Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>(2S)-1-[[(2S)-1-(1-Oxo-4-phenylbutyl)-2-pyrrolidinyl]carbonyl]-2-pyrrolidinecarbonitrile

(2S)-1-[[(2S)-1-(1-Oxo-4-phenylbutyl)-2-pyrrolidinyl]carbonyl]-2-pyrrolidinecarbonitrile

(2S)-1-[[(2S)-1-(1-Oxo-4-phenylbutyl)-2-pyrrolidinyl]carbonyl]-2-pyrrolidinecarbonitrile Structure
(2S)-1-[[(2S)-1-(1-Oxo-4-phenylbutyl)-2-pyrrolidinyl]carbonyl]-2-pyrrolidinecarbonitrile structure
CAS No.
796874-99-2
Chemical Name:
(2S)-1-[[(2S)-1-(1-Oxo-4-phenylbutyl)-2-pyrrolidinyl]carbonyl]-2-pyrrolidinecarbonitrile
Synonyms
KYP-2047;KYP-2047 >=95% (HPLC);KYP-2047;KYP 2047;KYP2047;(2S)-1-[[(2S)-1-(1-Oxo-4-phenylbutyl)-2-pyrrolidinyl]carbonyl]-2-pyrrolidinecarbonitrile;2-Pyrrolidinecarbonitrile, 1-[[(2S)-1-(1-oxo-4-phenylbutyl)-2-pyrrolidinyl]carbonyl]-, (2S)-;eNOS,inhibit,POP,Neurotensin,Angiopoietins,MDM-2/p53,KYP 2047,prolyl oligopeptidase,Glioblastoma,VEGF,Prolyl Endopeptidase (PREP),Inhibitor,U-87 cell,Apoptosis,KYP-2047,KYP2047
CBNumber:
CB32750483
Molecular Formula:
C20H25N3O2
Molecular Weight:
339.43
MDL Number:
MFCD22201003
MOL File:
796874-99-2.mol
MSDS File:
SDS
Last updated:2023-06-30 15:45:59
Request For Quotation

(2S)-1-[[(2S)-1-(1-Oxo-4-phenylbutyl)-2-pyrrolidinyl]carbonyl]-2-pyrrolidinecarbonitrile Properties

Boiling point 605.5±55.0 °C(Predicted)
Density 1.19±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility Soluble in DMSO
pka -1.98±0.40(Predicted)
form oil
color white to light brown
FDA UNII 8J78D7C2FJ

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H319
Precautionary statements  P305+P351+P338
Hazard Codes  Xi
Risk Statements  36
Safety Statements  26
WGK Germany  3

(2S)-1-[[(2S)-1-(1-Oxo-4-phenylbutyl)-2-pyrrolidinyl]carbonyl]-2-pyrrolidinecarbonitrile price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML0208 KYP-2047 ≥95% (HPLC) 796874-99-2 5mg $179 2024-03-01 Buy
Sigma-Aldrich SML0208 KYP-2047 ≥95% (HPLC) 796874-99-2 25mg $720 2024-03-01 Buy
Tocris 6272 KYP2047 ≥98%(HPLC) 796874-99-2 25 $509 2021-12-16 Buy
DC Chemicals DC10669 KYP-2047 >98% 796874-99-2 100mg $750 2021-12-16 Buy
DC Chemicals DC10669 KYP-2047 >98% 796874-99-2 1g $2700 2021-12-16 Buy
Product number Packaging Price Buy
SML0208 5mg $179 Buy
SML0208 25mg $720 Buy
6272 25 $509 Buy
DC10669 100mg $750 Buy
DC10669 1g $2700 Buy

(2S)-1-[[(2S)-1-(1-Oxo-4-phenylbutyl)-2-pyrrolidinyl]carbonyl]-2-pyrrolidinecarbonitrile Chemical Properties,Uses,Production

Uses

KYP-2047 may be used in prolyl endopeptidase-mediated cell signaling studies.

Biochem/physiol Actions

KYP-2047 is a very potent, selective inhibitor of Prolyl oligopeptidase (POP), also known as prolyl endopeptidase (PEP or PE). Ki = .023nM (porcine). KYP-2047 has been found to be neuroprotective against glutamate and oxygen, glucose deprivation in vitro. It has also been used to inhibit the formation of AcSDKP from its precursor 43-mer thymosin β4 (Tβ4). Ac-SDKP is involved in hemopoietic stem cell differentiation, is pro-angiogenic and antifibrogenic.

storage

Store at -20°C

(2S)-1-[[(2S)-1-(1-Oxo-4-phenylbutyl)-2-pyrrolidinyl]carbonyl]-2-pyrrolidinecarbonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

(2S)-1-[[(2S)-1-(1-Oxo-4-phenylbutyl)-2-pyrrolidinyl]carbonyl]-2-pyrrolidinecarbonitrile Suppliers

Global( 16)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 support@targetmol.com United States 19973 58
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 52927 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 18892239720 psaitong@jm-bio.com China 12308 58
Shanghai ChuangYan Chemical Technology Co., Ltd. 021-11111111 11111111111 546919421@qq.com China 2990 55
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
DC Chemicals 021-58447131 13564518121 sales@dcchemicals.com China 9414 58
Changzhou Chenhong Biotechnology Co., Ltd. 0519-85788828 13775037613 sales@chemrenpharm.com China 3538 58
Cangzhou Pintuo Biotechnology Co., Ltd. 15231732623 1979763395@qq.com China 187 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44941 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Aladdin Scientific 		58
Beijing Jin Ming Biotechnology Co., Ltd. 58
Shanghai ChuangYan Chemical Technology Co., Ltd. 55
Sigma-Aldrich 80
Shanghai Hongye Biotechnology Co. Ltd 58
DC Chemicals 58
Changzhou Chenhong Biotechnology Co., Ltd. 58
Cangzhou Pintuo Biotechnology Co., Ltd. 58
Energy Chemical 58
(2S)-1-[[(2S)-1-(1-Oxo-4-phenylbutyl)-2-pyrrolidinyl]carbonyl]-2-pyrrolidinecarbonitrile KYP-2047 KYP-2047;KYP 2047;KYP2047 KYP-2047 >=95% (HPLC) eNOS,inhibit,POP,Neurotensin,Angiopoietins,MDM-2/p53,KYP 2047,prolyl oligopeptidase,Glioblastoma,VEGF,Prolyl Endopeptidase (PREP),Inhibitor,U-87 cell,Apoptosis,KYP-2047,KYP2047 2-Pyrrolidinecarbonitrile, 1-[[(2S)-1-(1-oxo-4-phenylbutyl)-2-pyrrolidinyl]carbonyl]-, (2S)- 796874-99-2