TN ANTIGEN
- CAS No.
- 67262-86-6
- Chemical Name:
- TN ANTIGEN
- Synonyms
- TN ANTIGEN;TN EPITOPE;GALNAC-ALPHA1-O-SER;GalNac-α-1-O-serine;Ser(α-D-GalNHAc)-OH;Olanzapine Impurity 50;Galactose Impurity 9 (Tn Epitope);N-ACETYLGALACTOSAMINE, ALPHA1-O-SERINE;N-Acetyl-α-D-galactosaMinyl- 1-O-serine;N-ACETYL-ALPHA-D-GALACTOSAMINYL-1-O-SERINE
- CBNumber:
- CB3283024
- Molecular Formula:
- C11H20N2O8
- Molecular Weight:
- 308.29
- MDL Number:
- MFCD01863462
- MOL File:
- Mol file
- MSDS File:
- SDS
TN ANTIGEN price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 53886 | Tn Antigen ≥99.0% (TLC) | 67262-86-6 | 1mg | $404 | 2024-03-01 | Buy |
| Usbiological | T2660-30 | Tn Epitope | 67262-86-6 | 1mg | $375 | 2021-12-16 | Buy |
| TRC | T020050 | TnEpitope | 67262-86-6 | 5mg | $450 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | ATG0000871 | Tn Antigen 95.00% | 67262-86-6 | 1MG | $673.08 | 2021-12-16 | Buy |
| Biosynth Carbosynth | MA07378 | 2-Acetamido-2-deoxy-a-D-galactopyranosyl serine | 67262-86-6 | 5mg | $425 | 2021-12-16 | Buy |
TN ANTIGEN Chemical Properties,Uses,Production
Chemical Properties
TN ANTIGEN is Yellow Solid
Uses
TN ANTIGEN is a cancer associated carbohydrate tumor antigen which may be effective as cancer specific targets for immunotherapy as well as in the development of diagnostic monoclonal antibodies. Has been used or considered for use in human vaccines
Uses
A cancer associated carbohydrate tumor antigen which may be effective as cancer specific targets for immunotherapy as well as in the development of diagnostic monoclonal antibodies. Has been used or considered for use in human vaccines.
Definition
ChEBI: O-(N-acetyl-alpha-D-galactosaminyl)-L-serine is a non-proteinogenic L-amino acid that is N-acetyl-alpha-D-galactosamine linked via an alpha glycosidic bond to the O at position 3 of L-serine. It has a role as a tumour antigen. It is a L-serine derivative and a non-proteinogenic L-alpha-amino acid.
General Description
Tn antigen?is a truncated O-glycan, that is commonly noticed in colorectal cancer (CRC). It is usually expressed at high levels in cancer cells. Tn antigen is small in size and simple in structure. It has a non-physiological glycan structure in humans, hence it may be identified as foreign by the immune system.
Biochem/physiol Actions
Tn antigen stimulates colorectal cancer metastasis through the activation of epithelial-mesenchymal transition, mediated by H-Ras. It acts as a precursor to several significant complex O-glycans. Subpopulations of blood cells in all lineages carrying the Tn antigen results in a hematological disorder called Tn syndrome.
TN ANTIGEN Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| China National Standard Pharmaceutical Corporation Limited | +8615391658522 | overseasales@yongstandards.com | China | 11927 | 58 |
| Young Lively PharminBlock Co.,Ltd | +undefined18600731423 | jason_gao@yl-pharminblock.com | China | 1944 | 58 |
| Shenzhen Excellent Biomedical Technology Co., Ltd. | 18318671572 | 2850803126@qq.com | China | 4993 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 94838 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| Guangzhou Isun Pharmaceutical Co., Ltd | 020-39119399 18927568969 | isunpharm@qq.com | China | 4428 | 55 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |