Erteberel (LY500307)
- CAS No.
- 533884-09-2
- Chemical Name:
- Erteberel (LY500307)
- Synonyms
- Erteberel;Phenchlobenpyrrone;CS-897;SERBA-1;LY500307;LY500307 (Erteberel);Erteberel (LY500307);Erteberel LY500307 LY-500307;Erteberel (LY500307) USP/EP/BP;Inhibitor,LY-500307,inhibit,Estrogen Receptor/ERR,Erteberel,LY 500307
- CBNumber:
- CB32561485
- Molecular Formula:
- C18H18O3
- Molecular Weight:
- 282.33
- MDL Number:
- MFCD22495234
- MOL File:
- 533884-09-2.mol
- MSDS File:
- SDS
| Boiling point | 485.2±45.0 °C(Predicted) |
|---|---|
| Density | 1.268 |
| storage temp. | Store at -20°C |
| solubility | insoluble in H2O; ≥14.1 mg/mL in DMSO; ≥48.3 mg/mL in EtOH |
| form | solid |
| pka | 9.79±0.30(Predicted) |
| FDA UNII | 2ZUL6758TZ |
Erteberel (LY500307) price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 22130 | Erteberel ≥98% | 533884-09-2 | 1mg | $72 | 2024-03-01 | Buy |
| Cayman Chemical | 22130 | Erteberel ≥98% | 533884-09-2 | 5mg | $301 | 2024-03-01 | Buy |
| Cayman Chemical | 22130 | Erteberel ≥98% | 533884-09-2 | 10mg | $530 | 2024-03-01 | Buy |
| TRC | E649895 | Erteberel | 533884-09-2 | 1mg | $195 | 2021-12-16 | Buy |
| ApexBio Technology | B1518 | Erteberel(LY500307) | 533884-09-2 | 5mg | $350 | 2021-12-16 | Buy |
Erteberel (LY500307) Chemical Properties,Uses,Production
Uses
Erteberel is a highly selective estrogen receptor β (ERβ) agonist.
Biological Activity
erteberel (ly500307) is a potent and selective erβ (estrogen receptor beta) agonist (ec50 = 0.66 nm). [1]estrogen receptors are nuclear hormone receptors that act as a ligand-activated transcription factor. it regulates gene expression, cell proliferation and differentiation in target tissues and involved in breast cancer, endometrial cancer and osteoporosis etc. [1]in transcription assay of cotransfected human prostate cancer cell line, erteberel showed potency (ec50 = 0.66 nm), selectivity (32-fold) and full agonist function (>90% relative efficacy) to erβ than to erα. [1]in mouse model, prostate wet weight of cd-1 mice were measured following oral daily doses of erteberel for 7 days. results showed reduction on prostate weight in a dose-dependent manner (0.01 mg/kg – 0.05 mg/kg), and no effect on testes/seminal vesicle weight and androgens testosterone/dihydrotestosterone circulating level. [1]
References
[1] norman bh, dodge ja, richardson ti, borromeo ps, lugar cw, jones sa, chen k, wang y, durst gl, barr rj, montrose-rafizadeh c, osborne he, amos rm, guo s, boodhoo a, krishnan v. benzopyrans are selective estrogen receptor beta agonists with novel activity in models of benign prostatic hyperplasia. j med chem. 2006 oct 19;49(21):6155-7.
Erteberel (LY500307) Preparation Products And Raw materials
Raw materials
Preparation Products
Erteberel (LY500307) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 7038 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 47465 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 29627 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| ZHEJIANG JIUZHOU CHEM CO., LTD | +86-0576225566889 +86-13454675544 | admin@jiuzhou-chem.com；jamie@jiuzhou-chem.com；alice@jiuzhou-chem.com | China | 20000 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
View Lastest Price from Erteberel (LY500307) manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-03-29 | Erteberel (LY500307)
533884-09-2
|
US $32.00-1.30 / kg | 1kg | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2020-01-14 | Erteberel (LY500307)
533884-09-2
|
US $1.00 / g | 1g | 99% | 200kg | Career Henan Chemical Co | |
|
|
2020-01-14 | Erteberel (LY500307)
533884-09-2
|
US $1.00 / g | 1g | 99% | 200kg | Career Henan Chemical Co |
-
- Erteberel (LY500307)
533884-09-2
- US $32.00-1.30 / kg
- 99%
- Henan Fengda Chemical Co., Ltd
-
- Erteberel (LY500307)
533884-09-2
- US $1.00 / g
- 99%
- Career Henan Chemical Co
-
- Erteberel (LY500307)
533884-09-2
- US $1.00 / g
- 99%
- Career Henan Chemical Co