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Mosapride

Mosapride structure

CAS No.: 112885-41-3

Chemical Name:: Mosapride

Synonyms: Moza;Mosapid;TAK-370;Mosid-MT;MOSAPRIDE;Mosapride reference;Mosapride USP/EP/BP;((4-(4-fluorobenzyl)-2-morpholinyl)methyl)benzamide/mosapride;4-AMINO-5-CHLORO-2-ETHOXY-N-((4-(4-FLUOROBENZYL)-2-MORPHOLINYL)METHYL)BENZAMIDE;4-AMINO-5-CHLORO-2-ETHOXY-N-[4-(4-FLUORO-BENZYL)-MORPHOLIN-2-YLMETHYL]-BENZAMIDE

CBNumber:: CB3273304

Molecular Formula:: C21H25ClFN3O3

Molecular Weight:: 421.89

MDL Number:: MFCD00867430

MOL File:: 112885-41-3.mol

MSDS File:: SDS

Last updated:2023-09-20 16:43:00

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Mosapride Properties

Melting point	151-153°C
Boiling point	549.2±50.0 °C(Predicted)
Density	1.272±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	DMSO (Slightly), Methanol (Slightly)
form	Solid
pka	13.52±0.46(Predicted)
color	White to Off-White
CAS DataBase Reference	112885-41-3(CAS DataBase Reference)
FDA UNII	I8MFJ1C0BY
ATC code	A03FA09

Mosapride price More Price(24)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	M731000	Mosapride	112885-41-3	100mg	$215	2021-12-16	Buy
Usbiological	M4676-20	Mosapride	112885-41-3	10mg	$382	2021-12-16	Buy
Usbiological	282965	Mosapride	112885-41-3	50g	$921	2021-12-16	Buy
Matrix Scientific	074845	4-Amino-5-chloro-2-ethoxy-N-((4-(4-fluorobenzyl)-2-morpholinyl)methyl)benzamide 95+%	112885-41-3	5g	$998	2021-12-16	Buy
Matrix Scientific	074845	4-Amino-5-chloro-2-ethoxy-N-((4-(4-fluorobenzyl)-2-morpholinyl)methyl)benzamide 95+%	112885-41-3	1g	$370	2021-12-16	Buy

Product number	Packaging	Price	Buy
M731000	100mg	$215	Buy
M4676-20	10mg	$382	Buy
282965	50g	$921	Buy
074845	5g	$998	Buy
074845	1g	$370	Buy

Mosapride Chemical Properties,Uses,Production

Description

Mosapride citrate, a new gastroprokinetic benzamide was introduced in Japan as Gasmotin for the relief of gastrointestinal symptoms in patients with chronic gastritis, gastro-oesophageal reflux, dyspepsia and post-surgery use. Mosapride is synthesized by final amidation between the corresponding benzoic acid, itself obtained in 3 steps from methyl 4-acetamido salicylate, and the appropriate 2-aminomethyl-morpholine. Mosapride is a 5-HT4 partial agonist without notable activity for D2, 5-HT1 , 5-HT2, alpha-1 and alpha-2 receptors. In dogs, mosapride was as potent as cisapride to stimulate antral and duodenal motility. In most of species including man, mosapride undergoes extensive cleavage to a N-debenzylated metabolite which retains partial 5-HT4 activity but has potent 5-HT3 antagonist activity.

Chemical Properties

White to Off-White Crystalline Solid

Originator

Dainippon (Japan)

Uses

gastroprokinetic agent

Uses

A selective 5-HT4 receptor agonist. Gastroprokinetic.

Definition

ChEBI: Mosapride is a racemate comprising equimolar amounts of (R)- and (S)-mosapride. It is a gastroprokinetic agent which acts on 5-hydroxytryptamine type 4 (5-HT4) receptors in the gastrointestinal plexus, consequently increasing the release of acetylcholine and hence enhancing gastrointestinal motility and gastric emptying. It has a role as a gastrointestinal drug and a serotonergic agonist. It contains a (R)-mosapride and a (S)-mosapride.

brand name

Gasmotin

Hazard

A poison by ingestion.

Safety Profile

A poison by ingestion. When heated to decomposition it emits toxic vapors of NOx, F-, and Cl-.

Mosapride Preparation Products And Raw materials

Raw materials

Preparation Products

Mosapride citrate

Mosapride Suppliers

Global( 185)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63711	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49390	58
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6313	58
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	eric@witopchemical.com	China	23556	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-89586680 +86-18192503167	1026@dideu.com	China	9320	58
Chongqing Ensky Pharmaceutical Co.,Ltd.	+86-23-86815286 +86-13983794297	sales@ensky-chemical.com	China	87	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	29220	58

Supplier	Advantage
career henan chemical co	58
Chongqing Chemdad Co., Ltd	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
Career Henan Chemica Co	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	58
ANHUI WITOP BIOTECH CO., LTD	58
Shaanxi Dideu Medichem Co. Ltd	58
Chongqing Ensky Pharmaceutical Co.,Ltd.	58
Dideu Industries Group Limited	58

View Lastest Price from Mosapride manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2021-08-05	Mosapride USP/EP/BP 112885-41-3	US $1.10 / g	1g	0.999	100 Tons min	Dideu Industries Group Limited
2021-07-13	Mosapride 112885-41-3	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd
2021-07-09	Mosapride 112885-41-3	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd

Mosapride USP/EP/BP
112885-41-3
US $1.10 / g
0.999
Dideu Industries Group Limited

Mosapride
112885-41-3
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

Mosapride
112885-41-3
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

Mosapride Spectrum

Mosapride(112885-41-3)MS Mosapride(112885-41-3)¹HNMR

112885-41-3(Mosapride)Related Search:

4-AMINO-5-CHLORO-2-ETHOXY-N-[[4-(4-FLUOROBENZYL)-2-MORPHOLINYL]METHYL]BENZAMIDE CITRATE DIHYDRATE Mosapride Impurity 3 Mosapride Impurity 6 Mosapride Impurity 7 4-amino-5-chloro-2-ethoxy-N-((2-morpholinyl)methyl)benzamide

Mosapride Impurity 8 Mosapride Impurity 2 Mosapride Citric Amide Mosapride N-Oxide Des-4-fluorobenzyl Mosapride-d5

Mosapride Impurity 4 Mosapride Lactose Conjugate Mosapride Impurity 1 5-Amino-4-chloro-2-methylphenol 3-Hydroxyazetidine hydrochloride

2-(4-FLUOROBENZYLAMINO)ETHANOL 4-[(4-Fluorophenyl)methyl]-2-morpholinemethanamine (4-BENZYL-1,4-OXAZINAN-2-YL)METHYLAMINE

1of4

4-AMINO-5-CHLORO-2-ETHOXY-N-[[[4-(4-FLUOROPHENYL)METHYL]-2-MORPHOLINYL]METHYL]-BENZAMIDE ((4-(4-fluorobenzyl)-2-morpholinyl)methyl)benzamide/mosapride 4-Amino-5-Chloro-2-Ethoxy-N-((4-(4-Fluorobenzyl)-2-Morpholinyl)Methyl)Benzamide/Mosapride MOSAPRIDE Mosapride/4-Amino-5-Chloro-2-Ethoxy-N-((4-(4-Fluorobenzyl)-2-Morpholinyl)Methyl)Benzamide Mosapid Mosid-MT Moza BenzaMide,4-aMino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)Methyl]-2-Morpholinyl]Methyl]- 4-AMINO-5-CHLORO-2-ETHOXY-N-((4-(4-FLUOROBENZYL)-2-MORPHOLINYL)METHYL)BENZAMIDE 4-AMINO-5-CHLORO-2-ETHOXY-N-[4-(4-FLUORO-BENZYL)-MORPHOLIN-2-YLMETHYL]-BENZAMIDE Mosapride reference TAK-370 Mosapride USP/EP/BP Mosapride-FreebaseQ: What is Mosapride-Freebase Q: What is the CAS Number of Mosapride-Freebase Q: What is the storage condition of Mosapride-Freebase Q: What are the applications of Mosapride-Freebase 112885-41-3 12885-41-3 112885-41-5 C21H25ClFN3O3 API TAK-370, AS-4370, Gasmotin Pharmaceutical Intermediates Amines Aromatics Agonist Intermediates & Fine Chemicals Pharmaceuticals Agro Products