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)-
781652-57-1