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Mosapride

Mosapride
Mosapride structure
CAS No.
112885-41-3
Chemical Name:
Mosapride
Synonyms
Moza;TAK-370;Mosapid;Mosid-MT;MOSAPRIDE;((4-(4-fluorobenzyl)-2-morpholinyl)methyl)benzamide/mosapride;4-AMINO-5-CHLORO-2-ETHOXY-N-((4-(4-FLUOROBENZYL)-2-MORPHOLINYL)METHYL)BENZAMIDE;4-AMINO-5-CHLORO-2-ETHOXY-N-[4-(4-FLUORO-BENZYL)-MORPHOLIN-2-YLMETHYL]-BENZAMIDE;4-AMINO-5-CHLORO-2-ETHOXY-N-[[[4-(4-FLUOROPHENYL)METHYL]-2-MORPHOLINYL]METHYL]-BENZAMIDE;BenzaMide,4-aMino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)Methyl]-2-Morpholinyl]Methyl]-
CBNumber:
CB3273304
Molecular Formula:
C21H25ClFN3O3
Formula Weight:
421.89
MOL File:
112885-41-3.mol

Mosapride Properties

Melting point:
151-153°C
Boiling point:
549.2±50.0 °C(Predicted)
Density 
1.272±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer
pka
13.52±0.46(Predicted)
CAS DataBase Reference
112885-41-3(CAS DataBase Reference)
FDA UNII
I8MFJ1C0BY

Mosapride Chemical Properties,Uses,Production

Description

Mosapride citrate, a new gastroprokinetic benzamide was introduced in Japan as Gasmotin for the relief of gastrointestinal symptoms in patients with chronic gastritis, gastro-oesophageal reflux, dyspepsia and post-surgery use. Mosapride is synthesized by final amidation between the corresponding benzoic acid, itself obtained in 3 steps from methyl 4-acetamido salicylate, and the appropriate 2-aminomethyl-morpholine. Mosapride is a 5-HT4 partial agonist without notable activity for D2, 5-HT1 , 5-HT2, alpha-1 and alpha-2 receptors. In dogs, mosapride was as potent as cisapride to stimulate antral and duodenal motility. In most of species including man, mosapride undergoes extensive cleavage to a N-debenzylated metabolite which retains partial 5-HT4 activity but has potent 5-HT3 antagonist activity.

Chemical Properties

White to Off-White Crystalline Solid

Originator

Dainippon (Japan)

Uses

A selective 5-HT4 receptor agonist. Gastroprokinetic.

Uses

gastroprokinetic agent

brand name

Gasmotin

Hazard

A poison by ingestion.

Safety Profile

A poison by ingestion. When heated to decomposition it emits toxic vapors of NOx, F-, and Cl-.

Mosapride Preparation Products And Raw materials

Raw materials

Preparation Products


Mosapride Suppliers

Global( 121)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 30045 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23977 58
Chongqing Chemdad Co., Ltd
+86-13650506873
sales@chemdad.com CHINA 35434 58
Alchem Pharmtech,Inc.
8485655694
sales@alchempharmtech.com United States 63728 58
HENAN BON INDUSTRIAL CO.,LTD
0371-55170695
info@hnbon.com CHINA 20535 58
CONIER CHEM AND PHARMA LIMITED
86-18523575427
sales@conier.com CHINA 47486 58
Zhuozhou Wenxi import and Export Co., Ltd
+8613111626072
+8613111626072 zzwenxi@126.com CHINA 7497 58
Amadis Chemical Company Limited
0086-571-89925085
0086-571-89925065 sales@amadischem.com China 132149 58
Shenzhen Sendi Biotechnology Co.Ltd. 0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3194 55
Mainchem Co., Ltd. +86-0592-6210733
+86-0592-6210733 sale@mainchem.com CHINA 32444 55

View Lastest Price from Mosapride manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2020-05-06 Mosapride
112885-41-3
US $1.00-1.00 / KG 1g 99% 50tons Shaanxi Dideu Medichem Co. Ltd
2018-08-20 4-Amino-5-chloro-2-ethoxy-N-((4-(4-fluorobenzyl)-2-morpholinyl)methyl)benzamide
112885-41-3
US $1.00 / KG 1G 98% 100KG career henan chemical co

112885-41-3(Mosapride)Related Search:


  • TAK-370
  • Mosapride/4-Amino-5-Chloro-2-Ethoxy-N-((4-(4-Fluorobenzyl)-2-Morpholinyl)Methyl)Benzamide
  • Mosapid
  • Mosid-MT
  • Moza
  • BenzaMide,4-aMino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)Methyl]-2-Morpholinyl]Methyl]-
  • MOSAPRIDE
  • 4-AMINO-5-CHLORO-2-ETHOXY-N-((4-(4-FLUOROBENZYL)-2-MORPHOLINYL)METHYL)BENZAMIDE
  • 4-AMINO-5-CHLORO-2-ETHOXY-N-[4-(4-FLUORO-BENZYL)-MORPHOLIN-2-YLMETHYL]-BENZAMIDE
  • 4-AMINO-5-CHLORO-2-ETHOXY-N-[[[4-(4-FLUOROPHENYL)METHYL]-2-MORPHOLINYL]METHYL]-BENZAMIDE
  • ((4-(4-fluorobenzyl)-2-morpholinyl)methyl)benzamide/mosapride
  • 4-Amino-5-Chloro-2-Ethoxy-N-((4-(4-Fluorobenzyl)-2-Morpholinyl)Methyl)Benzamide/Mosapride
  • 112885-41-3
  • 12885-41-3
  • 112885-41-5
  • C21H25ClFN3O3
  • Agonist
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Pharmaceutical Intermediates
  • Amines
  • Aromatics
  • API
  • TAK-370, AS-4370, Gasmotin
  • Agro Products
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