2'-DEOXY-L-CYTIDINE
- CAS No.
- 40093-94-5
- Chemical Name:
- 2'-DEOXY-L-CYTIDINE
- Synonyms
- L-dC;NV 02C;NV-02C;Torcitabine;L-Deoxycytidine;L-2'-deoxycytidine;L-2’-deoxycytidine;2'-DEOXY-L-CYTIDINE;2'-DEOXY-L-CYTIDINE;BETA-L-2'-DEOXYCYTIDINE
- CBNumber:
- CB3272943
- Molecular Formula:
- C9H13N3O4
- Molecular Weight:
- 227.22
- MDL Number:
- MFCD02683609
- MOL File:
- 40093-94-5.mol
Boiling point | 497.6±55.0 °C(Predicted) |
---|---|
Density | 1.73±0.1 g/cm3(Predicted) |
storage temp. | Store at -20°C |
solubility | DMSO: 250 mg/mL (1100.26 mM) |
pka | 14.03±0.60(Predicted) |
Water Solubility | Water: 250 mg/mL (1100.26 mM) |
FDA UNII | 6BZN07BMW3 |
2'-DEOXY-L-CYTIDINE price More Price(13)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TRC | D288053 | 2''-Deoxy-L-cytidine | 40093-94-5 | 10mg | $45 | 2021-12-16 | Buy |
TRC | D288053 | 2''-Deoxy-L-cytidine | 40093-94-5 | 100mg | $265 | 2021-12-16 | Buy |
AK Scientific | 0870CB | Torcitabine | 40093-94-5 | 200mg | $306 | 2021-12-16 | Buy |
Biosynth Carbosynth | ND05747 | 2'-Deoxy-L-cytidine | 40093-94-5 | 500mg | $350 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | NUC0001453 | 2'-DEOXY-L-CYTIDINE 95.00% | 40093-94-5 | 5MG | $502.05 | 2021-12-16 | Buy |
2'-DEOXY-L-CYTIDINE Chemical Properties,Uses,Production
Description
Torcitabine (b-L-2u-deoxycytidine) (L-dC) is the b-L-enantiomer of the natural nucleoside D-cytidine. The drug is currently under development by Idenix as an antiviral agent for the treatment of chronic hepatitis B virus infection. Torcitabine has poor oral bioavailability, but its 3u,5u-divaline ester (val-L-dC) and the 3u-monovaline ester, valtorcitabine dihydrochloride, have excellent oral bioavailability and consequently the torcitabine prodrug, valtorcitabine, has replaced torcitabine in clinical development.
Uses
Torcitabine and its prodrug, valtorcitabine, are investigational drugs being developed solely for the treatment of chronic HBV infection. Torcitabine itself has undergone preliminary phase I/II clinical trials in HBeAg-positive patients, initially as the 3u,5u-divalyl prodrug in escalating doses of 50, 100, 200, and 400 mg/day, but later as the more stable monovaline ester form, valtorcitabine dihydrochloride, and administered to four cohorts in doses of 300, 600, 900, and 1200 mg/ day for 28 days.
2'-DEOXY-L-CYTIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
2'-DEOXY-L-CYTIDINE Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 6992 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21149 | 58 |
BOC Sciences | +16314854226 | inquiry@bocsci.com | United States | 19743 | 58 |
NewCan Biotech Limited | +86-0571-86912261 +8613735419629 | sales@newcanbio.com | China | 10027 | 58 |
changzhou huayang technology co., ltd | +8615250961469 | 2571773637@qq.com | China | 9821 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
PANNACEAN(HENAN)MEDICINE SCIENCE TECHNOLOGIES LTD | 0371-55159968 18137130222 | haifeng.zhang@pannacean.com | China | 387 | 58 |
Related articles
- Uses and toxicity of Torcitabine
- Torcitabine (b-L-2u-deoxycytidine) (L-dC) is the b-L-enantiomer of the natural nucleoside D-cytidine. The drug is currently un....
- Apr 8,2022
View Lastest Price from 2'-DEOXY-L-CYTIDINE manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2019-08-05 | 2'-DEOXY-L-CYTIDINE
40093-94-5
|
US $5.00 / KG | 1KG | 99% | 1ton | Career Henan Chemical Co |
- 2'-DEOXY-L-CYTIDINE
40093-94-5
- US $5.00 / KG
- 99%
- Career Henan Chemical Co