ChemicalBook >> CAS DataBase List >>4-Methoxy-3-methylphenyl piperidin-1-yl sulphone, 2-Methyl-4-[(piperidin-1-yl)sulphonyl]anisole
4-Methoxy-3-methylphenyl piperidin-1-yl sulphone, 2-Methyl-4-[(piperidin-1-yl)sulphonyl]anisole
![4-Methoxy-3-methylphenyl piperidin-1-yl sulphone, 2-Methyl-4-[(piperidin-1-yl)sulphonyl]anisole Structure](CAS/GIF/457961-34-1.gif)
- CAS No.
- 457961-34-1
- Chemical Name:
- 4-Methoxy-3-methylphenyl piperidin-1-yl sulphone, 2-Methyl-4-[(piperidin-1-yl)sulphonyl]anisole
- Synonyms
- Cy1001;AA92593;AA92593 >=98% (HPLC);1-(4-Methoxy-3-methyl-benzenesulfonyl)-piperidine;1-[(4-Methoxy-3-methylphenyl)sulphonyl]piperidine;Piperidine, 1-[(4-methoxy-3-methylphenyl)sulfonyl]-;Per1,AA-92593,Melanopsin,α-MSH,AA92593,inhibit,Inhibitor,OPN4,AA 92593,Melanoma,CHO;4-Methoxy-3-methylphenyl piperidin-1-yl sulphone, 2-Methyl-4-[(piperidin-1-yl)sulphonyl]anisole
- CBNumber:
- CB32696509
- Molecular Formula:
- C13H19NO3S
- Molecular Weight:
- 269.36
- MDL Number:
- MOL File:
- 457961-34-1.mol
- MSDS File:
- SDS
Last updated:2023-06-08 09:03:05
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36-37-38 | |||||||||
| Safety Statements | 26 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 2933998090 | |||||||||
| NFPA 704 |
|
4-Methoxy-3-methylphenyl piperidin-1-yl sulphone, 2-Methyl-4-[(piperidin-1-yl)sulphonyl]anisole price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML0865 | AA92593 ≥98% (HPLC) | 457961-34-1 | 5mg | $125 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML0865 | AA92593 ≥98% (HPLC) | 457961-34-1 | 25mg | $478 | 2024-03-01 | Buy |
| Sigma-Aldrich | 5.09267 | Opn4 Antagonist - CAS 457961-34-1 - Calbiochem Prevents melanopsin/Opn4 photoactivation in a reversible manner. Inhibits cellular phototransduction mediated by human Opn4 (IC?? = 665 nM; using CHO transfectants). | 457961-34-1 | 10MG | $148 | 2024-03-01 | Buy |
| AK Scientific | SYN5091 | AA92593 | 457961-34-1 | 100mg | $850 | 2021-12-16 | Buy |
| DC Chemicals | DC43509 | AA92593 >98% | 457961-34-1 | 100mg | $400 | 2021-12-16 | Buy |
4-Methoxy-3-methylphenyl piperidin-1-yl sulphone, 2-Methyl-4-[(piperidin-1-yl)sulphonyl]anisole Chemical Properties,Uses,Production
Uses
AA92593 has been used as a selective melanopsin inhibitor.
Biochem/physiol Actions
AA92593 is an opsinamide, a potent antagonist of melanopsin-mediated phototransduction with an IC50 of 665 nM in a Ca2+ flux assay in CHO cells expressing melanopsin (Opn4) and selectivity > 10 μM at 74 common biological targets. AA41612 is believed to act by competing for binding to melanopsin. AA41612 inhibited mouse pupillary light reflex and light aversion in vivo. AA92593 and similar compounds might be useful in alleviating the photophobia associated with migraine.
4-Methoxy-3-methylphenyl piperidin-1-yl sulphone, 2-Methyl-4-[(piperidin-1-yl)sulphonyl]anisole Preparation Products And Raw materials
Raw materials
Preparation Products
4-Methoxy-3-methylphenyl piperidin-1-yl sulphone, 2-Methyl-4-[(piperidin-1-yl)sulphonyl]anisole Suppliers
Global( 35)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| Nanjing Doge Biomedical Technology Co., Ltd | +86-25-58227606 +86-15305155328 | sales@dogechemical.com | China | 4128 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
| Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd | +86-18341751992 +86-15382112998 | 757984502@qq.com | China | 892 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
457961-34-1(4-Methoxy-3-methylphenyl piperidin-1-yl sulphone, 2-Methyl-4-[(piperidin-1-yl)sulphonyl]anisole)Related Search:
1-[(4-Methoxy-3-methylphenyl)sulphonyl]piperidine
4-Methoxy-3-methylphenyl piperidin-1-yl sulphone, 2-Methyl-4-[(piperidin-1-yl)sulphonyl]anisole
1-(4-Methoxy-3-methyl-benzenesulfonyl)-piperidine
AA92593
Cy1001
Piperidine, 1-[(4-methoxy-3-methylphenyl)sulfonyl]-
AA92593 >=98% (HPLC)
Per1,AA-92593,Melanopsin,α-MSH,AA92593,inhibit,Inhibitor,OPN4,AA 92593,Melanoma,CHO
457961-34-1