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JNJ 31020028

JNJ 31020028 structure

CAS No.: 1094873-14-9

Chemical Name:: JNJ 31020028

Synonyms: CS-1745;JNJ 31020028;JNJ31020028, >98%;JNJ-31020028?, >98%;JNJ-31020028;JNJ 31020028;1-Piperazineacetamide, N,N-diethyl-4-[2-fluoro-4-[[2-(3-pyridinyl)benzoyl]amino]phenyl]-α-phenyl-;N,N-Diethyl-4-[2-fluoro-4-[[2-(3-pyridinyl)benzoyl]amino]phenyl]-alpha-phenyl-1-piperazineacetamide;N-(4-(4-(2-(diethylamino)-2-oxo-1-phenylethyl)piperazin-1-yl)-3-fluorophenyl)-2-(pyridin-3-yl)benzamide;4-[1-(BENZENESULFONYL)-4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRROLO[2,3-B]PYRIDIN-2-YL]BENZALDEHYDE;hypothalamus,JNJ-31020028,anxiety,microdialysis,depression,JNJ31020028,norepinephrine,NPY receptor,Neuropeptide Y Receptor,Inhibitor,stress-induced anorexia,inhibit

CBNumber:: CB32627994

Molecular Formula:: C34H36FN5O2

Molecular Weight:: 565.68

MDL Number:: MFCD18782744

MOL File:: 1094873-14-9.mol

MSDS File:: SDS

Last updated:2023-09-20 16:43:00

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JNJ 31020028 Properties

Boiling point	677.5±55.0 °C(Predicted)
Density	1.228±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO : 21.5 mg/mL (38.01 mM; Need ultrasonic and warming)
form	Powder
pka	12.14±0.70(Predicted)
FDA UNII	73F8XED6YP

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

NFPA 704

	0
2		0

JNJ 31020028 price More Price(25)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	18407	JNJ-31020028 ≥95%	1094873-14-9	1mg	$68	2024-03-01	Buy
Cayman Chemical	18407	JNJ-31020028 ≥95%	1094873-14-9	5mg	$152	2024-03-01	Buy
Cayman Chemical	18407	JNJ-31020028 ≥95%	1094873-14-9	10mg	$268	2024-03-01	Buy
Cayman Chemical	18407	JNJ-31020028 ≥95%	1094873-14-9	25mg	$586	2024-03-01	Buy
Usbiological	474118	JNJ-31020028	1094873-14-9	100mg	$1507	2021-12-16	Buy

Product number	Packaging	Price	Buy
18407	1mg	$68	Buy
18407	5mg	$152	Buy
18407	10mg	$268	Buy
18407	25mg	$586	Buy
474118	100mg	$1507	Buy

JNJ 31020028 Chemical Properties,Uses,Production

Description

JNJ-31020028 is a brain-permeable selective antagonist of the neuropeptide Y (NPY) receptor Y₂ (IC₅₀s = 8.51, 6.03, and 6.17 nM for human, rat, and mouse receptors, respectively) with over 100-fold selectivity for Y₂ over Y₁, Y₄, and Y₅ receptors. JNJ-31020028 inhibits calcium release induced by peptide YY in a functional assay in KAN-TS cells (pK_B = 8.04) and blocks NPY(13-36)-induced decreases in twitch contraction amplitude in isolated rat vas deferens (IC₅₀ = 7.94 nM). Administration of JNJ-31020028 to rats during abstinence (20 mg/kg per day, i.p.) reverses nicotine-induced social anxiety-like behavior and increases hippocampal Y₂ receptor mRNA levels. It reverses withdrawal-induced anxiety-like behavior in rats in the elevated plus maze following a single bolus dose of alcohol when administered at a dose of 15 mg/kg. In an olfactory bulbectomized rat model of depression, chronic JNJ-31020028 treatment (10 nmol per day, i.c.v.) decreases immobility time in the forced swim test but has no effect in control animals.

JNJ 31020028 Preparation Products And Raw materials

Raw materials

Preparation Products

JNJ 31020028 Suppliers

Global( 74)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6313	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	trendseenbio@gmail.com	China	11681	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8474	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+undefined18621343501	product@acmec-e.com	China	33349	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131981	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
TargetMol Chemicals Inc.	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	58
InvivoChem	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	58
Wuhan Topule Biopharmaceutical Co., Ltd	58
Shanghai Acmec Biochemical Technology Co., Ltd.	58
Aladdin Scientific	58
Amadis Chemical Company Limited	58

View Lastest Price from JNJ 31020028 manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2019-09-06	JNJ 31020028 1094873-14-9	US $1.00 / KG	1KG	95%~99%	per week 100kg	Career Henan Chemical Co

JNJ 31020028
1094873-14-9
US $1.00 / KG
95%~99%
Career Henan Chemical Co

JNJ 31020028 Spectrum

JNJ 31020028(1094873-14-9)¹HNMR

1094873-14-9(JNJ 31020028)Related Search:

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JNJ-7706621 JNJ 63533054 JNJ-26481585 N-(4-chloropyridin-3-yl)-4-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)Methyl)piperazine-1-carboxaMide JNJ-10229570

JNJ-632 2-(4-Chlorophenoxy)-2-methyl-N-[5-[(methylsulfonyl)amino]tricyclo[3.3.1.13,7]dec-2-yl]-propanamide

1of3

JNJ 31020028 N-(4-(4-(2-(diethylamino)-2-oxo-1-phenylethyl)piperazin-1-yl)-3-fluorophenyl)-2-(pyridin-3-yl)benzamide N,N-Diethyl-4-[2-fluoro-4-[[2-(3-pyridinyl)benzoyl]amino]phenyl]-alpha-phenyl-1-piperazineacetamide 4-[1-(BENZENESULFONYL)-4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRROLO[2,3-B]PYRIDIN-2-YL]BENZALDEHYDE JNJ31020028, >98% JNJ-31020028?, >98% CS-1745 JNJ-31020028;JNJ 31020028 1-Piperazineacetamide, N,N-diethyl-4-[2-fluoro-4-[[2-(3-pyridinyl)benzoyl]amino]phenyl]-α-phenyl- hypothalamus,JNJ-31020028,anxiety,microdialysis,depression,JNJ31020028,norepinephrine,NPY receptor,Neuropeptide Y Receptor,Inhibitor,stress-induced anorexia,inhibit 1094873-14-9 C34H36FN5O2 Inhibitors