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(E/Z)-FK-506 26,28-Allylic Ester RearrangeMent IMpurity

(E/Z)-FK-506 26,28-Allylic Ester RearrangeMent IMpurity structure

CAS No.: 131944-48-4

Chemical Name:: (E/Z)-FK-506 26,28-Allylic Ester RearrangeMent IMpurity

Synonyms: Tacrolimus Impurity 2;Tacrolimus Rearrangement Lactone;Tacrolimus Impurity 21;Tacrolimus Impurity 29;Tacrolimus Impurity 13 （Positional Isomer ）;(E/Z)-FK-506 26,28-Allylic Ester Rearrangement Impurity;[3R-[3R*(1R*,3R*,4R*),4E,6S*,7S*,10R*,11E,14S*,16S*,17R*,18S*,20R*,21R*,28aS*]]-;[3R-[3R*(1R*,3R*,4R*),4E,6S*,7S*,10R*,11E,14S*,16S*,17R*,18S*,20R*,21R*,28aS*]]-7,8,10,13,14,15,16,17,18,19,20,21,26,27,28,28a-Hexadecahydro-7,21-dihydroxy-3-(4-hydroxy-3-methoxycyclohexyl)-16,18-dimethoxy-4,6,12,14,20-pentamethyl-10-(2-propenyl)-7,21-epo;17,21-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclopentacosine-1,9,22,23(6H,25H)-tetrone, 7,8,10,13,14,15,16,17,18,19,20,21,26,27,28,28a-hexadecahydro-7,21-dihydroxy-3-(4-hydroxy-3-methoxycyclohexyl)-16,18-dimethoxy-4,6,12,14,20-pentamethyl-10-(2-propenyl)-, [3R-[3R*(1R*,3R*,4R*),4E,6S*,7S*,10R*,11E,14S*,1...;17,21-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclopentacosine-1,9,22,23(6H,25H)-tetrone, 7,8,10,13,14,15,16,17,18,19,20,21,26,27,28,28a-hexadecahydro-7,21-dihydroxy-3-(4-hydroxy-3-methoxycyclohexyl)-16,18-dimethoxy-4,6,12,14,20-pentamethyl-10-(2-propenyl)-, [3R-[3R*(1R*,3R*,4R*),4E,6S*,7S*,10R*,11E,14S*,16S*,17R*,18S*,20R*,21R*,28aS*]]-

CBNumber:: CB32544268

Molecular Formula:: C44H69NO12

Molecular Weight:: 804.02

MDL Number:: MFCD28988714

MOL File:: 131944-48-4.mol

Last updated:2023-05-15 10:43:54

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(E/Z)-FK-506 26,28-Allylic Ester RearrangeMent IMpurity Properties

Melting point	115-120°C
Boiling point	879.7±75.0 °C(Predicted)
Density	1.19±0.1 g/cm3(Predicted)
storage temp.	-20°C Freezer
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Solid
pka	9.98±0.70(Predicted)
color	White to Pale Yellow
FDA UNII	Y8RY7CLE8L

(E/Z)-FK-506 26,28-Allylic Ester RearrangeMent IMpurity price More Price(7)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	F370020	(E/Z)-FK-50626,28-AllylicEsterRearrangementImpurity	131944-48-4	10mg	$90	2021-12-16	Buy
TRC	F370020	(E/Z)-FK-50626,28-AllylicEsterRearrangementImpurity	131944-48-4	25mg	$180	2021-12-16	Buy
Biosynth Carbosynth	IF23294	(E/Z)-FK-506 26,28-allylic ester rearrangement impurity	131944-48-4	1mg	$180	2021-12-16	Buy
Biosynth Carbosynth	IF23294	(E/Z)-FK-506 26,28-allylic ester rearrangement impurity	131944-48-4	2mg	$280	2021-12-16	Buy
Biosynth Carbosynth	IF23294	(E/Z)-FK-506 26,28-allylic ester rearrangement impurity	131944-48-4	5mg	$550	2021-12-16	Buy

Product number	Packaging	Price	Buy
F370020	10mg	$90	Buy
F370020	25mg	$180	Buy
IF23294	1mg	$180	Buy
IF23294	2mg	$280	Buy
IF23294	5mg	$550	Buy

(E/Z)-FK-506 26,28-Allylic Ester RearrangeMent IMpurity Chemical Properties,Uses,Production

Chemical Properties

White to Pale Yellow Solid

Uses

FK-506 (F370000) impurity. A new macrolite of thermal rearrangement of the immunosuppressant FK-506.

(E/Z)-FK-506 26,28-Allylic Ester RearrangeMent IMpurity Preparation Products And Raw materials

Raw materials

Preparation Products

(E/Z)-FK-506 26,28-Allylic Ester RearrangeMent IMpurity Suppliers

Global( 52)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
sgtlifesciences pvt ltd	+8617013299288	dj@sgtlifesciences.com	China	12382	58
China National Standard Pharmaceutical Corporation Limited	+8615391658522	overseasales@yongstandards.com	China	11927	58
Scinova Biotech(Guangzhou) Co., Ltd.	13268215580	scinova_sales@163.com	China	7026	58
Hubei Xinyang Medical Technology Co., Ltd	15347293736 15347293736	2853117764@qq.com	China	8854	58
Nanning Saifir Biotechnology Co., Ltd.	18877121284	1309367106@qq.com	China	296	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	94838	76
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32344	50
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	14059	65
Shanghai TaoSu Biochemical Technology Co., Ltd.	021-33632979	info@tsbiochem.com	China	8073	58

Supplier	Advantage
Hubei Jusheng Technology Co.,Ltd.	58
sgtlifesciences pvt ltd	58
China National Standard Pharmaceutical Corporation Limited	58
Scinova Biotech(Guangzhou) Co., Ltd.	58
Hubei Xinyang Medical Technology Co., Ltd	58
Nanning Saifir Biotechnology Co., Ltd.	58
J & K SCIENTIFIC LTD.	76
Chemsky（shanghai）International Co.,Ltd.	50
BOC Sciences	65
Shanghai TaoSu Biochemical Technology Co., Ltd.	58

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[3R-[3R*(1R*,3R*,4R*),4E,6S*,7S*,10R*,11E,14S*,16S*,17R*,18S*,20R*,21R*,28aS*]]- Tacrolimus Impurity 13 （Positional Isomer ） 17,21-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclopentacosine-1,9,22,23(6H,25H)-tetrone, 7,8,10,13,14,15,16,17,18,19,20,21,26,27,28,28a-hexadecahydro-7,21-dihydroxy-3-(4-hydroxy-3-methoxycyclohexyl)-16,18-dimethoxy-4,6,12,14,20-pentamethyl-10-(2-propenyl)-, [3R-[3R*(1R*,3R*,4R*),4E,6S*,7S*,10R*,11E,14S*,1... [3R-[3R*(1R*,3R*,4R*),4E,6S*,7S*,10R*,11E,14S*,16S*,17R*,18S*,20R*,21R*,28aS*]]-7,8,10,13,14,15,16,17,18,19,20,21,26,27,28,28a-Hexadecahydro-7,21-dihydroxy-3-(4-hydroxy-3-methoxycyclohexyl)-16,18-dimethoxy-4,6,12,14,20-pentamethyl-10-(2-propenyl)-7,21-epo Tacrolimus Impurity 21 Tacrolimus Impurity 2 Tacrolimus Rearrangement Lactone 17,21-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclopentacosine-1,9,22,23(6H,25H)-tetrone, 7,8,10,13,14,15,16,17,18,19,20,21,26,27,28,28a-hexadecahydro-7,21-dihydroxy-3-(4-hydroxy-3-methoxycyclohexyl)-16,18-dimethoxy-4,6,12,14,20-pentamethyl-10-(2-propenyl)-, [3R-[3R*(1R*,3R*,4R*),4E,6S*,7S*,10R*,11E,14S*,16S*,17R*,18S*,20R*,21R*,28aS*]]- Tacrolimus Impurity 29 (E/Z)-FK-506 26,28-Allylic Ester Rearrangement Impurity 131944-48-4 Chiral Reagents, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals Chiral Reagents Impurities Intermediates & Fine Chemicals Pharmaceuticals