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Methylprednisolone

Methylprednisolone
Methylprednisolone structure
CAS No.
83-43-2
Chemical Name:
Methylprednisolone
Synonyms
MEPRDL;U 7532;MEDROL;Medrat;Medrate;Moderin;Besonia;Urbason;Wyacort;MEDRONE
CBNumber:
CB3274376
Molecular Formula:
C22H30O5
Formula Weight:
374.47
MOL File:
83-43-2.mol

Methylprednisolone Properties

Melting point:
228-237°C (dec.)
alpha 
D20 +83° (dioxane)
Boiling point:
423.47°C (rough estimate)
Density 
1.0868 (rough estimate)
refractive index 
82 ° (C=1, Dioxane)
storage temp. 
0-6°C
solubility 
chloroform/methanol (9:1): 50 mg/mL, clear, faintly yellow
form 
neat
Merck 
14,6111
BRN 
2340300
CAS DataBase Reference
83-43-2(CAS DataBase Reference)
NIST Chemistry Reference
1,4-Pregnadiene-3,20-dione, 11beta,17alpha,21-trihydroxy-6alpha-methyl-(83-43-2)
EPA Substance Registry System
Pregna-1,4-diene- 3,20-dione, 11,17,21-trihydroxy-6-methyl-, (6.alpha.,11.beta.)-(83-43-2)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS08
Signal word  Danger
Hazard statements  H360D-H373
Precautionary statements  P201-P202-P260-P280-P308+P313-P501
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  22-36-26
WGK Germany  2
RTECS  TU4146000
8-10-23
HS Code  2937290000

Methylprednisolone price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 46436 6α-Methylprednisolone VETRANAL 83-43-2 100mg $184 2018-11-20 Buy
Sigma-Aldrich M0639 6α-Methylprednisolone ≥98% 83-43-2 1g $910 2018-11-20 Buy
Cayman Chemical 15013 Methylprednisolone ≥98% 83-43-2 5g $225 2018-11-13 Buy
Cayman Chemical 15013 Methylprednisolone ≥98% 83-43-2 1g $72 2018-11-13 Buy
Sigma-Aldrich PHR1717 Methylprednisolone Pharmaceutical Secondary Standard; Certified Reference Material 83-43-2 500mg $73.1 2018-11-20 Buy

Methylprednisolone Chemical Properties,Uses,Production

Chemical Properties

White to Off-White Crystalline Powder

Uses

A glucocorticoid

Definition

ChEBI: The 6alpha-stereoisomer of 6-methylprednisolone.

brand name

Medrol (Pharmacia & Upjohn).

General Description

Methylprednisolone, 11β,17,21-trihydroxy-6α-methyl-1,4-pregnadiene-3,20-dione, isavailable unmodified or as ester derivatives.
Methylprednisolone acetate, USP
Methylprednisolone sodium succinate, USP.

Safety Profile

Moderately toxic by intraperitoneal route. A steroid hormone. Human systemic effects include arrhythmias, blood pressure lowering, heart rate changes, increased body temperature, pulse rate increase, respiratory depression. When heated to decomposition it emits acrid smoke and irritating fumes.

Veterinary Drugs and Treatments

Purification Methods

Recrystallise medrol from EtOAc. The UV has max at in 95% EtOH 243nm ( 14,875). The 21-acetoxy derivative has m 205-208o (from EtOAc), and [] D +95o ( c 1, CHCl3). [Spero et al. J Am Chem Soc 78 6213 1956; Fried et al. J Am Chem Soc 81 1235 1959; 1H NMR: Slomp & McGarvey J Am Chem Soc 81 2200 1959, Beilstein 8 IV 3498.]

Methylprednisolone Preparation Products And Raw materials

Raw materials

Preparation Products


Methylprednisolone Suppliers

Global( 210)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3194 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21676 58
Beijing Cooperate Pharmaceutical Co.,Ltd.
+86-10-60279497 +86(0)15646567669
+86-10-60279497 sales01@cooperate-pharm.com CHINA 1817 55
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20672 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32447 55
Hubei XinRunde Chemical Co., Ltd.
+8615102730682; +8618874586545
02783214688 bruce@xrdchem.cn CHINA 535 55
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 30001 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23980 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 sales@jushengtech.com CHINA 28236 58
QUALITY CONTROL CHEMICALS INC.
(323) 306-3136
(626) 453-0409 orders@qcchemical.com United States 8407 58

View Lastest Price from Methylprednisolone manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2019-07-17 Methylprednisolone
83-43-2
US $1.00 / g 1g 99% 500kg Cangzhou Wanyou New Material Technology Co.,Ltd
2018-08-20 Methylprednisolone
83-43-2
US $1.00 / KG 1G 98% 100KG career henan chemical co
2018-03-13 Methylprednisolon
83-43-2
US $10.00 / KG 10G 99% 10MT Hubei XinRunde Chemical Co., Ltd.

Methylprednisolone Spectrum


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