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trans/cis Resveratrol-D4

CAS No.
1089051-56-8
Chemical Name:
trans/cis Resveratrol-D4
Synonyms
trans/cis Resveratrol-D4;5-[(E)-2-(2,3,5,6-tetradeuterio-4-hydroxyphenyl)ethenyl]benzene-1,3-diol;Resveratrol D4Q: What is Resveratrol D4 Q: What is the CAS Number of Resveratrol D4 Q: What is the storage condition of Resveratrol D4 Q: What are the applications of Resveratrol D4
CBNumber:
CB32647480
Molecular Formula:
C14H8D4O3
Molecular Weight:
232.267927112
MDL Number:
MOL File:
1089051-56-8.mol
Last updated:2023-06-08 09:03:09

trans/cis Resveratrol-D4 Properties

storage temp. Store at -20°C
solubility DMF: >100 mg/ml,DMSO: >50mg/ml,Ethanol: >50mg/ml,PBS (pH 7.2): <100 μg/ml

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS02,GHS08
Signal word  Danger
Hazard statements  H225-H350
Precautionary statements  P201-P202-P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P308+P313-P370+P378-P403+P235-P405-P501
NFPA 704
3
0 0

trans/cis Resveratrol-D4 price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 13130 trans-Resveratrol-d4 ≥99% deuterated forms (d1-d4) 1089051-56-8 100μg $49 2024-03-01 Buy
Cayman Chemical 13130 trans-Resveratrol-d4 ≥99% deuterated forms (d1-d4) 1089051-56-8 250μg $115 2024-03-01 Buy
Cayman Chemical 13130 trans-Resveratrol-d4 ≥99% deuterated forms (d1-d4) 1089051-56-8 500μg $216 2024-03-01 Buy
Cayman Chemical 13130 trans-Resveratrol-d4 1089051-56-8 1000μg $380 2024-03-01 Buy
TRC R150001 Resveratrol-d4 1089051-56-8 10mg $475 2021-12-16 Buy
Product number Packaging Price Buy
13130 100μg $49 Buy
13130 250μg $115 Buy
13130 500μg $216 Buy
13130 1000μg $380 Buy
R150001 10mg $475 Buy

trans/cis Resveratrol-D4 Chemical Properties,Uses,Production

Description

trans-Resveratrol-d4 is intended for use as an internal standard for the quantification of trans-resveratrol by GC- or LC-MS. trans-Resveratrol is a polyphenolic phytoalexin found in a variety of plants, including grapes, that has anti-inflammatory, antioxidant, and anticancer activities. It inhibits the cyclooxygenase and hydroperoxidase activities of COX-1 (EC50s = 15 and 3.7 μM, respectively), but not COX-2 (EC50s = >100 μM and 85 μM, respectively). trans-Resveratrol (3 and 8 mg/kg) inhibits carrageenan-induced paw edema in mice. It inhibits free radical formation in HL-60 human promyelocytic leukemia cells induced by phorbol 12-myristate 13-acetate (TPA; ; EC50 = 27 μM). trans-Resveratrol (1-25 μmol) reduces both the incidence and number of tumors in a two-stage mouse model of skin cancer induced by TPA and 7,12-dimethyl-benz[a]anthracene (DMBA). trans-Resveratrol (200 μM) also activates sirtuin 1 (SIRT1) by 8-fold in vitro and inhibits a variety of targets including ERK1, JNK1, Src, PKCα, aromatase/CYP19, and DNA polymerases α and δ (IC50s = 37, 50, 20, <10, 25, 3.3, and 5 μM, respectively) in vitro and/or ex vivo. It prolongs lifespan in model organisms including C. elegans, D. melanogaster, and mice.

Uses

Resveratrol-d4 is labelled Resveratrol (R150000) which is a minor constituent of wine, correlated with serum lipid reduction and inhibition of platelet aggregation. Resveratrol is a specific inhibitor of COX-1, and it also inhibits the hydroperoxidase activity of COX-1. It has been shown to inhibit events associated with tumor initiation, promotion and progression.

trans/cis Resveratrol-D4 Preparation Products And Raw materials

Raw materials

Preparation Products

trans/cis Resveratrol-D4 Suppliers

Global( 12)Suppliers
Supplier Tel Email Country ProdList Advantage
Clearsynth Labs Limited +91-22-26355700 info@clearsynth.com India 9685 58
Hangzhou Synstar pharmaceutical Technology CO.,Ltd 0571-85361029 synstar518@163.com China 1991 58
Guangzhou Dreampharm Biotechnology Co., Ltd. 17825480238 3008233717@qq.com China 9844 12
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Hubei Xinyang Medical Technology Co., Ltd 15347293736 15347293736 2853117764@qq.com China 9058 58
Energy Chemical 021-58432009 400-005-6266 marketing1@energy-chemical.com China 44894 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8740 58
Nanjing Shizhou Biology Technology Co.,Ltd 17301488900 judy.xia@synzest.com China 13698 58
trans/cis Resveratrol-D4 Resveratrol D4Q: What is Resveratrol D4 Q: What is the CAS Number of Resveratrol D4 Q: What is the storage condition of Resveratrol D4 Q: What are the applications of Resveratrol D4 5-[(E)-2-(2,3,5,6-tetradeuterio-4-hydroxyphenyl)ethenyl]benzene-1,3-diol 1089051-56-8 C14H8D4O3