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Z-NH-5(ethylene glycol)-acetic acid

CAS No.
1449390-66-2
Chemical Name:
Z-NH-5(ethylene glycol)-acetic acid
Synonyms
CbzNH-P5-CH2CO2H;Z-NH-PEG5-CH2COOH;CBZ-NH-PEG5-CH2COOH;CBZ-NH-PEG5-acetic acid;Z-NH-5(ethylene glycol)-acetic acid;5,8,11,14,17-Pentaoxa-2-azanonadecanedioic acid, 1-(phenylmethyl) ester;CbzNH-PEG5-CH2COOH/5,8,11,14,17-Pentaoxa-2-azanonadecanedioic acid, 1-(phenylmethyl) ester;inhibit,PROTAC Linkers,Cbz-NH-PEG-5-CH2COOH,Inhibitor,Cbz NH PEG5 CH2COOH,CbzNHPEG5CH2COOH
CBNumber:
CB32547012
Molecular Formula:
C20H31NO9
Molecular Weight:
429.46
MDL Number:
MFCD31656969
MOL File:
1449390-66-2.mol
Last updated:2023-02-23 14:24:01

Z-NH-5(ethylene glycol)-acetic acid price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Activate Scientific AS107905 CbzNH-PEG5-CH2COOH 97% 1449390-66-2 250mg $283 2021-12-16 Buy
chempep 280303 Z-NH-PEG5-CH2COOH >=95% 1449390-66-2 1g $433 2021-12-16 Buy
ChemPep 280303 Z-NH-PEG5-CH2COOH 1449390-66-2 5g $1083 2021-12-16 Buy
purepeg 4322905 CBZ-NH-PEG5-CH2COOH min.97% 1449390-66-2 1g $450 2021-12-16 Buy
Acrotein B-1093 CbzNH-PEG5-CH2COOH 97% 1449390-66-2 1g $412.5 2021-12-16 Buy
Product number Packaging Price Buy
AS107905 250mg $283 Buy
280303 1g $433 Buy
280303 5g $1083 Buy
4322905 1g $450 Buy
B-1093 1g $412.5 Buy

Z-NH-5(ethylene glycol)-acetic acid Chemical Properties,Uses,Production

Biological Activity

Cbz-NH-PEG5-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Z-NH-5(ethylene glycol)-acetic acid Preparation Products And Raw materials

Raw materials

Preparation Products

Z-NH-5(ethylene glycol)-acetic acid Suppliers

Global( 19)Suppliers
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9i LLC
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SHANGHAI T&W PHARMACEUTICAL CO., LTD.
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TargetMol Chemicals Inc.
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ChemPep, Inc. +1 (888) 615-9178 / (561) 791-8787 service@chempep.com United States 2138 57
T&W GROUP 021-61551611 13296011611 contact@trustwe.com China 9900 58
Tongling HengYou Biotechnology Co., Ltd. 021-50426030 13856289449 2630597085@qq.com China 1889 55
Amatek Scientific Co. Ltd. 0512-56316828 info@amateksci.com China 28822 58
Hangzhou HanLai Biochemical Technology Co., Ltd. 0571-86101219 13675881727 sales@leobiochem.com China 433 58
Nanjing Ze Feng biological medicine technology Co., Ltd. 18851912129; 18851912129 1670471576@qq.com China 1065 58
Suzhou Derivative Biotechnology Co., Ltd. 13915541704 2436368162@qq.com China 304 58
Z-NH-5(ethylene glycol)-acetic acid Z-NH-PEG5-CH2COOH CBZ-NH-PEG5-acetic acid CBZ-NH-PEG5-CH2COOH 5,8,11,14,17-Pentaoxa-2-azanonadecanedioic acid, 1-(phenylmethyl) ester CbzNH-P5-CH2CO2H inhibit,PROTAC Linkers,Cbz-NH-PEG-5-CH2COOH,Inhibitor,Cbz NH PEG5 CH2COOH,CbzNHPEG5CH2COOH CbzNH-PEG5-CH2COOH/5,8,11,14,17-Pentaoxa-2-azanonadecanedioic acid, 1-(phenylmethyl) ester 1449390-66-2 PEGylated Amino Acid