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Isosorbide 5-mononitrate

Isosorbide 5-mononitrate
Isosorbide 5-mononitrate structure
CAS No.
16051-77-7
Chemical Name:
Isosorbide 5-mononitrate
Synonyms
ELAN;Ismo;Momt;ISMN;IMDUR;5-ismn;Coronu;ELANTAN;IS-5-MN;ahr4698
CBNumber:
CB3256697
Molecular Formula:
C6H9NO6
Formula Weight:
191.14
MOL File:
16051-77-7.mol

Isosorbide 5-mononitrate Properties

Melting point:
88-93 °C
alpha 
170 º (c=1, EtOH)
Boiling point:
326.86°C (rough estimate)
Density 
1.5784 (rough estimate)
refractive index 
145 ° (C=5, H2O)
storage temp. 
-20°C Freezer
solubility 
Undiluted isosorbide mononitrate is freely soluble in water, in acetone, in ethanol (96 per cent) and in methylene chloride. The solubility of the diluted product depends on the diluent and its concentration.
pka
13.09±0.40(Predicted)
Water Solubility 
soluble
Merck 
5225
InChIKey
YWXYYJSYQOXTPL-SLPGGIOYSA-N
CAS DataBase Reference
16051-77-7(CAS DataBase Reference)
FDA UNII
LX1OH63030
EPA Substance Registry System
D-Glucitol, 1,4:3,6-dianhydro-, 5-nitrate (16051-77-7)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS02,GHS07
Signal word  Danger
Hazard statements  H302-H228
Precautionary statements  P240-P241-P280-P301+P312a-P501a-P210-P370+P378
Hazard Codes  Xi-F,Xi,F
Risk Statements  36/37/38-11
Safety Statements  37/39-16-15
RIDADR  3251
RTECS  LZ4386500
HazardClass  1.1A
HS Code  2932999000
Toxicity LD50 oral in rat: 2010mg/kg

Isosorbide 5-mononitrate price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich I0775010 Isosorbide mononitrate European Pharmacopoeia (EP) Reference Standard 16051-77-7 i0775010 $173 2019-12-02 Buy
Alfa Aesar J63674 Isosorbide mononitrate, 98+% 16051-77-7 5g $194 2021-03-22 Buy
Alfa Aesar J63674 Isosorbide mononitrate, 98+% 16051-77-7 10g $309 2021-03-22 Buy
Alfa Aesar J63674 Isosorbide mononitrate, 98+% 16051-77-7 25g $644 2021-03-22 Buy

Isosorbide 5-mononitrate Chemical Properties,Uses,Production

Chemical Properties

white to light yellow crystal powde

Uses

antidepressant, 5HT reuptake inhibitor

Uses

A metabolite of Isosorbide Dinitrate. Used as an antianginal

brand name

Imdur (Schering-Plough); Ismo (Dr. Reddy’s); Monoket (Schwarz Pharma) .

General Description

Isosorbide 5-mononitrate is a crystalline solid. Isosorbide 5-mononitrate is very flammable and may be toxic by ingestion.

Air & Water Reactions

Highly flammable.

Reactivity Profile

The dinitrate, a heart drug, can detonate when dry, but is non explosive with 30% of water [J. Haz.. Mater., 1992, 32(1), 87]. The mononitrate would be expected to be less reactive.

Health Hazard

Fire may produce irritating and/or toxic gases. Contact may cause burns to skin and eyes. Contact with molten substance may cause severe burns to skin and eyes. Runoff from fire control may cause pollution.

Fire Hazard

Flammable/combustible material. May be ignited by friction, heat, sparks or flames. Some may burn rapidly with flare burning effect. Powders, dusts, shavings, borings, turnings or cuttings may explode or burn with explosive violence. Substance may be transported in a molten form at a temperature that may be above its flash point. May re-ignite after fire is extinguished.

Isosorbide 5-mononitrate Preparation Products And Raw materials

Raw materials

Preparation Products


Isosorbide 5-mononitrate Suppliers

Global( 274)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21648 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22610 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070
product@chemlin.com.cn CHINA 3013 60
Jinan Shengqi pharmaceutical Co,Ltd
86+18663751872
christine@shengqipharm.com CHINA 481 58
Casorganics US Corp
+17326109938
sales@casorganics.com CHINA 175 58
QUALITY CONTROL CHEMICALS INC.
(323) 306-3136
(626) 453-0409 orders@qcchemical.com United States 8406 58
Hebei Guanlang Biotechnology Co., Ltd.
+8619930503282 whatapp+8619930503282
86-0311-66562153 sales3@crovellbio.com CHINA 2288 58
Chongqing Chemdad Co.,Ltd
+86-19923101450
sales@chemdad.com CHINA 4000 58
Xiamen AmoyChem Co., Ltd
+86 592-605 1114
sales@amoychem.com CHINA 6369 58
HubeiwidelychemicaltechnologyCo.,Ltd
18627774460
faith@widelychemical.com CHINA 743 58

View Lastest Price from Isosorbide 5-mononitrate manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2020-05-11 Isosorbide 5-mononitrate
16051-77-7
US $0.00-0.00 / KG 1KG 99.0% 500 MT Shaanxi Dideu Medichem Co. Ltd
2019-12-31 Isosorbide 5-mononitrate
16051-77-7
US $1.00 / KG 1KG 99% 10000KGS Career Henan Chemical Co

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