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AZD 8329
- CAS No.
- 1048668-70-7
- Chemical Name:
- AZD 8329
- Synonyms
- AZD 8329;AZD 8329 (AZD8329);XWBXJBSVYVJAMZ-UHFFFAOYSA-N;4-(4-(Adamantan-2-ylcarbamoyl)-5-(tert-butyl)-1H-pyrazol-1-yl)benzoic acid;Benzoic acid, 4-[5-(1,1-dimethylethyl)-4-[(tricyclo[3.3.1.13,7]dec-2-ylamino)carbonyl]-1H-pyrazol-1-yl]-
- CBNumber:
- CB32668610
- Molecular Formula:
- C25H31N3O3
- Molecular Weight:
- 421.53
- MDL Number:
- MOL File:
- 1048668-70-7.mol
Last updated:2025-07-16 20:18:59
| Boiling point | 620.5±50.0 °C(Predicted) |
|---|---|
| Density | 1.37±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO: 62.5 mg/mL (148.27 mM) |
| form | Solid |
| pka | 3.77±0.10(Predicted) |
| color | White to off-white |
| FDA UNII | 5B38CV1212 |
AZD 8329 Chemical Properties,Uses,Production
Uses
AZD8329 is a potent 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor with an IC50 of 9 nM for human 11β-HSD1, displays excellent selectivity versus 11β-HSD2, 17β-HSD1 and 17β-HSD3[1].
References
[1] Scott JS, et al. Novel acidic 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor with reduced acyl glucuronide liability: the discovery of 4-[4-(2-adamantylcarbamoyl)-5-tert-butyl-pyrazol-1-yl]benzoic acid (AZD8329). J Med Chem. 2012 Nov 26;55(22):10136-47. DOI:10.1021/jm301252n
AZD 8329 Preparation Products And Raw materials
Raw materials
Preparation Products
AZD 8329 Suppliers
Global( 21)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 32375 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38832 | 58 | |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 12952 | 65 |
| Bide Pharmatech Ltd. | 400-164-7117 13681763483 | product02@bidepharm.com | China | 42446 | 60 |
| Shanghai Chaolan Chemical Technology Center | 021-QQ：65489617 15618227136 | Sales@ATKchemical.com | China | 9368 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11218 | 58 |
| Shanghai hongqu biomedical technology co. LTD | 88888888888 | hongquchem@qq.com | China | 5132 | 58 |
| Suzhou Chenrui Biotechnology Co. LTD | 17625585511 | 1580084073@qq.com | China | 878 | 58 |
View Lastest Price from AZD 8329 manufacturers
AZD 8329
XWBXJBSVYVJAMZ-UHFFFAOYSA-N
AZD 8329
(AZD8329)
Benzoic acid, 4-[5-(1,1-dimethylethyl)-4-[(tricyclo[3.3.1.13,7]dec-2-ylamino)carbonyl]-1H-pyrazol-1-yl]-
4-(4-(Adamantan-2-ylcarbamoyl)-5-(tert-butyl)-1H-pyrazol-1-yl)benzoic acid
1048668-70-7